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Expression of beta(2)-integrin on monocytes and blood polymorphonuclear leukocytes in the periparturient period in dairy cows

Araceli Diez Fraile (UGent), Luc Duchateau (UGent), Evelyne Meyer (UGent) and Christian Burvenich (UGent)
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Abstract
The hypothesis that an altered expression of CD11/CD18 on bovine circulating monocytes, polymorphonuclear leukocytes (PMN), or both, contributes to an increased mastitis susceptibility in periparturient cows was tested. Expression of CD18 and CD11a, -b, -c on bovine monocytes and PMN were assessed in 8 Friesian-Holstein cows by flow cytometry from 2 wk before calving to 5 wk after calving. Minor changes in adhesion molecule expression levels were detected throughout the experimental period. Compared with PMN, monocytes exhibited an expression level that was similar for CD18, higher for CD11a and CD11c, but lower for CD11b. Differences in density may reflect the relative importance of these adhesion molecules on both leukocyte types. In this study, the decreased number of milk resident macrophages and PMN observed during the periparturient period could not be attributed to changes of CD11/CD18 levels on circulating leukocytes.
Keywords
CELL COUNTS, NEUTROPHILS, MAMMARY-GLAND, RECEPTOR EXPRESSION, ESCHERICHIA-COLI MASTITIS, ADHESION MOLECULES, SECRETIONS, INTEGRINS, ADHERENCE, EOSINOPHILS

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Chicago
Diez Fraile, Araceli, Luc Duchateau, Evelyne Meyer, and Christian Burvenich. 2003. “Expression of Beta(2)-integrin on Monocytes and Blood Polymorphonuclear Leukocytes in the Periparturient Period in Dairy Cows.” Canadian Journal of Veterinary Research-revue Canadienne De Recherche Veterinaire 67 (3): 235–238.
APA
Diez Fraile, A., Duchateau, L., Meyer, E., & Burvenich, C. (2003). Expression of beta(2)-integrin on monocytes and blood polymorphonuclear leukocytes in the periparturient period in dairy cows. CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE, 67(3), 235–238.
Vancouver
1.
Diez Fraile A, Duchateau L, Meyer E, Burvenich C. Expression of beta(2)-integrin on monocytes and blood polymorphonuclear leukocytes in the periparturient period in dairy cows. CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE. 2003;67(3):235–8.
MLA
Diez Fraile, Araceli, Luc Duchateau, Evelyne Meyer, et al. “Expression of Beta(2)-integrin on Monocytes and Blood Polymorphonuclear Leukocytes in the Periparturient Period in Dairy Cows.” CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE 67.3 (2003): 235–238. Print.
@article{209748,
  abstract     = {The hypothesis that an altered expression of CD11/CD18 on bovine circulating monocytes, polymorphonuclear leukocytes (PMN), or both, contributes to an increased mastitis susceptibility in periparturient cows was tested. Expression of CD18 and CD11a, -b, -c on bovine monocytes and PMN were assessed in 8 Friesian-Holstein cows by flow cytometry from 2 wk before calving to 5 wk after calving. Minor changes in adhesion molecule expression levels were detected throughout the experimental period. Compared with PMN, monocytes exhibited an expression level that was similar for CD18, higher for CD11a and CD11c, but lower for CD11b. Differences in density may reflect the relative importance of these adhesion molecules on both leukocyte types. In this study, the decreased number of milk resident macrophages and PMN observed during the periparturient period could not be attributed to changes of CD11/CD18 levels on circulating leukocytes.},
  author       = {Diez Fraile, Araceli and Duchateau, Luc and Meyer, Evelyne and Burvenich, Christian},
  issn         = {0830-9000},
  journal      = {CANADIAN JOURNAL OF VETERINARY RESEARCH-REVUE CANADIENNE DE RECHERCHE VETERINAIRE},
  keyword      = {CELL COUNTS,NEUTROPHILS,MAMMARY-GLAND,RECEPTOR EXPRESSION,ESCHERICHIA-COLI MASTITIS,ADHESION MOLECULES,SECRETIONS,INTEGRINS,ADHERENCE,EOSINOPHILS},
  language     = {eng},
  number       = {3},
  pages        = {235--238},
  title        = {Expression of beta(2)-integrin on monocytes and blood polymorphonuclear leukocytes in the periparturient period in dairy cows},
  url          = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC227060/pdf/20030700s00014p235.pdf/?tool=pmcentrez},
  volume       = {67},
  year         = {2003},
}

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