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Nanotechnology and pharmaceutical inhalation aerosols

Ashok Patel UGent and Pradeep R Vavia (2007) INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY. 45(2). p.166-174
abstract
Pharmaceutical inhalation aerosols have been playing a crucial role in the health and well being of millions of people throughout the world for many years. The technology's continual advancement, the ease of use and the more desirable pulmonary-rather-than-needle delivery for systemic drugs has increased the attraction for the pharmaceutical aerosol in recent years. But administration of drugs by the pulmonary route is technically challenging because oral deposition can be high, and variations in inhalation technique can affect the quantity of drug delivered to the lungs. Recent advances in nanotechnology, particularly drug delivery field have encouraged formulation scientists to expand their reach in solving tricky problems related to drug delivery. Moreover, application of nanotechnology to aerosol science has opened up a new category of pharmaceutical aerosols (collectively known as nanoenabled-aerosols) with added advantages and effectiveness. In this review, some of the latest approaches of nano-enabled aerosol drug delivery system (including nano-suspension, trojan particles, bioadhesive nanoparticles and smart particle aerosols) that can be employed successfully to overcome problems of conventional aerosol systems have been introduced.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
INTERLEUKIN-2 LIPOSOMES, INHALED PARTICLES, HUMAN RESPIRATORY-TRACT, PULMONARY DRUG-DELIVERY, trojan particles, smart particle aerosols, nanosuspension, bioadhesive nanoparticles, inhalation aerosols, LATEX-PARTICLES, ADULT-RATS, NANOPARTICLES, SIZE, PHAGOCYTOSIS, DEPOSITION
journal title
INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY
Indian J. Exp. Biol.
volume
45
issue
2
pages
166 - 174
Web of Science type
Review
Web of Science id
000244594800004
JCR category
BIOLOGY
JCR impact factor
0.551 (2007)
JCR rank
52/70 (2007)
JCR quartile
3 (2007)
ISSN
0019-5189
language
English
UGent publication?
no
classification
A1
copyright statement
I have retained and own the full copyright for this publication
id
3007977
handle
http://hdl.handle.net/1854/LU-3007977
alternative location
http://nopr.niscair.res.in/handle/123456789/5741
date created
2012-10-05 23:08:21
date last changed
2012-10-09 16:20:44
@article{3007977,
  abstract     = {Pharmaceutical inhalation aerosols have been playing a crucial role in the health and well being of millions of people throughout the world for many years. The technology's continual advancement, the ease of use and the more desirable pulmonary-rather-than-needle delivery for systemic drugs has increased the attraction for the pharmaceutical aerosol in recent years. But administration of drugs by the pulmonary route is technically challenging because oral deposition can be high, and variations in inhalation technique can affect the quantity of drug delivered to the lungs. Recent advances in nanotechnology, particularly drug delivery field have encouraged formulation scientists to expand their reach in solving tricky problems related to drug delivery. Moreover, application of nanotechnology to aerosol science has opened up a new category of pharmaceutical aerosols (collectively known as nanoenabled-aerosols) with added advantages and effectiveness. In this review, some of the latest approaches of nano-enabled aerosol drug delivery system (including nano-suspension, trojan particles, bioadhesive nanoparticles and smart particle aerosols) that can be employed successfully to overcome problems of conventional aerosol systems have been introduced.},
  author       = {Patel, Ashok and Vavia, Pradeep R},
  issn         = {0019-5189},
  journal      = {INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY},
  keyword      = {INTERLEUKIN-2 LIPOSOMES,INHALED PARTICLES,HUMAN RESPIRATORY-TRACT,PULMONARY DRUG-DELIVERY,trojan particles,smart particle aerosols,nanosuspension,bioadhesive nanoparticles,inhalation aerosols,LATEX-PARTICLES,ADULT-RATS,NANOPARTICLES,SIZE,PHAGOCYTOSIS,DEPOSITION},
  language     = {eng},
  number       = {2},
  pages        = {166--174},
  title        = {Nanotechnology and pharmaceutical inhalation aerosols},
  url          = {http://nopr.niscair.res.in/handle/123456789/5741},
  volume       = {45},
  year         = {2007},
}

Chicago
Patel, Ashok, and Pradeep R Vavia. 2007. “Nanotechnology and Pharmaceutical Inhalation Aerosols.” Indian Journal of Experimental Biology 45 (2): 166–174.
APA
Patel, A., & Vavia, P. R. (2007). Nanotechnology and pharmaceutical inhalation aerosols. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 45(2), 166–174.
Vancouver
1.
Patel A, Vavia PR. Nanotechnology and pharmaceutical inhalation aerosols. INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY. 2007;45(2):166–74.
MLA
Patel, Ashok, and Pradeep R Vavia. “Nanotechnology and Pharmaceutical Inhalation Aerosols.” INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY 45.2 (2007): 166–174. Print.