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Altered global and regional left ventricular function in horses with aortic valve insufficiency measured by tissue Doppler imaging and 2D speckle tracking

Annelies Decloedt UGent, Tinne Verheyen UGent, Dominique De Clercq UGent and Gunther van Loon UGent (2012) Proceedings of the 2nd scientific meeting of the Faculty of Veterinary Medicine (University of Liège, Belgium). p.24-24
abstract
Aims: Significant aortic regurgitation (AR) may cause left ventricular (LV) dilatation and heart failure. The aim was to quantify LV function in AR horses by tissue Doppler imaging (TDI) and two-dimensional speckle tracking (2DST). Methods: Echocardiographic examinations were performed on ten healthy horses (10±4 years;509±58 kg) and fourteen horses with significant AR (17±4 years;497±93 kg). By 2DST, global radial (SR) and longitudinal (SL) strain were measured. Regional systolic radial displacement (DRS) by 2DST and velocity (VS) by TDI were measured in the interventricular septum and LV free wall. LV end-diastolic internal diameter (LVIDd) and fractional shortening (FS) were measured from a short-axis M-mode at chordal level. Results: Seven horses showed moderate AR (LVIDd range 11.0-12.7 cm), seven severe AR (LVIDd 13.3-16.9 cm). FS, SR and SL showed no significant differences. However, SL was significantly correlated with LVIDd in healthy horses and moderate AR (r=-0.72; P<0.01) but inversely correlated in severe AR (r=0.82, p<0.05), suggesting LV contractile dysfunction. Septal DRS was correlated with LVIDd (r=0.667; P<0.001). Compared to healthy horses (17.4±3.1 mm), DRS was increased in horses with moderate (21.1±4.2 mm) and severe (27.1±3.8 mm) AR (P<0.05). Similarly, septal VS was correlated with LVIDd (-0.778; P<0.001) and increased in horses with moderate (-8.3±1.2 cm/s) and severe (-10.8±1.9 cm/s) AR compared to healthy horses (4.4±1.2 cm/s). This indicates increased septal motion in AR horses both with and without LV dilatation. Conclusion: TDI and 2DST allow quantification of altered LV function due to AR. The prognostic value of these measurements requires further investigation.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
keyword
echocardiography, myocardial function, valvular regurgitation
in
Proceedings of the 2nd scientific meeting of the Faculty of Veterinary Medicine (University of Liège, Belgium)
pages
24 - 24
publisher
Université de Liège. Faculté de Médecine vétérinaire
place of publication
Liège, Belgium
conference name
2nd Scientific meeting of the Faculty of Veterinary Medicine
conference location
Liège, Belgium
conference start
2012-10-19
conference end
2012-10-19
ISBN
9782875430274
language
English
UGent publication?
yes
classification
C3
id
3036208
handle
http://hdl.handle.net/1854/LU-3036208
date created
2012-10-29 14:09:54
date last changed
2012-10-30 09:22:10
@inproceedings{3036208,
  abstract     = {Aims: Significant aortic regurgitation (AR) may cause left ventricular (LV) dilatation and heart failure. The aim was to quantify LV function in AR horses by tissue Doppler imaging (TDI) and two-dimensional speckle tracking (2DST).
Methods: Echocardiographic examinations were performed on ten healthy horses (10{\textpm}4 years;509{\textpm}58 kg) and fourteen horses with significant AR (17{\textpm}4 years;497{\textpm}93 kg). By 2DST, global radial (SR) and longitudinal (SL) strain were measured. Regional systolic radial displacement (DRS) by 2DST and velocity (VS) by TDI were measured in the interventricular septum and LV free wall. LV end-diastolic internal diameter (LVIDd) and fractional shortening (FS) were measured from a short-axis M-mode at chordal level.
