Advanced search
1 file | 471.31 KB Add to list

Enzymes for the biocatalytic production of rare sugars

Koen Beerens (UGent) , Tom Desmet (UGent) and Wim Soetaert (UGent)
Author
Organization
Project
Abstract
Carbohydrates are much more than just a source of energy as they also mediate a variety of recognition processes that are central to human health. As such, saccharides can be applied in the food and pharmaceutical industries to stimulate our immune system (e.g., prebiotics), to control diabetes (e.g., low-calorie sweeteners), or as building blocks for anticancer and antiviral drugs (e.g., l-nucleosides). Unfortunately, only a small number of all possible monosaccharides are found in nature in sufficient amounts to allow their commercial exploitation. Consequently, so-called rare sugars have to be produced by (bio)chemical processes starting from cheap and widely available substrates. Three enzyme classes that can be used for rare sugar production are keto-aldol isomerases, epimerases, and oxidoreductases. In this review, the recent developments in rare sugar production with these biocatalysts are discussed.
Keywords
Rare sugars, Biocatalysis, Epimerase, Isomerase, Polyol dehydrogenase, L-ARABINOSE ISOMERASE, D-TAGATOSE 3-EPIMERASE, L-RHAMNOSE ISOMERASE, L-RIBOSE ISOMERASE, SITE-DIRECTED MUTAGENESIS, BACILLUS-PALLIDUS Y25, D-LYXOSE ISOMERASE, D-XYLOSE ISOMERASE, SP STRAIN DL-28, D-ALLOSE

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 471.31 KB

Citation

Please use this url to cite or link to this publication:

MLA
Beerens, Koen, et al. “Enzymes for the Biocatalytic Production of Rare Sugars.” JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, vol. 39, no. 6, 2012, pp. 823–34, doi:10.1007/s10295-012-1089-x.
APA
Beerens, K., Desmet, T., & Soetaert, W. (2012). Enzymes for the biocatalytic production of rare sugars. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 39(6), 823–834. https://doi.org/10.1007/s10295-012-1089-x
Chicago author-date
Beerens, Koen, Tom Desmet, and Wim Soetaert. 2012. “Enzymes for the Biocatalytic Production of Rare Sugars.” JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 39 (6): 823–34. https://doi.org/10.1007/s10295-012-1089-x.
Chicago author-date (all authors)
Beerens, Koen, Tom Desmet, and Wim Soetaert. 2012. “Enzymes for the Biocatalytic Production of Rare Sugars.” JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 39 (6): 823–834. doi:10.1007/s10295-012-1089-x.
Vancouver
1.
Beerens K, Desmet T, Soetaert W. Enzymes for the biocatalytic production of rare sugars. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY. 2012;39(6):823–34.
IEEE
[1]
K. Beerens, T. Desmet, and W. Soetaert, “Enzymes for the biocatalytic production of rare sugars,” JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, vol. 39, no. 6, pp. 823–834, 2012.
@article{2121904,
  abstract     = {{Carbohydrates are much more than just a source of energy as they also mediate a variety of recognition processes that are central to human health. As such, saccharides can be applied in the food and pharmaceutical industries to stimulate our immune system (e.g., prebiotics), to control diabetes (e.g., low-calorie sweeteners), or as building blocks for anticancer and antiviral drugs (e.g., l-nucleosides). Unfortunately, only a small number of all possible monosaccharides are found in nature in sufficient amounts to allow their commercial exploitation. Consequently, so-called rare sugars have to be produced by (bio)chemical processes starting from cheap and widely available substrates. Three enzyme classes that can be used for rare sugar production are keto-aldol isomerases, epimerases, and oxidoreductases. In this review, the recent developments in rare sugar production with these biocatalysts are discussed.}},
  author       = {{Beerens, Koen and Desmet, Tom and Soetaert, Wim}},
  issn         = {{1367-5435}},
  journal      = {{JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY}},
  keywords     = {{Rare sugars,Biocatalysis,Epimerase,Isomerase,Polyol dehydrogenase,L-ARABINOSE ISOMERASE,D-TAGATOSE 3-EPIMERASE,L-RHAMNOSE ISOMERASE,L-RIBOSE ISOMERASE,SITE-DIRECTED MUTAGENESIS,BACILLUS-PALLIDUS Y25,D-LYXOSE ISOMERASE,D-XYLOSE ISOMERASE,SP STRAIN DL-28,D-ALLOSE}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{823--834}},
  title        = {{Enzymes for the biocatalytic production of rare sugars}},
  url          = {{http://doi.org/10.1007/s10295-012-1089-x}},
  volume       = {{39}},
  year         = {{2012}},
}

Altmetric
View in Altmetric
Web of Science
Times cited: