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Restrictive extraocular myopathy: a presenting feature of acromegaly

STEVEN HEIREMAN (UGent) , Christophe Delaey (UGent) , Ilse Claerhout (UGent) and CHRISTIAN DECOCK (UGent)
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Abstract
A 45-year-old man presented with binocular diplopia in primary gaze for 1 year. Orthoptic evaluation showed 10-prism diopter right eye hypotropia and 6-prism diopter right eye esotropia. The elevation and abduction of the right eye were mechanically restricted. This was associated with systemic features suggestive of acromegaly. Magnetic resonance imaging (MRI) of the brain demonstrated a pituitary macroadenoma. An elevated serum insulin-like growth factor I level and the failure of growth hormone suppression aft er an oral glucose load biochemically confirmed the diagnosis of acromegaly. Computed tomography (CT) of the orbit demonstrated bilateral symmetrical enlargement of the medial rectus and inferior rectus muscle bellies. All tests regarding Graves-Basedow disease were negative. Although rare, diplopia due to a restrictive extraocular myopathy could be the presenting symptom of acromegaly.
Keywords
restrictive myopathy, MUSCLE ENLARGEMENT, pituitary adenoma, extraocular myopathy, Acromegaly, diplopia

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Chicago
HEIREMAN, STEVEN, Christophe Delaey, Ilse Claerhout, and CHRISTIAN DECOCK. 2011. “Restrictive Extraocular Myopathy: a Presenting Feature of Acromegaly.” Indian Journal of Ophthalmology 59 (6): 517–519.
APA
HEIREMAN, S., Delaey, C., Claerhout, I., & DECOCK, C. (2011). Restrictive extraocular myopathy: a presenting feature of acromegaly. INDIAN JOURNAL OF OPHTHALMOLOGY, 59(6), 517–519.
Vancouver
1.
HEIREMAN S, Delaey C, Claerhout I, DECOCK C. Restrictive extraocular myopathy: a presenting feature of acromegaly. INDIAN JOURNAL OF OPHTHALMOLOGY. 2011;59(6):517–9.
MLA
HEIREMAN, STEVEN, Christophe Delaey, Ilse Claerhout, et al. “Restrictive Extraocular Myopathy: a Presenting Feature of Acromegaly.” INDIAN JOURNAL OF OPHTHALMOLOGY 59.6 (2011): 517–519. Print.
@article{2090572,
  abstract     = {A 45-year-old man presented with binocular diplopia in primary gaze for 1 year. Orthoptic evaluation showed 10-prism diopter right eye hypotropia and 6-prism diopter right eye esotropia. The elevation and abduction of the right eye were mechanically restricted. This was associated with systemic features suggestive of acromegaly. Magnetic resonance imaging (MRI) of the brain demonstrated a pituitary macroadenoma. An elevated serum insulin-like growth factor I level and the failure of growth hormone suppression aft er an oral glucose load biochemically confirmed the diagnosis of acromegaly. Computed tomography (CT) of the orbit demonstrated bilateral symmetrical enlargement of the medial rectus and inferior rectus muscle bellies. All tests regarding Graves-Basedow disease were negative. Although rare, diplopia due to a restrictive extraocular myopathy could be the presenting symptom of acromegaly.},
  author       = {HEIREMAN, STEVEN and Delaey, Christophe and Claerhout, Ilse and DECOCK, CHRISTIAN},
  issn         = {0301-4738},
  journal      = {INDIAN JOURNAL OF OPHTHALMOLOGY},
  keyword      = {restrictive myopathy,MUSCLE ENLARGEMENT,pituitary adenoma,extraocular myopathy,Acromegaly,diplopia},
  language     = {eng},
  number       = {6},
  pages        = {517--519},
  title        = {Restrictive extraocular myopathy: a presenting feature of acromegaly},
  url          = {http://dx.doi.org/10.4103/0301-4738.86330},
  volume       = {59},
  year         = {2011},
}

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