Results: Seven horses showed moderate AR (LVIDd range 11.0-12.7 cm), seven severe AR (LVIDd 13.3-16.9 cm). FS, SR and SL showed no significant differences. However, SL was significantly correlated with LVIDd in healthy horses and moderate AR (r=-0.72; P{\textlangle}0.01) but inversely correlated in severe AR (r=0.82, p{\textlangle}0.05), suggesting LV contractile dysfunction. Septal DRS was correlated with LVIDd (r=0.667; P{\textlangle}0.001). Compared to healthy horses (17.4{\textpm}3.1 mm), DRS was increased in horses with moderate (21.1{\textpm}4.2 mm) and severe (27.1{\textpm}3.8 mm) AR (P{\textlangle}0.05). Similarly, septal VS was correlated with LVIDd (-0.778; P{\textlangle}0.001) and increased in horses with moderate (-8.3{\textpm}1.2 cm/s) and severe (-10.8{\textpm}1.9 cm/s) AR compared to healthy horses (4.4{\textpm}1.2 cm/s). This indicates increased septal motion in AR horses both with and without LV dilatation.
Conclusion: TDI and 2DST allow quantification of altered LV function due to AR. The prognostic value of these measurements requires further investigation.},
  author       = {Decloedt, Annelies and Verheyen, Tinne and De Clercq, Dominique and van Loon, Gunther},
  booktitle    = {Proceedings of the 2nd scientific meeting of the Faculty of Veterinary Medicine (University of Li{\`e}ge, Belgium)},
  isbn         = {9782875430274},
  keyword      = {echocardiography,myocardial function,valvular regurgitation},
  language     = {eng},
  location     = {Li{\`e}ge, Belgium},
  pages        = {24--24},
  publisher    = {Universit{\'e} de Li{\`e}ge. Facult{\'e} de M{\'e}decine v{\'e}t{\'e}rinaire},
  title        = {Altered global and regional left ventricular function in horses with aortic valve insufficiency measured by tissue Doppler imaging and 2D speckle tracking},
  year         = {2012},
}

Chicago
Decloedt, Annelies, Tinne Verheyen, Dominique De Clercq, and Gunther van Loon. 2012. “Altered Global and Regional Left Ventricular Function in Horses with Aortic Valve Insufficiency Measured by Tissue Doppler Imaging and 2D Speckle Tracking.” In Proceedings of the 2nd Scientific Meeting of the Faculty of Veterinary Medicine (University of Liège, Belgium), 24–24. Liège, Belgium: Université de Liège. Faculté de Médecine vétérinaire.
APA
Decloedt, A., Verheyen, T., De Clercq, D., & van Loon, G. (2012). Altered global and regional left ventricular function in horses with aortic valve insufficiency measured by tissue Doppler imaging and 2D speckle tracking. Proceedings of the 2nd scientific meeting of the Faculty of Veterinary Medicine (University of Liège, Belgium) (pp. 24–24). Presented at the 2nd Scientific meeting of the Faculty of Veterinary Medicine, Liège, Belgium: Université de Liège. Faculté de Médecine vétérinaire.
Vancouver
1.
Decloedt A, Verheyen T, De Clercq D, van Loon G. Altered global and regional left ventricular function in horses with aortic valve insufficiency measured by tissue Doppler imaging and 2D speckle tracking. Proceedings of the 2nd scientific meeting of the Faculty of Veterinary Medicine (University of Liège, Belgium). Liège, Belgium: Université de Liège. Faculté de Médecine vétérinaire; 2012. p. 24–24.
MLA
Decloedt, Annelies, Tinne Verheyen, Dominique De Clercq, et al. “Altered Global and Regional Left Ventricular Function in Horses with Aortic Valve Insufficiency Measured by Tissue Doppler Imaging and 2D Speckle Tracking.” Proceedings of the 2nd Scientific Meeting of the Faculty of Veterinary Medicine (University of Liège, Belgium). Liège, Belgium: Université de Liège. Faculté de Médecine vétérinaire, 2012. 24–24. Print.