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Creatine kinase isoenzyme BB concentrations in the cerebrospinal fluid of newborns : relationship to short-term outcome

(1991) PEDIATRICS. 88(6). p.1204-1210
Author
Organization
Abstract
Creatine kinase brain isoenzyme (CK-BB) was determined in cerebrospinal fluid of 150 neonates by a newly developed immunoenzymatic assay. Newborns with a documented neurologic disorder (intraventricular hemorrhage, postasphyxial encephalopathy, central nervous system infection, or persistent periventricular intraparenchymal echodensities) showed markedly higher concentrations of immunoreactive CK-BB than did the normal newborns or those with subarachnoid hemorrhage. In neonates with seizures the data suggest that the underlying neurologic disorder accounts for the higher CK-BB values and not the seizures per se. High concentrations of CK-BB in the neonatal period were followed by poor short-term outcome.
Keywords
CEREBROSPINAL FLUID, CREATINE KINASE ISOENZYME-BB, NEONATE, NEUROLOGIC DISORDER, SHORT-TERM OUTCOME, BIRTH-WEIGHT INFANTS, SEVERE HEAD-INJURY, BRAIN-DAMAGE, INTRAVENTRICULAR HEMORRHAGE, PRETERM INFANTS, BLOOD-CELLS, CORD-BLOOD, CK-BB, SERUM, PHOSPHOKINASE

Citation

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Chicago
Depraeter, C, Piet Vanhaesebrouck, P Govaert, Joris Delanghe, and Juliaan Leroy. 1991. “Creatine Kinase Isoenzyme BB Concentrations in the Cerebrospinal Fluid of Newborns : Relationship to Short-term Outcome.” Pediatrics 88 (6): 1204–1210.
APA
Depraeter, C., Vanhaesebrouck, P., Govaert, P., Delanghe, J., & Leroy, J. (1991). Creatine kinase isoenzyme BB concentrations in the cerebrospinal fluid of newborns : relationship to short-term outcome. PEDIATRICS, 88(6), 1204–1210.
Vancouver
1.
Depraeter C, Vanhaesebrouck P, Govaert P, Delanghe J, Leroy J. Creatine kinase isoenzyme BB concentrations in the cerebrospinal fluid of newborns : relationship to short-term outcome. PEDIATRICS. 1991;88(6):1204–10.
MLA
Depraeter, C, Piet Vanhaesebrouck, P Govaert, et al. “Creatine Kinase Isoenzyme BB Concentrations in the Cerebrospinal Fluid of Newborns : Relationship to Short-term Outcome.” PEDIATRICS 88.6 (1991): 1204–1210. Print.
@article{301754,
  abstract     = {Creatine kinase brain isoenzyme (CK-BB) was determined in cerebrospinal fluid of 150 neonates by a newly developed immunoenzymatic assay. Newborns with a documented neurologic disorder (intraventricular hemorrhage, postasphyxial encephalopathy, central nervous system infection, or persistent periventricular intraparenchymal echodensities) showed markedly higher concentrations of immunoreactive CK-BB than did the normal newborns or those with subarachnoid hemorrhage. In neonates with seizures the data suggest that the underlying neurologic disorder accounts for the higher CK-BB values and not the seizures per se. High concentrations of CK-BB in the neonatal period were followed by poor short-term outcome.},
  author       = {Depraeter, C and Vanhaesebrouck, Piet and Govaert, P and Delanghe, Joris and Leroy, Juliaan},
  issn         = {0031-4005},
  journal      = {PEDIATRICS},
  language     = {eng},
  number       = {6},
  pages        = {1204--1210},
  title        = {Creatine kinase isoenzyme BB concentrations in the cerebrospinal fluid of newborns : relationship to short-term outcome},
  volume       = {88},
  year         = {1991},
}