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A local maximum in gibberellin levels regulates maize leaf growth by spatial control of cell division

(2012) CURRENT BIOLOGY. 22(13). p.1183-1187
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Biotechnology for a sustainable economy (Bio-Economy)
Abstract
Plant growth rate is largely determined by the transition between the successive phases of cell division and expansion [1]. A key role for hormone signaling in determining this transition was inferred from genetic approaches and transcriptome analysis in the Arabidopsis root tip [2-5]. We used the developmental gradient at the maize leaf base as a model to study this transition, because it allows a direct comparison between endogenous hormone concentrations and the transitions between dividing, expanding, and mature tissue. Concentrations of auxin and cytokinins are highest in dividing tissues, whereas bioactive gibberellins (GAs) show a peak at the transition zone between the division and expansion zone. Combined metabolic and transcriptomic profiling revealed that this GA maximum is established by GA biosynthesis in the division zone (DZ) and active GA catabolism at the onset of the expansion zone. Mutants defective in GA synthesis and signaling, and transgenic plants overproducing GAs, demonstrate that altering GA levels specifically affects the size of the DZ, resulting in proportional changes in organ growth rates. This work thereby provides a novel molecular mechanism for the regulation of the transition from cell division to expansion that controls organ growth and size.
Keywords
ZEA-MAYS, ARABIDOPSIS ROOT, CYCLE PROGRESSION, ROOT-GROWTH, PLANT DEVELOPMENT, GENES, PROLIFERATION, EXPRESSION, MODULATORS, ACID

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Chicago
Nelissen, Hilde, Bart Rymen, Yusuke Jikumaru, Kirin Demuynck, Maria Van Lijsebettens, Yuji Kamiya, Dirk Inzé, and Gerrit Beemster. 2012. “A Local Maximum in Gibberellin Levels Regulates Maize Leaf Growth by Spatial Control of Cell Division.” Current Biology 22 (13): 1183–1187.
APA
Nelissen, H., Rymen, B., Jikumaru, Y., Demuynck, K., Van Lijsebettens, M., Kamiya, Y., Inzé, D., et al. (2012). A local maximum in gibberellin levels regulates maize leaf growth by spatial control of cell division. CURRENT BIOLOGY, 22(13), 1183–1187.
Vancouver
1.
Nelissen H, Rymen B, Jikumaru Y, Demuynck K, Van Lijsebettens M, Kamiya Y, et al. A local maximum in gibberellin levels regulates maize leaf growth by spatial control of cell division. CURRENT BIOLOGY. 2012;22(13):1183–7.
MLA
Nelissen, Hilde, Bart Rymen, Yusuke Jikumaru, et al. “A Local Maximum in Gibberellin Levels Regulates Maize Leaf Growth by Spatial Control of Cell Division.” CURRENT BIOLOGY 22.13 (2012): 1183–1187. Print.
@article{2974124,
  abstract     = {Plant growth rate is largely determined by the transition between the successive phases of cell division and expansion [1]. A key role for hormone signaling in determining this transition was inferred from genetic approaches and transcriptome analysis in the Arabidopsis root tip [2-5]. We used the developmental gradient at the maize leaf base as a model to study this transition, because it allows a direct comparison between endogenous hormone concentrations and the transitions between dividing, expanding, and mature tissue. Concentrations of auxin and cytokinins are highest in dividing tissues, whereas bioactive gibberellins (GAs) show a peak at the transition zone between the division and expansion zone. Combined metabolic and transcriptomic profiling revealed that this GA maximum is established by GA biosynthesis in the division zone (DZ) and active GA catabolism at the onset of the expansion zone. Mutants defective in GA synthesis and signaling, and transgenic plants overproducing GAs, demonstrate that altering GA levels specifically affects the size of the DZ, resulting in proportional changes in organ growth rates. This work thereby provides a novel molecular mechanism for the regulation of the transition from cell division to expansion that controls organ growth and size.},
  author       = {Nelissen, Hilde and Rymen, Bart and Jikumaru, Yusuke and Demuynck, Kirin and Van Lijsebettens, Maria and Kamiya, Yuji and Inz{\'e}, Dirk and Beemster, Gerrit},
  issn         = {0960-9822},
  journal      = {CURRENT BIOLOGY},
  keyword      = {ZEA-MAYS,ARABIDOPSIS ROOT,CYCLE PROGRESSION,ROOT-GROWTH,PLANT DEVELOPMENT,GENES,PROLIFERATION,EXPRESSION,MODULATORS,ACID},
  language     = {eng},
  number       = {13},
  pages        = {1183--1187},
  title        = {A local maximum in gibberellin levels regulates maize leaf growth by spatial control of cell division},
  url          = {http://dx.doi.org/10.1016/j.cub.2012.04.065},
  volume       = {22},
  year         = {2012},
}

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