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A role for the root cap in root branching revealed by the non-auxin probe naxillin

(2012) NATURE CHEMICAL BIOLOGY. 8(9). p.798-805
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Biotechnology for a sustainable economy (Bio-Economy)
Abstract
The acquisition of water and nutrients by plant roots is a fundamental aspect of agriculture and strongly depends on root architecture. Root branching and expansion of the root system is achieved through the development of lateral roots and is to a large extent controlled by the plant hormone auxin. However, the pleiotropic effects of auxin or auxin-like molecules on root systems complicate the study of lateral root development. Here we describe a small-molecule screen in Arabidopsis thaliana that identified naxillin as what is to our knowledge the first non-auxin-like molecule that promotes root branching. By using naxillin as a chemical tool, we identified a new function for root cap-specific conversion of the auxin precursor indole-3-butyric acid into the active auxin indole-3-acetic acid and uncovered the involvement of the root cap in root branching. Delivery of an auxin precursor in peripheral tissues such as the root cap might represent an important mechanism shaping root architecture.
Keywords
GENE, AUX/IAA PROTEINS, PLANT DEVELOPMENT, MULTIFUNCTIONAL PROTEIN, ARABIDOPSIS-THALIANA, BOX PROTEIN TIR1, PEROXISOMAL BETA-OXIDATION, PRECURSOR INDOLE-3-BUTYRIC ACID, IDENTIFICATION, DEGRADATION

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Citation

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MLA
De Rybel, Bert, Dominique Audenaert, Wei Xuan, et al. “A Role for the Root Cap in Root Branching Revealed by the Non-auxin Probe Naxillin.” NATURE CHEMICAL BIOLOGY 8.9 (2012): 798–805. Print.
APA
De Rybel, B., Audenaert, D., Xuan, W., Overvoorde, P., Strader, L. C., Kepinski, S., Hoye, R., et al. (2012). A role for the root cap in root branching revealed by the non-auxin probe naxillin. NATURE CHEMICAL BIOLOGY, 8(9), 798–805.
Chicago author-date
De Rybel, Bert, Dominique Audenaert, Wei Xuan, Paul Overvoorde, Lucia C Strader, Stefan Kepinski, Rebecca Hoye, et al. 2012. “A Role for the Root Cap in Root Branching Revealed by the Non-auxin Probe Naxillin.” Nature Chemical Biology 8 (9): 798–805.
Chicago author-date (all authors)
De Rybel, Bert, Dominique Audenaert, Wei Xuan, Paul Overvoorde, Lucia C Strader, Stefan Kepinski, Rebecca Hoye, Ronald Brisbois, Boris Parizot, Steffen Vanneste, Xing Liu, Alison Gilday, Ian A Graham, Long Nguyen, Leentje Jansen, Maria Njo, Dirk Inzé, Bonnie Bartel, and Tom Beeckman. 2012. “A Role for the Root Cap in Root Branching Revealed by the Non-auxin Probe Naxillin.” Nature Chemical Biology 8 (9): 798–805.
Vancouver
1.
De Rybel B, Audenaert D, Xuan W, Overvoorde P, Strader LC, Kepinski S, et al. A role for the root cap in root branching revealed by the non-auxin probe naxillin. NATURE CHEMICAL BIOLOGY. 2012;8(9):798–805.
IEEE
[1]
B. De Rybel et al., “A role for the root cap in root branching revealed by the non-auxin probe naxillin,” NATURE CHEMICAL BIOLOGY, vol. 8, no. 9, pp. 798–805, 2012.
@article{3005414,
  abstract     = {The acquisition of water and nutrients by plant roots is a fundamental aspect of agriculture and strongly depends on root architecture. Root branching and expansion of the root system is achieved through the development of lateral roots and is to a large extent controlled by the plant hormone auxin. However, the pleiotropic effects of auxin or auxin-like molecules on root systems complicate the study of lateral root development. Here we describe a small-molecule screen in Arabidopsis thaliana that identified naxillin as what is to our knowledge the first non-auxin-like molecule that promotes root branching. By using naxillin as a chemical tool, we identified a new function for root cap-specific conversion of the auxin precursor indole-3-butyric acid into the active auxin indole-3-acetic acid and uncovered the involvement of the root cap in root branching. Delivery of an auxin precursor in peripheral tissues such as the root cap might represent an important mechanism shaping root architecture.},
  author       = {De Rybel, Bert and Audenaert, Dominique and Xuan, Wei and Overvoorde, Paul and Strader, Lucia C and Kepinski, Stefan and Hoye, Rebecca and Brisbois, Ronald and Parizot, Boris and Vanneste, Steffen and Liu, Xing and Gilday, Alison and Graham, Ian A and Nguyen, Long and Jansen, Leentje and Njo, Maria and Inzé, Dirk and Bartel, Bonnie and Beeckman, Tom},
  issn         = {1552-4450},
  journal      = {NATURE CHEMICAL BIOLOGY},
  keywords     = {GENE,AUX/IAA PROTEINS,PLANT DEVELOPMENT,MULTIFUNCTIONAL PROTEIN,ARABIDOPSIS-THALIANA,BOX PROTEIN TIR1,PEROXISOMAL BETA-OXIDATION,PRECURSOR INDOLE-3-BUTYRIC ACID,IDENTIFICATION,DEGRADATION},
  language     = {eng},
  number       = {9},
  pages        = {798--805},
  title        = {A role for the root cap in root branching revealed by the non-auxin probe naxillin},
  url          = {http://dx.doi.org/10.1038/NCHEMBIO.1044},
  volume       = {8},
  year         = {2012},
}

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