Advanced search
1 file | 202.19 KB Add to list

Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites

Author
Organization
Abstract
Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, alpha-zearalenol, beta-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.
Keywords
immunoaffinity columns, deoxynivalenol, VALIDATION, MYCOTOXINS, CLEANUP, Fusarium toxins, EGGS, MAIZE, zearalenone, cross-reactivity, multi analyte UPLC-MS/MS, conjugated mycotoxins, PERFORMANCE LIQUID-CHROMATOGRAPHY

Downloads

  • (...).pdf
    • full text
    • |
    • UGent only
    • |
    • PDF
    • |
    • 202.19 KB

Citation

Please use this url to cite or link to this publication:

MLA
Versilovskis, Aleksandrs, et al. “Cross-Reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-Conjugated Forms and Metabolites.” FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, vol. 28, no. 12, 2011, pp. 1687–93, doi:10.1080/19440049.2011.603364.
APA
Versilovskis, A., Huybrecht, B., Tangni, E., Pussemier, L., De Saeger, S., & Callebaut, A. (2011). Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 28(12), 1687–1693. https://doi.org/10.1080/19440049.2011.603364
Chicago author-date
Versilovskis, Aleksandrs, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger, and A Callebaut. 2011. “Cross-Reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-Conjugated Forms and Metabolites.” FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 28 (12): 1687–93. https://doi.org/10.1080/19440049.2011.603364.
Chicago author-date (all authors)
Versilovskis, Aleksandrs, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger, and A Callebaut. 2011. “Cross-Reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-Conjugated Forms and Metabolites.” FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 28 (12): 1687–1693. doi:10.1080/19440049.2011.603364.
Vancouver
1.
Versilovskis A, Huybrecht B, Tangni E, Pussemier L, De Saeger S, Callebaut A. Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 2011;28(12):1687–93.
IEEE
[1]
A. Versilovskis, B. Huybrecht, E. Tangni, L. Pussemier, S. De Saeger, and A. Callebaut, “Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites,” FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, vol. 28, no. 12, pp. 1687–1693, 2011.
@article{2079520,
  abstract     = {{Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, alpha-zearalenol, beta-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.}},
  author       = {{Versilovskis, Aleksandrs and Huybrecht, B and Tangni, EK and Pussemier, L and De Saeger, Sarah and Callebaut, A}},
  issn         = {{1944-0049}},
  journal      = {{FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT}},
  keywords     = {{immunoaffinity columns,deoxynivalenol,VALIDATION,MYCOTOXINS,CLEANUP,Fusarium toxins,EGGS,MAIZE,zearalenone,cross-reactivity,multi analyte UPLC-MS/MS,conjugated mycotoxins,PERFORMANCE LIQUID-CHROMATOGRAPHY}},
  language     = {{eng}},
  number       = {{12}},
  pages        = {{1687--1693}},
  title        = {{Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites}},
  url          = {{http://dx.doi.org/10.1080/19440049.2011.603364}},
  volume       = {{28}},
  year         = {{2011}},
}

Altmetric
View in Altmetric
Web of Science
Times cited: