Advanced search

Hepatitis A booster vaccination : is there a need?

(2003) LANCET. 362(9389). p.1065-1071
Author
Organization
Abstract
Hepatitis A is one of the most common vaccine-preventable infectious diseases in the world. Effective vaccines against hepatitis A have been available since 1992, and they provide long-term immunity against the infection. However, there is no worldwide consensus on how long protection will last or whether there will be a need for hepatitis A virus (HAV) booster vaccinations in the future. In most countries, booster-vaccination policy is guided by manufacturers' recommendations, national authorities, or both. In June, 2002, a panel of international experts met to review the long-term immunogenicity and protection conferred by HAV vaccine in different population groups. Data have shown that after a full primary vaccination course, protective antibody amounts persist beyond 10 years in healthy individuals, and underlying immune memory provides protection far beyond the duration of anti-HAV antibodies. The group concluded that there is no evidence to lend support to HAV booster vaccination after a full primary vaccination course in a healthy individual. However, further investigations are needed before deciding if boosters can be omitted in special patient-groups.
Keywords
LONG-TERM PERSISTENCE, CHRONIC LIVER-DISEASE, FOLLOW-UP, CHILDHOOD VACCINATION, HEALTHY-CHILDREN, VIRUS-VACCINE, B VACCINES, IMMUNOGENICITY, SAFETY, IMMUNIZATION

Citation

Please use this url to cite or link to this publication:

Chicago
Van Damme, P, J Banatvala, O Fay, S Iwarson, B McMahon, Koen Van Herck, D Shouval, et al. 2003. “Hepatitis A Booster Vaccination : Is There a Need?” Lancet 362 (9389): 1065–1071.
APA
Van Damme, P, Banatvala, J., Fay, O., Iwarson, S., McMahon, B., Van Herck, K., Shouval, D., et al. (2003). Hepatitis A booster vaccination : is there a need? LANCET, 362(9389), 1065–1071.
Vancouver
1.
Van Damme P, Banatvala J, Fay O, Iwarson S, McMahon B, Van Herck K, et al. Hepatitis A booster vaccination : is there a need? LANCET. 2003;362(9389):1065–71.
MLA
Van Damme, P, J Banatvala, O Fay, et al. “Hepatitis A Booster Vaccination : Is There a Need?” LANCET 362.9389 (2003): 1065–1071. Print.
@article{217882,
  abstract     = {Hepatitis A is one of the most common vaccine-preventable infectious diseases in the world. Effective vaccines against hepatitis A have been available since 1992, and they provide long-term immunity against the infection. However, there is no worldwide consensus on how long protection will last or whether there will be a need for hepatitis A virus (HAV) booster vaccinations in the future. In most countries, booster-vaccination policy is guided by manufacturers' recommendations, national authorities, or both. In June, 2002, a panel of international experts met to review the long-term immunogenicity and protection conferred by HAV vaccine in different population groups. Data have shown that after a full primary vaccination course, protective antibody amounts persist beyond 10 years in healthy individuals, and underlying immune memory provides protection far beyond the duration of anti-HAV antibodies. The group concluded that there is no evidence to lend support to HAV booster vaccination after a full primary vaccination course in a healthy individual. However, further investigations are needed before deciding if boosters can be omitted in special patient-groups.},
  author       = {Van Damme, P and Banatvala, J and Fay, O and Iwarson, S and McMahon, B and Van Herck, Koen and Shouval, D and Bonanni, P and Connor, B and Cooksley, G and Leroux-Roels, Geert and Von Sonnenburg, F},
  issn         = {0140-6736},
  journal      = {LANCET},
  keyword      = {LONG-TERM PERSISTENCE,CHRONIC LIVER-DISEASE,FOLLOW-UP,CHILDHOOD VACCINATION,HEALTHY-CHILDREN,VIRUS-VACCINE,B VACCINES,IMMUNOGENICITY,SAFETY,IMMUNIZATION},
  language     = {eng},
  number       = {9389},
  pages        = {1065--1071},
  title        = {Hepatitis A booster vaccination : is there a need?},
  url          = {http://dx.doi.org/10.1016/S0140-6736(03)14418-2},
  volume       = {362},
  year         = {2003},
}

Altmetric
View in Altmetric
Web of Science
Times cited: