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Design of a static full-ring multi-pinhole collimator for brain SPECT

Karen Van Audenhaege UGent, Roel Van Holen UGent, Karel Deprez UGent, Joel S Karp, Scott Metzler and Stefaan Vandenberghe UGent (2011) IEEE Nuclear Science Symposium Conference Record. p.4393-4397
abstract
In clinical practice, brain SPECT is mostly performed using a dual-head SPECT scanner with fan-beam or parallel-beam collimators rotating around the patient's head. The resolution of such a system is typically about 6-8 mm, which is rather poor to image the complex structures of the human brain. We developed a non-rotating multi-pinhole collimator for brain SPECT imaging with a resolution of 4 mm. A full-ring geometry allows for complete transaxial sampling. This enables the use of a stationary collimator. The collimator is a tungsten ring with two rows of pinholes. Each pinhole can individually be opened or closed with shutters. A sequence of shutter movements is performed to obtain an acquisition setup that simulates a rotational movement. The collimator is designed for the LaPET system (a PET detector ring made of 24 LaBr 3 detectors) and is optimized to maximize the system performance, resulting in a collimator radius of 145 mm and a pinhole diameter of 2 mm. This system has a sensitivity that is 4 times lower than a dual-head system with LEHR parallel-beam collimators. However, the resolution is 2 times better, a trade-off that is supported by Muehllehner [1]. Monte-Carlo simulated projections of a resolution phantom are successfully reconstructed and the resulting image shows that a resolution of 4 mm is indeed achieved.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
keyword
collimator, system design, SPECT, instrumentation, Imaging
in
IEEE Nuclear Science Symposium Conference Record
issue title
2011 IEEE Nuclear science symposium and medical imaging conference (NSS/MIC)
pages
4393 - 4397
publisher
IEEE
place of publication
Piscataway, NJ, USA
conference name
2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC 2011)
conference location
Valencia, Spain
conference start
2011-10-23
conference end
2011-10-29
Web of Science type
Proceedings Paper
Web of Science id
000304755604134
ISSN
1082-3654
ISBN
9781467301206
DOI
10.1109/NSSMIC.2011.6153847
project
The integrative neuroscience of behavioral control (Neuroscience)
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
2139070
handle
http://hdl.handle.net/1854/LU-2139070
date created
2012-06-11 14:21:12
date last changed
2013-02-27 09:07:14
@inproceedings{2139070,
  abstract     = {In clinical practice, brain SPECT is mostly performed using a dual-head SPECT scanner with fan-beam or parallel-beam collimators rotating around the patient's head. The resolution of such a system is typically about 6-8 mm, which is rather poor to image the complex structures of the human brain. We developed a non-rotating multi-pinhole collimator for brain SPECT imaging with a resolution of 4 mm. A full-ring geometry allows for complete transaxial sampling. This enables the use of a stationary collimator. The collimator is a tungsten ring with two rows of pinholes. Each pinhole can individually be opened or closed with shutters. A sequence of shutter movements is performed to obtain an acquisition setup that simulates a rotational movement. The collimator is designed for the LaPET system (a PET detector ring made of 24 LaBr 3 detectors) and is optimized to maximize the system performance, resulting in a collimator radius of 145 mm and a pinhole diameter of 2 mm. This system has a sensitivity that is 4 times lower than a dual-head system with LEHR parallel-beam collimators. However, the resolution is 2 times better, a trade-off that is supported by Muehllehner [1]. Monte-Carlo simulated projections of a resolution phantom are successfully reconstructed and the resulting image shows that a resolution of 4 mm is indeed achieved.},
  author       = {Van Audenhaege, Karen and Van Holen, Roel and Deprez, Karel and Karp, Joel S and Metzler, Scott and Vandenberghe, Stefaan},
  booktitle    = {IEEE Nuclear Science Symposium Conference Record},
  isbn         = {9781467301206},
  issn         = {1082-3654},
  keyword      = {collimator,system design,SPECT,instrumentation,Imaging},
  language     = {eng},
  location     = {Valencia, Spain},
  pages        = {4393--4397},
  publisher    = {IEEE},
  title        = {Design of a static full-ring multi-pinhole collimator for brain SPECT},
  url          = {http://dx.doi.org/10.1109/NSSMIC.2011.6153847},
  year         = {2011},
}

Chicago
Van Audenhaege, Karen, Roel Van Holen, Karel Deprez, Joel S Karp, Scott Metzler, and Stefaan Vandenberghe. 2011. “Design of a Static Full-ring Multi-pinhole Collimator for Brain SPECT.” In IEEE Nuclear Science Symposium Conference Record, 4393–4397. Piscataway, NJ, USA: IEEE.
APA
Van Audenhaege, K., Van Holen, R., Deprez, K., Karp, J. S., Metzler, S., & Vandenberghe, S. (2011). Design of a static full-ring multi-pinhole collimator for brain SPECT. IEEE Nuclear Science Symposium Conference Record (pp. 4393–4397). Presented at the 2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC 2011), Piscataway, NJ, USA: IEEE.
Vancouver
1.
Van Audenhaege K, Van Holen R, Deprez K, Karp JS, Metzler S, Vandenberghe S. Design of a static full-ring multi-pinhole collimator for brain SPECT. IEEE Nuclear Science Symposium Conference Record. Piscataway, NJ, USA: IEEE; 2011. p. 4393–7.
MLA
Van Audenhaege, Karen, Roel Van Holen, Karel Deprez, et al. “Design of a Static Full-ring Multi-pinhole Collimator for Brain SPECT.” IEEE Nuclear Science Symposium Conference Record. Piscataway, NJ, USA: IEEE, 2011. 4393–4397. Print.