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Worldwide screening for canine hip dysplasia: where are we now?

(2012) VETERINARY SURGERY. 41(1). p.10-19
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Organization
Abstract
Objective: To critically review the different screening systems used for canine hip dysplasia (CHD) and their impact on the prevalence of the disease. Study design: Critical literature review. Methods: Literature search through PubMed (November 1959-October 2011) and the Orthopedic Foundation for Animals (OFA), Federation Cynologique Internationale (FCI), British Veterinary Association/Kennel Club (BVA/KC), and Pennsylvania Hip Improvement Program (PennHIP) websites. Results: The OFA, FCI, and BVA/KC screening methods, which use the hip-extended radiographic projection, have had relatively minor success on CHD prevalence. These screening approaches are prone to conflicting data regarding interobserver agreement. The PennHIP and Dorsolateral Subluxation (DLS) systems, both distraction methods, have not reported on prevalence but seem to be important heritable traits in genomic screening of dysplastic dogs. Conclusion: A shift towards genome screening yields a promising future combating CHD, although further investigation towards fine-mapping in the search for genes, responsible for CHD, is necessary.
Keywords
GERMAN-SHEPHERD DOGS, DEGENERATIVE JOINT DISEASE, QUANTITATIVE TRAIT LOCI, CAUDOLATERAL CURVILINEAR OSTEOPHYTE, LABRADOR-RETRIEVERS, DISTRACTION INDEX, DORSOLATERAL SUBLUXATION, INTEROBSERVER AGREEMENT, COXOFEMORAL JOINT, BREEDING VALUES

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Citation

Please use this url to cite or link to this publication:

Chicago
Verhoeven, Geert, Ruth Fortrie, Bernadette Van Ryssen, and Frank Coopman. 2012. “Worldwide Screening for Canine Hip Dysplasia: Where Are We Now?” Veterinary Surgery 41 (1): 10–19.
APA
Verhoeven, Geert, Fortrie, R., Van Ryssen, B., & Coopman, F. (2012). Worldwide screening for canine hip dysplasia: where are we now? VETERINARY SURGERY, 41(1), 10–19.
Vancouver
1.
Verhoeven G, Fortrie R, Van Ryssen B, Coopman F. Worldwide screening for canine hip dysplasia: where are we now? VETERINARY SURGERY. 2012;41(1):10–9.
MLA
Verhoeven, Geert, Ruth Fortrie, Bernadette Van Ryssen, et al. “Worldwide Screening for Canine Hip Dysplasia: Where Are We Now?” VETERINARY SURGERY 41.1 (2012): 10–19. Print.
@article{2116490,
  abstract     = {Objective: To critically review the different screening systems used for canine hip dysplasia (CHD) and their impact on the prevalence of the disease. 
Study design: Critical literature review. 
Methods: Literature search through PubMed (November 1959-October 2011) and the Orthopedic Foundation for Animals (OFA), Federation Cynologique Internationale (FCI), British Veterinary Association/Kennel Club (BVA/KC), and Pennsylvania Hip Improvement Program (PennHIP) websites. 
Results: The OFA, FCI, and BVA/KC screening methods, which use the hip-extended radiographic projection, have had relatively minor success on CHD prevalence. These screening approaches are prone to conflicting data regarding interobserver agreement. The PennHIP and Dorsolateral Subluxation (DLS) systems, both distraction methods, have not reported on prevalence but seem to be important heritable traits in genomic screening of dysplastic dogs. 
Conclusion: A shift towards genome screening yields a promising future combating CHD, although further investigation towards fine-mapping in the search for genes, responsible for CHD, is necessary.},
  author       = {Verhoeven, Geert and Fortrie, Ruth and Van Ryssen, Bernadette and Coopman, Frank},
  issn         = {0161-3499},
  journal      = {VETERINARY SURGERY},
  keyword      = {GERMAN-SHEPHERD DOGS,DEGENERATIVE JOINT DISEASE,QUANTITATIVE TRAIT LOCI,CAUDOLATERAL CURVILINEAR OSTEOPHYTE,LABRADOR-RETRIEVERS,DISTRACTION INDEX,DORSOLATERAL SUBLUXATION,INTEROBSERVER AGREEMENT,COXOFEMORAL JOINT,BREEDING VALUES},
  language     = {eng},
  number       = {1},
  pages        = {10--19},
  title        = {Worldwide screening for canine hip dysplasia: where are we now?},
  url          = {http://dx.doi.org/10.1111/j.1532-950X.2011.00929.x},
  volume       = {41},
  year         = {2012},
}

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