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Adjuvantia of de queeste naar het ultieme vaccin

Anton De Spiegeleer UGent, Matthias Vandekerckhove UGent, SANDRINE ASPESLAGH UGent and Dirk Elewaut UGent (2012) TIJDSCHRIFT VOOR GENEESKUNDE. 68(19). p.925-933
abstract
Vaccinations are one of the most important discoveries in medical science. The administration of pathogenic antigens stimulates the immune system to raise antigen-specific responses. Subsequently, a later infection will rapidly be recognized and defeated. Unfortunately, for many infectious diseases nowadays vaccine-induced protection is not strong enough, a problem especially true for the elderly because of their diminished cellular immunity. Because of the ageing of the global population, an important issue arises. In the quest for more effective and safe vaccines, the adjuvants play an increasingly important role. They help setting up an adaptive immune response against the antigen. In this article, the mode of action, the clinical importance of the current adjuvants and the promising group of invariant natural killer T cell activators are reviewed, the authors intending to contribute to a rational use of adjuvants in vaccines.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
journal title
TIJDSCHRIFT VOOR GENEESKUNDE
Tijdschr. Geneeskd.
volume
68
issue
19
pages
925 - 933
ISSN
0371-683X
DOI
10.2143/TVG.68.19.2001262
language
Dutch
UGent publication?
yes
classification
A2
copyright statement
I have transferred the copyright for this publication to the publisher
id
3020926
handle
http://hdl.handle.net/1854/LU-3020926
date created
2012-10-10 21:32:30
date last changed
2012-10-16 11:20:25
@article{3020926,
  abstract     = {Vaccinations are one of the most important discoveries in medical science. The administration of pathogenic antigens stimulates the immune system to raise antigen-specific responses. Subsequently, a later infection will rapidly be recognized and defeated. Unfortunately, for many infectious diseases nowadays vaccine-induced protection is not strong enough, a problem especially true for the elderly because of their diminished cellular immunity. Because of the ageing of the global population, an important issue arises. In the quest for more effective and safe vaccines, the adjuvants play an increasingly important role. They help setting up an adaptive immune response against the antigen. In this article, the mode of action, the clinical importance of the current adjuvants and the promising group of invariant natural killer T cell activators are reviewed, the authors intending to contribute to a rational use of adjuvants in vaccines.},
  author       = {De Spiegeleer, Anton and Vandekerckhove, Matthias and ASPESLAGH, SANDRINE and Elewaut, Dirk},
  issn         = {0371-683X},
  journal      = {TIJDSCHRIFT VOOR GENEESKUNDE},
  language     = {dut},
  number       = {19},
  pages        = {925--933},
  title        = {Adjuvantia of de queeste naar het ultieme vaccin},
  url          = {http://dx.doi.org/10.2143/TVG.68.19.2001262},
  volume       = {68},
  year         = {2012},
}

Chicago
De Spiegeleer, Anton, Matthias Vandekerckhove, Sandrine Aspeslagh, and Dirk Elewaut. 2012. “Adjuvantia of De Queeste Naar Het Ultieme Vaccin.” Tijdschrift Voor Geneeskunde 68 (19): 925–933.
APA
De Spiegeleer, A., Vandekerckhove, M., Aspeslagh, S., & Elewaut, D. (2012). Adjuvantia of de queeste naar het ultieme vaccin. TIJDSCHRIFT VOOR GENEESKUNDE, 68(19), 925–933.
Vancouver
1.
De Spiegeleer A, Vandekerckhove M, Aspeslagh S, Elewaut D. Adjuvantia of de queeste naar het ultieme vaccin. TIJDSCHRIFT VOOR GENEESKUNDE. 2012;68(19):925–33.
MLA
De Spiegeleer, Anton, Matthias Vandekerckhove, Sandrine Aspeslagh, et al. “Adjuvantia of De Queeste Naar Het Ultieme Vaccin.” TIJDSCHRIFT VOOR GENEESKUNDE 68.19 (2012): 925–933. Print.