Ghent University Academic Bibliography

Advanced

Rapid effects of dietary fish oil on peroxisomes in mouse liver

Dirk De Craemer UGent, Frank Roels UGent and Christiane Vand den Branden (1993) EUROPEAN JOURNAL OF MORPHOLOGY. 31(1-2). p.77-81
abstract
We investigated hepatic catalase activity, and morphologic and morphometric alterations of hepatocellular peroxisomes after catalase cytochemistry, in mice given a diet supplemented with 10% Beromegan(R), a commercial fish oil preparation, for up to three days. Fish oil is rich in docosahexaenoic acid (C22:6 (n-3)) and in eicosapentaenoic acid (20:5 (n-3)). Hepatic catalase activity showed a gradual increase in mice fed this diet, being significantly increased (136+/-10 U(B)/g liver) after three days when compared top controls (85+/-11 U(B)/g liver). Light microscopy indicated an increase in peroxisomal staining and peroxisomal proliferation. The latter observation was confirmed by ultrastructural morphometry: number, volume density and surface density of the peroxisomes were more than doubled after a three day diet containing fish oil. Peroxisomal size was not changed. These alterations are suggestive for an increased peroxisomal metabolism induced by a diet rich in poly-unsaturated fatty acids.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (proceedingsPaper)
publication status
published
subject
keyword
RETROCONVERSION, METABOLISM, CELLS, FATTY-ACIDS, BETA-OXIDATION, RAT-LIVER, POLYUNSATURATED FATTY ACIDS, MORPHOMETRY, CATALASE ACTIVITY, CATALASE CYTOCHEMISTRY, 22-6(N-3)
journal title
EUROPEAN JOURNAL OF MORPHOLOGY
Eur. J. Morphol.
volume
31
issue
1-2
pages
77 - 81
conference name
JOINT MEETING OF THE DUTCH AND BELGIAN SOCIETIES FOR ELECTRON MICROSCOPY AND THE BELGIAN SOC FOR CELL BIOLOGY : BIOMEDICAL COMMUNICATIONS
conference location
Antwerp, Belgium
conference start
1992-12-10
conference end
1992-12-11
Web of Science type
Proceedings Paper
ISSN
0924-3860
language
English
UGent publication?
no
classification
A1
id
235205
handle
http://hdl.handle.net/1854/LU-235205
date created
2004-05-24 13:25:00
date last changed
2010-03-12 09:42:35
@article{235205,
  abstract     = {We investigated hepatic catalase activity, and morphologic and morphometric alterations of hepatocellular peroxisomes after catalase cytochemistry, in mice given a diet supplemented with 10\% Beromegan(R), a commercial fish oil preparation, for up to three days. Fish oil is rich in docosahexaenoic acid (C22:6 (n-3)) and in eicosapentaenoic acid (20:5 (n-3)). Hepatic catalase activity showed a gradual increase in mice fed this diet, being significantly increased (136+/-10 U(B)/g liver) after three days when compared top controls (85+/-11 U(B)/g liver). Light microscopy indicated an increase in peroxisomal staining and peroxisomal proliferation. The latter observation was confirmed by ultrastructural morphometry: number, volume density and surface density of the peroxisomes were more than doubled after a three day diet containing fish oil. Peroxisomal size was not changed. These alterations are suggestive for an increased peroxisomal metabolism induced by a diet rich in poly-unsaturated fatty acids.},
  author       = {De Craemer, Dirk and Roels, Frank and Vand den Branden, Christiane},
  issn         = {0924-3860},
  journal      = {EUROPEAN JOURNAL OF MORPHOLOGY},
  keyword      = {RETROCONVERSION,METABOLISM,CELLS,FATTY-ACIDS,BETA-OXIDATION,RAT-LIVER,POLYUNSATURATED FATTY ACIDS,MORPHOMETRY,CATALASE ACTIVITY,CATALASE CYTOCHEMISTRY,22-6(N-3)},
  language     = {eng},
  location     = {Antwerp, Belgium},
  number       = {1-2},
  pages        = {77--81},
  title        = {Rapid effects of dietary fish oil on peroxisomes in mouse liver},
  volume       = {31},
  year         = {1993},
}

Chicago
De Craemer, Dirk, Frank Roels, and Christiane Vand den Branden. 1993. “Rapid Effects of Dietary Fish Oil on Peroxisomes in Mouse Liver.” European Journal of Morphology 31 (1-2): 77–81.
APA
De Craemer, D., Roels, F., & Vand den Branden, C. (1993). Rapid effects of dietary fish oil on peroxisomes in mouse liver. EUROPEAN JOURNAL OF MORPHOLOGY, 31(1-2), 77–81. Presented at the JOINT MEETING OF THE DUTCH AND BELGIAN SOCIETIES FOR ELECTRON MICROSCOPY AND THE BELGIAN SOC FOR CELL BIOLOGY : BIOMEDICAL COMMUNICATIONS.
Vancouver
1.
De Craemer D, Roels F, Vand den Branden C. Rapid effects of dietary fish oil on peroxisomes in mouse liver. EUROPEAN JOURNAL OF MORPHOLOGY. 1993;31(1-2):77–81.
MLA
De Craemer, Dirk, Frank Roels, and Christiane Vand den Branden. “Rapid Effects of Dietary Fish Oil on Peroxisomes in Mouse Liver.” EUROPEAN JOURNAL OF MORPHOLOGY 31.1-2 (1993): 77–81. Print.