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Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents

(2004) ANAESTHESIA. 59(6). p.584-589
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Abstract
Two new generation carbon dioxide absorbents, DragerSorb(R) Free and Amsorb(R) Plus, were studied in vitro for formation of compound A or carbon monoxide, during minimal gas flow (500 ml.min(-1)) with sevoflurane or desflurane. Compound A was assessed by gas chromatography/mass spectrometry and carbon monoxide with continuous infrared spectrometry. Fresh and dehydrated absorbents were studied. Mean (SD) time till exhaustion (inspiratory carbon dioxide concentration greater than or equal to 1 kPa) with fresh absorbents was longer with DragerSorb(R) Free (1233 (55) min) than with Amsorb(R) Plus (1025 (55) min; p < 0.01). For both absorbents, values of compound A were < 1 ppm and therefore below clinically significant levels, but were up to 0.25 ppm higher with DragerSorb(R) Free than with Amsorb(R) Plus. Using dehydrated absorbents, values of compound A were about 50% lower than with fresh absorbents and were identical for DragerSorb(R) Free and Amsorb(R) Plus. With dehydrated absorbents, no detectable carbon monoxide was found with desflurane.
Keywords
absorption, carbon dioxide, anaesthetics, inhalation, sevoflurane, desflurane, compound A, carbon monoxide, SODA LIME, SEVOFLURANE ANESTHESIA, ABSORPTION CAPACITY, DEGRADATION, DESFLURANE, AMSORB(R), BREAKDOWN, SWINE

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MLA
Struys, Michel, MPLA Bouche, Georges Rolly, et al. “Production of Compound A and Carbon Monoxide in Circle Systems : an in Vitro Comparison of Two Carbon Dioxide Absorbents.” ANAESTHESIA 59.6 (2004): 584–589. Print.
APA
Struys, M., Bouche, M., Rolly, G., Vandevivere, Y., Dyzers, D., Goeteyn, W., Versichelen, L., et al. (2004). Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents. ANAESTHESIA, 59(6), 584–589. Presented at the Annual meeting of the American Society of Anaesthesiologists.
Chicago author-date
Struys, Michel, MPLA Bouche, Georges Rolly, YDI Vandevivere, Dorine Dyzers, Wim Goeteyn, Linda Versichelen, Jan Van Bocxlaer, and Eric Mortier. 2004. “Production of Compound A and Carbon Monoxide in Circle Systems : an in Vitro Comparison of Two Carbon Dioxide Absorbents.” Anaesthesia 59 (6): 584–589.
Chicago author-date (all authors)
Struys, Michel, MPLA Bouche, Georges Rolly, YDI Vandevivere, Dorine Dyzers, Wim Goeteyn, Linda Versichelen, Jan Van Bocxlaer, and Eric Mortier. 2004. “Production of Compound A and Carbon Monoxide in Circle Systems : an in Vitro Comparison of Two Carbon Dioxide Absorbents.” Anaesthesia 59 (6): 584–589.
Vancouver
1.
Struys M, Bouche M, Rolly G, Vandevivere Y, Dyzers D, Goeteyn W, et al. Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents. ANAESTHESIA. 2004;59(6):584–9.
IEEE
[1]
M. Struys et al., “Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents,” ANAESTHESIA, vol. 59, no. 6, pp. 584–589, 2004.
@article{300490,
  abstract     = {Two new generation carbon dioxide absorbents, DragerSorb(R) Free and Amsorb(R) Plus, were studied in vitro for formation of compound A or carbon monoxide, during minimal gas flow (500 ml.min(-1)) with sevoflurane or desflurane. Compound A was assessed by gas chromatography/mass spectrometry and carbon monoxide with continuous infrared spectrometry. Fresh and dehydrated absorbents were studied. Mean (SD) time till exhaustion (inspiratory carbon dioxide concentration greater than or equal to 1 kPa) with fresh absorbents was longer with DragerSorb(R) Free (1233 (55) min) than with Amsorb(R) Plus (1025 (55) min; p < 0.01). For both absorbents, values of compound A were < 1 ppm and therefore below clinically significant levels, but were up to 0.25 ppm higher with DragerSorb(R) Free than with Amsorb(R) Plus. Using dehydrated absorbents, values of compound A were about 50% lower than with fresh absorbents and were identical for DragerSorb(R) Free and Amsorb(R) Plus. With dehydrated absorbents, no detectable carbon monoxide was found with desflurane.},
  author       = {Struys, Michel and Bouche, MPLA and Rolly, Georges and Vandevivere, YDI and Dyzers, Dorine and Goeteyn, Wim and Versichelen, Linda and Van Bocxlaer, Jan and Mortier, Eric},
  issn         = {0003-2409},
  journal      = {ANAESTHESIA},
  keywords     = {absorption,carbon dioxide,anaesthetics,inhalation,sevoflurane,desflurane,compound A,carbon monoxide,SODA LIME,SEVOFLURANE ANESTHESIA,ABSORPTION CAPACITY,DEGRADATION,DESFLURANE,AMSORB(R),BREAKDOWN,SWINE},
  language     = {eng},
  location     = {San Francisco, CA, USA},
  number       = {6},
  pages        = {584--589},
  title        = {Production of compound A and carbon monoxide in circle systems : an in vitro comparison of two carbon dioxide absorbents},
  url          = {http://dx.doi.org/10.1111/j.1365-2044.2004.03704.x},
  volume       = {59},
  year         = {2004},
}

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