Impaired filtering of irrelevant information in depression: an ERP study
- Author
- Max Owens, Ernst Koster (UGent) and Nazanin Derakshan
- Organization
- Abstract
- Behavioural findings have led to proposals that difficulties in attention and concentration in depression may have their roots in fundamental inhibitory impairments for irrelevant information. These impairments may be associated with reduced capacity to actively maintain relevant information to facilitate goadirected behaviour. In light of mixed data from behavioural studies, the current study using direct neural measurement, examines whether dysphoric individuals show poor filtering of irrelevant information and reduced working memory (WM) capacity for relevant information. Consistent with previous research, a sustained evenrelated potential (ERP) asymmetry, termed contralateral delay activity (CDA), was observed to be sensitive to WM capacity and the efficient filtering of irrelevant information from visual WM. We found a strong positive correlation between the efficiency of filtering irrelevant items and visual WM capacity. Specifically, dysphoric participants were poor at filtering irrelevant information, and showed reduced WM capacity relative to high capacity non-dysphoric participants. Results support the hypothesis that impaired inhibition is a central feature of dysphoria and are discussed within the framework of cognitive and neurophysiological models of depression.
- Keywords
- INDEPENDENT COMPONENT ANALYSIS, WORKING-MEMORY CAPACITY, EVENT-RELATED POTENTIALS, ATTENTIONAL CONTROL, COGNITIVE CONTROL, INDIVIDUAL-DIFFERENCES, PREFRONTAL CORTEX, MAJOR DEPRESSION, INHIBITION, TASK, attentional control, depression, inhibition, working memory capacity, contra similar to lateral delay activity, filtering efficiency
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Citation
Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-2958713
- Chicago
- Owens, Max, Ernst Koster, and Nazanin Derakshan. 2012. “Impaired Filtering of Irrelevant Information in Depression: An ERP Study.” Social Cognitive and Affective Neuroscience 7 (7): 752–763.
- APA
- Owens, M., Koster, E., & Derakshan, N. (2012). Impaired filtering of irrelevant information in depression: an ERP study. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 7(7), 752–763.
- Vancouver
- 1.Owens M, Koster E, Derakshan N. Impaired filtering of irrelevant information in depression: an ERP study. SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE. 2012;7(7):752–63.
- MLA
- Owens, Max, Ernst Koster, and Nazanin Derakshan. “Impaired Filtering of Irrelevant Information in Depression: An ERP Study.” SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE 7.7 (2012): 752–763. Print.
@article{2958713,
abstract = {Behavioural findings have led to proposals that difficulties in attention and concentration in depression may have their roots in fundamental inhibitory impairments for irrelevant information. These impairments may be associated with reduced capacity to actively maintain relevant information to facilitate goadirected behaviour. In light of mixed data from behavioural studies, the current study using direct neural measurement, examines whether dysphoric individuals show poor filtering of irrelevant information and reduced working memory (WM) capacity for relevant information. Consistent with previous research, a sustained evenrelated potential (ERP) asymmetry, termed contralateral delay activity (CDA), was observed to be sensitive to WM capacity and the efficient filtering of irrelevant information from visual WM. We found a strong positive correlation between the efficiency of filtering irrelevant items and visual WM capacity. Specifically, dysphoric participants were poor at filtering irrelevant information, and showed reduced WM capacity relative to high capacity non-dysphoric participants. Results support the hypothesis that impaired inhibition is a central feature of dysphoria and are discussed within the framework of cognitive and neurophysiological models of depression.},
author = {Owens, Max and Koster, Ernst and Derakshan, Nazanin},
issn = {1749-5016},
journal = {SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE},
keywords = {INDEPENDENT COMPONENT ANALYSIS,WORKING-MEMORY CAPACITY,EVENT-RELATED POTENTIALS,ATTENTIONAL CONTROL,COGNITIVE CONTROL,INDIVIDUAL-DIFFERENCES,PREFRONTAL CORTEX,MAJOR DEPRESSION,INHIBITION,TASK,attentional control,depression,inhibition,working memory capacity,contra similar to lateral delay activity,filtering efficiency},
language = {eng},
number = {7},
pages = {752--763},
title = {Impaired filtering of irrelevant information in depression: an ERP study},
volume = {7},
year = {2012},
}