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Keep it in the subfamily: the conserved alphaherpesvirus US3 protein kinase

Matthias Deruelle (UGent) and Herman Favoreel (UGent)
(2011) JOURNAL OF GENERAL VIROLOGY. 92(1). p.18-30
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Abstract
The US3 protein kinase is conserved over the alphaherpesvirus subfamily. Increasing evidence shows that, although the kinase is generally not required for virus replication in cell culture, it plays a pivotal and in some cases an essential role in virus virulence in vivo. The US3 protein is a multifunctional serine/threonine kinase that is involved in viral gene expression, virion morphogenesis, remodelling the actin cytoskeleton and the evasion of several antiviral host responses. In the current review, both the well conserved and virus-specific functions of alphaherpesvirus US3 protein kinase orthologues will be discussed.
Keywords
HERPES-SIMPLEX-VIRUS, VARICELLA-ZOSTER-VIRUS, TRANSCRIPTIONAL REGULATORY PROTEIN, TO-CELL SPREAD, STRESS FIBER BREAKDOWN, EFFICIENT VIRAL GROWTH, OUTER NUCLEAR-MEMBRANE, MAREKS-DISEASE VIRUS, COMPLEX CLASS-I, PSEUDORABIES VIRUS

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Citation

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Chicago
Deruelle, Matthias, and Herman Favoreel. 2011. “Keep It in the Subfamily: The Conserved Alphaherpesvirus US3 Protein Kinase.” Journal of General Virology 92 (1): 18–30.
APA
Deruelle, M., & Favoreel, H. (2011). Keep it in the subfamily: the conserved alphaherpesvirus US3 protein kinase. JOURNAL OF GENERAL VIROLOGY, 92(1), 18–30.
Vancouver
1.
Deruelle M, Favoreel H. Keep it in the subfamily: the conserved alphaherpesvirus US3 protein kinase. JOURNAL OF GENERAL VIROLOGY. 2011;92(1):18–30.
MLA
Deruelle, Matthias, and Herman Favoreel. “Keep It in the Subfamily: The Conserved Alphaherpesvirus US3 Protein Kinase.” JOURNAL OF GENERAL VIROLOGY 92.1 (2011): 18–30. Print.
@article{2112365,
  abstract     = {The US3 protein kinase is conserved over the alphaherpesvirus subfamily. Increasing evidence shows that, although the kinase is generally not required for virus replication in cell culture, it plays a pivotal and in some cases an essential role in virus virulence in vivo. The US3 protein is a multifunctional serine/threonine kinase that is involved in viral gene expression, virion morphogenesis, remodelling the actin cytoskeleton and the evasion of several antiviral host responses. In the current review, both the well conserved and virus-specific functions of alphaherpesvirus US3 protein kinase orthologues will be discussed.},
  author       = {Deruelle, Matthias and Favoreel, Herman},
  issn         = {0022-1317},
  journal      = {JOURNAL OF GENERAL VIROLOGY},
  keyword      = {HERPES-SIMPLEX-VIRUS,VARICELLA-ZOSTER-VIRUS,TRANSCRIPTIONAL REGULATORY PROTEIN,TO-CELL SPREAD,STRESS FIBER BREAKDOWN,EFFICIENT VIRAL GROWTH,OUTER NUCLEAR-MEMBRANE,MAREKS-DISEASE VIRUS,COMPLEX CLASS-I,PSEUDORABIES VIRUS},
  language     = {eng},
  number       = {1},
  pages        = {18--30},
  title        = {Keep it in the subfamily: the conserved alphaherpesvirus US3 protein kinase},
  url          = {http://dx.doi.org/10.1099/vir.0.025593-0},
  volume       = {92},
  year         = {2011},
}

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