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Quality of life and its association with prevalences and therapeutic control of cardiovascular risk factors in CHD patients

Delphine De Smedt UGent, Kornelia Kotseva, Andrzej Pajak, Lieven Annemans UGent and Dirk De Bacquer UGent (2012) EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 19(suppl. 1). p.S101-S101
abstract
Purpose and methods : The EUROASPIRE III survey (European Action on Secondary and Primary Prevention by Intervention to Reduce Events) was carried out during 2006-2007 in 22 European countries. Within each country, consecutive patients ≥18 years of age and less than 80 years of age at the time of identification, with first or recurrent diagnosis for CHD (CABG, PTCA, AMI, Ischaemia) were identified retrospectively from clinical registers, hospital discharge lists or other sources. Patients were interviewed and examined at least 6 months after their acute coronary event. Quality of life of each patient was measured by use of standardized questionnaires, among other the EuroQol-5D (EQ-5D) questionnaire. The main objective of this study was to assess the distribution of EQ-5D scores in CHD patients across countries and to identify factors responsible for the variation between patients. Results : According to the EQ-5D instrument a third of patients perceived no pain or discomfort, 42.6% were not anxious or depressed and about half of the patients reported no problem in walking (47.6%) or performing their usual activities (54.7%). Regarding self-care, 85.8% of patients did not report any problems. EQ-5D scores varied substantially between countries with mean values for men ranging from 0.67 (Slovenia) to 0.86 (Italy), whereas for women the index score ranges from 0.57 (Russian Federation) to 0.79 (Italy). Results showed an inverse relationship with age with a mean score of 0.81 and 0.71 in men and women resp. below 50 years or age and a mean score of 0.74 and 0.66 in men and women resp. aged 70 years or older. Regression analyses identified diabetes, current smoking, lack of regular exercise and cardiovascular history as the most important factors associated with quality of life scores. Concerning the therapeutic control of risk factors and their relation with quality of life, results show a positive association between smoking cessation and quality of life in men, and a positive association between controlled hypertension and quality of life in women. No significant relation was found with controlled hyperlipidaemia or diabetes. Conclusion : Overall, a large heterogeneity was observed in EQ-5D values between countries and patient groups. There seems to be a strong association between quality of life and cardiovascular risk factors such as diabetes, smoking, lack of exercise and cardiovascular history. Additionally, therapeutic control of risk factors such as smoking and hypertension seems more optimal in patients with a higher quality of life.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
in
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
Eur. J. Prev. Cardiol.
volume
19
issue
suppl. 1
article number
abstract P537
pages
S101 - S101
conference name
EuroPRevent 2012
conference location
Dublin, Ireland
conference start
2012-05-03
conference end
2012-05-05
ISSN
2047-4873
DOI
10.1177/2047487312448011
language
English
UGent publication?
yes
classification
C3
id
2133964
handle
http://hdl.handle.net/1854/LU-2133964
date created
2012-06-06 10:52:05
date last changed
2016-12-21 15:40:58
@inproceedings{2133964,
  abstract     = {Purpose and methods : The EUROASPIRE III survey (European Action on Secondary and Primary Prevention by Intervention to Reduce Events) was carried out during 2006-2007 in 22 European countries. Within each country, consecutive patients \ensuremath{\geq}18 years of age and less than 80 years of age at the time of identification, with first or recurrent diagnosis for CHD (CABG, PTCA, AMI, Ischaemia) were identified retrospectively from clinical registers, hospital discharge lists or other sources. Patients were interviewed and examined at least 6 months after their acute coronary event.  Quality of life of each patient was measured by use of standardized questionnaires, among other the EuroQol-5D (EQ-5D) questionnaire. The main objective of this study was to assess the distribution of  EQ-5D scores in CHD patients across countries and to identify factors responsible for the variation between patients. 
Results : According to the EQ-5D instrument a third of patients perceived no pain or discomfort, 42.6\% were not anxious or depressed and about half of the patients reported no problem in walking (47.6\%) or performing their usual activities (54.7\%). Regarding self-care, 85.8\% of patients did not report any problems.  EQ-5D scores varied substantially between countries with mean values for men ranging from 0.67 (Slovenia) to 0.86 (Italy), whereas for women the index score ranges from 0.57 (Russian Federation) to 0.79 (Italy). Results showed an inverse relationship with age with a mean score of 0.81 and 0.71 in men and women resp. below 50 years or age and a mean score of 0.74 and 0.66 in men and women resp. aged 70 years or older. Regression analyses identified diabetes, current smoking, lack of regular exercise and cardiovascular history as the most important factors associated with quality of life scores. Concerning the therapeutic control of risk factors and their relation with quality of life, results show a positive association between smoking cessation and quality of life in men, and a positive association between controlled hypertension and quality of life in women. No significant relation was found with controlled hyperlipidaemia or diabetes.
Conclusion : Overall, a large heterogeneity was observed in EQ-5D values between countries and patient groups. There seems to be a strong association between quality of life and cardiovascular risk factors such as diabetes, smoking, lack of exercise and cardiovascular history. Additionally, therapeutic control of risk factors such as smoking and hypertension seems more optimal in patients with a higher quality of life.},
  articleno    = {abstract P537},
  author       = {De Smedt, Delphine and Kotseva, Kornelia and  Pajak, Andrzej and Annemans, Lieven and De Bacquer, Dirk},
  booktitle    = {EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY},
  issn         = {2047-4873},
  language     = {eng},
  location     = {Dublin, Ireland},
  number       = {suppl. 1},
  pages        = {abstract P537:S101--abstract P537:S101},
  title        = {Quality of life and its association with prevalences and therapeutic control of cardiovascular risk factors in CHD patients},
  url          = {http://dx.doi.org/10.1177/2047487312448011},
  volume       = {19},
  year         = {2012},
}

Chicago
De Smedt, Delphine, Kornelia Kotseva, Andrzej Pajak, Lieven Annemans, and Dirk De Bacquer. 2012. “Quality of Life and Its Association with Prevalences and Therapeutic Control of Cardiovascular Risk Factors in CHD Patients.” In European Journal of Preventive Cardiology, 19:S101–S101.
APA
De Smedt, D., Kotseva, K., Pajak, A., Annemans, L., & De Bacquer, D. (2012). Quality of life and its association with prevalences and therapeutic control of cardiovascular risk factors in CHD patients. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY (Vol. 19, pp. S101–S101). Presented at the EuroPRevent 2012.
Vancouver
1.
De Smedt D, Kotseva K, Pajak A, Annemans L, De Bacquer D. Quality of life and its association with prevalences and therapeutic control of cardiovascular risk factors in CHD patients. EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY. 2012. p. S101–S101.
MLA
De Smedt, Delphine, Kornelia Kotseva, Andrzej Pajak, et al. “Quality of Life and Its Association with Prevalences and Therapeutic Control of Cardiovascular Risk Factors in CHD Patients.” European Journal of Preventive Cardiology. Vol. 19. 2012. S101–S101. Print.