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Signaling networks in cancer: an interview with Christian Gespach

Olivier De Wever UGent (2011) INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 55(7-9). p.713-718
abstract
The dynamic, innovative temperament of Christian Gespach is ideally suited to unraveling some aspects of the complex molecular networks connected with signal transduction, cancer progression and treatment. He is one of the pioneers who opened, in the early 1980s, new insights into the signaling mechanisms of G-protein coupled receptor (GPCR) activation, desensitization, internalisation and crosstalks. Twenty five years later and in collaboration with Gespach, IPSEN pharmaceuticals designed pan-inhibitors of GPCR signaling, targeting G alpha subunits in breast cancer progression and other epithelial cancers. Creativity is of vital importance to understand signal transduction pathways engaged in cancer cell motility, invasion and drug resistance. Christian Gespach has published more than 200 papers in cancer research, a true signal transduction tale.
Please use this url to cite or link to this publication:
author
organization
year
type
misc (editorialMaterial)
publication status
published
subject
keyword
molecular network, interview, GPCR, motility, VASOACTIVE-INTESTINAL-PEPTIDE, LARGE T-ONCOGENE, EPITHELIAL-CELLS, COLON-CANCER, CYCLIC-AMP, INVASION, BREAST, OXALIPLATIN, PROGRESSION, METASTASIS
in
INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
Int. J. Dev. Biol.
volume
55
issue
7-9
pages
713 - 718
Web of Science type
Editorial Material
Web of Science id
000299655900006
JCR category
DEVELOPMENTAL BIOLOGY
JCR impact factor
2.823 (2011)
JCR rank
19/40 (2011)
JCR quartile
2 (2011)
ISSN
0214-6282
DOI
10.1387/ijdb.113381ow
language
English
UGent publication?
yes
classification
V
copyright statement
I have transferred the copyright for this publication to the publisher
id
2941500
handle
http://hdl.handle.net/1854/LU-2941500
date created
2012-06-28 13:40:17
date last changed
2012-07-10 14:26:28
@misc{2941500,
  abstract     = {The dynamic, innovative temperament of Christian Gespach is ideally suited to unraveling some aspects of the complex molecular networks connected with signal transduction, cancer progression and treatment. He is one of the pioneers who opened, in the early 1980s, new insights into the signaling mechanisms of G-protein coupled receptor (GPCR) activation, desensitization, internalisation and crosstalks. Twenty five years later and in collaboration with Gespach, IPSEN pharmaceuticals designed pan-inhibitors of GPCR signaling, targeting G alpha subunits in breast cancer progression and other epithelial cancers. Creativity is of vital importance to understand signal transduction pathways engaged in cancer cell motility, invasion and drug resistance. Christian Gespach has published more than 200 papers in cancer research, a true signal transduction tale.},
  author       = {De Wever, Olivier},
  issn         = {0214-6282},
  keyword      = {molecular network,interview,GPCR,motility,VASOACTIVE-INTESTINAL-PEPTIDE,LARGE T-ONCOGENE,EPITHELIAL-CELLS,COLON-CANCER,CYCLIC-AMP,INVASION,BREAST,OXALIPLATIN,PROGRESSION,METASTASIS},
  language     = {eng},
  number       = {7-9},
  pages        = {713--718},
  series       = {INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY},
  title        = {Signaling networks in cancer: an interview with Christian Gespach},
  url          = {http://dx.doi.org/10.1387/ijdb.113381ow},
  volume       = {55},
  year         = {2011},
}

Chicago
De Wever, Olivier. 2011. “Signaling Networks in Cancer: An Interview with Christian Gespach.” International Journal of Developmental Biology.
APA
De Wever, O. (2011). Signaling networks in cancer: an interview with Christian Gespach. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY.
Vancouver
1.
De Wever O. Signaling networks in cancer: an interview with Christian Gespach. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY. 2011. p. 713–8.
MLA
De Wever, Olivier. “Signaling Networks in Cancer: An Interview with Christian Gespach.” INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY 2011 : 713–718. Print.