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Positron emission tomographic studies of changes in cerebral blood flow and oxygen metabolism in neuroleptic malignant syndrome

Jacques De Reuck, Jozef Van Aken (UGent) , William Van Landegem (UGent) and Francis Colardyn (UGent)
(1991) EUROPEAN NEUROLOGY. 31(1). p.1-6
Author
Organization
Abstract
Three patients with neuroleptic malignant syndrome were studied by positron emission tomography (PET), using the steady-state technique with C15O2 and (O2.)-O-15. In 2 patients the PET examination was repeated after resolution of the syndrome. In 2 patients, under treatment with bromocriptine, high blood flow and oxygen metabolism were demonstrated in the striatum, cerebellum and occipital cerebral cortex during the neuroleptic malignant phase, showing that not only the dopaminergic system is disturbed but also other neurotransmitter systems are involved. In the 3rd case the PET scan findings were not as conclusive.
Keywords
NEUROLEPTIC MALIGNANT SYNDROME, BROMOCRIPTINE, POSITRON EMISSION TOMOGRAPHY, PARKINSONS-DISEASE, BROMOCRIPTINE, WITHDRAWAL, AMANTADINE, DANTROLENE, FREQUENCY, LEVODOPA, THERAPY, DRUGS

Citation

Please use this url to cite or link to this publication:

MLA
De Reuck, Jacques, et al. “Positron Emission Tomographic Studies of Changes in Cerebral Blood Flow and Oxygen Metabolism in Neuroleptic Malignant Syndrome.” EUROPEAN NEUROLOGY, vol. 31, no. 1, 1991, pp. 1–6, doi:10.1159/000116625.
APA
De Reuck, J., Van Aken, J., Van Landegem, W., & Colardyn, F. (1991). Positron emission tomographic studies of changes in cerebral blood flow and oxygen metabolism in neuroleptic malignant syndrome. EUROPEAN NEUROLOGY, 31(1), 1–6. https://doi.org/10.1159/000116625
Chicago author-date
De Reuck, Jacques, Jozef Van Aken, William Van Landegem, and Francis Colardyn. 1991. “Positron Emission Tomographic Studies of Changes in Cerebral Blood Flow and Oxygen Metabolism in Neuroleptic Malignant Syndrome.” EUROPEAN NEUROLOGY 31 (1): 1–6. https://doi.org/10.1159/000116625.
Chicago author-date (all authors)
De Reuck, Jacques, Jozef Van Aken, William Van Landegem, and Francis Colardyn. 1991. “Positron Emission Tomographic Studies of Changes in Cerebral Blood Flow and Oxygen Metabolism in Neuroleptic Malignant Syndrome.” EUROPEAN NEUROLOGY 31 (1): 1–6. doi:10.1159/000116625.
Vancouver
1.
De Reuck J, Van Aken J, Van Landegem W, Colardyn F. Positron emission tomographic studies of changes in cerebral blood flow and oxygen metabolism in neuroleptic malignant syndrome. EUROPEAN NEUROLOGY. 1991;31(1):1–6.
IEEE
[1]
J. De Reuck, J. Van Aken, W. Van Landegem, and F. Colardyn, “Positron emission tomographic studies of changes in cerebral blood flow and oxygen metabolism in neuroleptic malignant syndrome,” EUROPEAN NEUROLOGY, vol. 31, no. 1, pp. 1–6, 1991.
@article{225647,
  abstract     = {{Three patients with neuroleptic malignant syndrome were studied by positron emission tomography (PET), using the steady-state technique with C15O2 and (O2.)-O-15. In 2 patients the PET examination was repeated after resolution of the syndrome. In 2 patients, under treatment with bromocriptine, high blood flow and oxygen metabolism were demonstrated in the striatum, cerebellum and occipital cerebral cortex during the neuroleptic malignant phase, showing that not only the dopaminergic system is disturbed but also other neurotransmitter systems are involved. In the 3rd case the PET scan findings were not as conclusive.}},
  author       = {{De Reuck, Jacques and Van Aken, Jozef and Van Landegem, William and Colardyn, Francis}},
  issn         = {{0014-3022}},
  journal      = {{EUROPEAN NEUROLOGY}},
  keywords     = {{NEUROLEPTIC MALIGNANT SYNDROME,BROMOCRIPTINE,POSITRON EMISSION TOMOGRAPHY,PARKINSONS-DISEASE,BROMOCRIPTINE,WITHDRAWAL,AMANTADINE,DANTROLENE,FREQUENCY,LEVODOPA,THERAPY,DRUGS}},
  language     = {{eng}},
  number       = {{1}},
  pages        = {{1--6}},
  title        = {{Positron emission tomographic studies of changes in cerebral blood flow and oxygen metabolism in neuroleptic malignant syndrome}},
  url          = {{http://doi.org/10.1159/000116625}},
  volume       = {{31}},
  year         = {{1991}},
}
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