Ghent University Academic Bibliography

@article{2112408,
  abstract     = {Space travel is a major challenge for human beings. Especially, the mechanisms through which space conditions might alter animal development have been questioned for a long time. The two major physical stress factors that are of relevance in this context are space radiation and weightlessness. While it has been extensively shown that high doses of ionizing radiation induce deleterious effects on embryonic development, so far, little is known about the potential harmful effects of radiation in combination with microgravity on the developing organism. In the present study, we investigated the effects of simulated microgravity on irradiated STO mouse fetal fibroblast cells using a random positioning machine (RPM). Radiation-induced cell cycle changes were not affected when cells were subjected to simulated microgravity for 24 h. Moreover, no morphological differences were observed in irradiated samples exposed to simulated microgravity compared to cells that were exclusively irradiated. However, microgravity simulation significantly decreased the level of apoptosis at all doses as measured by caspase-3 activity and it prevented cells from undergoing radiation-induced size increase up to 1 Gy.},
  author       = {Beck, Micha{\"e}l and Tabury, Kevin and Moreels, Marjan and Jacquet, Paul and Van Oostveldt, Patric and De Vos, Winnok and Baatout, Sarah},
  issn         = {1107-3756},
  journal      = {INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE},
  keyword      = {simulated microgravity,X-rays,fetal mouse fibroblasts,DNA damage,cell cycle arrest,apoptosis,RANDOM-POSITIONING MACHINE,IONIZING-RADIATION,CELLULAR-RESPONSE,X-IRRADIATION,DNA-REPAIR,CELLS,LYMPHOCYTES,SPACE,EXPRESSION},
  language     = {eng},
  number       = {2},
  pages        = {309--313},
  title        = {Simulated microgravity decreases apoptosis in fetal fibroblasts},
  url          = {http://dx.doi.org/10.3892/ijmm.2012.1001},
  volume       = {30},
  year         = {2012},
}

Chicago

Beck, Michaël, Kevin Tabury, Marjan Moreels, Paul Jacquet, Patric Van Oostveldt, Winnok De Vos, and Sarah Baatout. 2012. “Simulated Microgravity Decreases Apoptosis in Fetal Fibroblasts.” International Journal of Molecular Medicine 30 (2): 309–313.

APA

Beck, Michaël, Tabury, K., Moreels, M., Jacquet, P., Van Oostveldt, P., De Vos, W., & Baatout, S. (2012). Simulated microgravity decreases apoptosis in fetal fibroblasts. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 30(2), 309–313.

Vancouver

1.

Beck M, Tabury K, Moreels M, Jacquet P, Van Oostveldt P, De Vos W, et al. Simulated microgravity decreases apoptosis in fetal fibroblasts. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE. 2012;30(2):309–13.

MLA

Beck, Michaël, Kevin Tabury, Marjan Moreels, et al. “Simulated Microgravity Decreases Apoptosis in Fetal Fibroblasts.” INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE 30.2 (2012): 309–313. Print.