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Tertiary lymphoid organs in infection and autoimmunity

(2012) TRENDS IN IMMUNOLOGY. 33(6). p.297-305
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Ghent researchers on unfolded proteins in inflammatory disease (GROUP-ID)
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Ghent researchers on unfolded proteins in inflammatory disease (GROUP-ID)
Abstract
The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation. This review focuses on the molecular mechanisms of TLO formation and maintenance, the controversies surrounding the nature of the inducing events, and the functions of these structures in infection, transplantation and autoimmunity.
Keywords
CHRONIC INFLAMMATION, RHEUMATOID-ARTHRITIS, DENDRITIC CELLS, NAIVE T-CELLS, TISSUE-INDUCER CELLS, PROGRESSIVE MULTIPLE-SCLEROSIS, NONOBESE DIABETIC MICE, LYMPHOTOXIN-BETA-RECEPTOR, TUMOR-NECROSIS-FACTOR, FIBROBLASTIC RETICULAR CELLS

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Citation

Please use this url to cite or link to this publication:

Chicago
Neyt, Katrijn, Frédéric Perros, Corine H GeurtsvanKessel, Hamida Hammad, and Bart Lambrecht. 2012. “Tertiary Lymphoid Organs in Infection and Autoimmunity.” Trends in Immunology 33 (6): 297–305.
APA
Neyt, Katrijn, Perros, F., GeurtsvanKessel, C. H., Hammad, H., & Lambrecht, B. (2012). Tertiary lymphoid organs in infection and autoimmunity. TRENDS IN IMMUNOLOGY, 33(6), 297–305.
Vancouver
1.
Neyt K, Perros F, GeurtsvanKessel CH, Hammad H, Lambrecht B. Tertiary lymphoid organs in infection and autoimmunity. TRENDS IN IMMUNOLOGY. 2012;33(6):297–305.
MLA
Neyt, Katrijn, Frédéric Perros, Corine H GeurtsvanKessel, et al. “Tertiary Lymphoid Organs in Infection and Autoimmunity.” TRENDS IN IMMUNOLOGY 33.6 (2012): 297–305. Print.
@article{2968125,
  abstract     = {The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation. This review focuses on the molecular mechanisms of TLO formation and maintenance, the controversies surrounding the nature of the inducing events, and the functions of these structures in infection, transplantation and autoimmunity.},
  author       = {Neyt, Katrijn and Perros, Fr{\'e}d{\'e}ric and GeurtsvanKessel, Corine H and Hammad, Hamida and Lambrecht, Bart},
  issn         = {1471-4906},
  journal      = {TRENDS IN IMMUNOLOGY},
  keyword      = {CHRONIC INFLAMMATION,RHEUMATOID-ARTHRITIS,DENDRITIC CELLS,NAIVE T-CELLS,TISSUE-INDUCER CELLS,PROGRESSIVE MULTIPLE-SCLEROSIS,NONOBESE DIABETIC MICE,LYMPHOTOXIN-BETA-RECEPTOR,TUMOR-NECROSIS-FACTOR,FIBROBLASTIC RETICULAR CELLS},
  language     = {eng},
  number       = {6},
  pages        = {297--305},
  title        = {Tertiary lymphoid organs in infection and autoimmunity},
  url          = {http://dx.doi.org/10.1016/j.it.2012.04.006},
  volume       = {33},
  year         = {2012},
}

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