Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites

Versilovskis, Aleksandrs; Huybrecht, B; Tangni, EK; Pussemier, L; De Saeger, Sarah; Callebaut, A

Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites

Aleksandrs Versilovskis UGent, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger UGent and A Callebaut (2011) FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 28(12). p.1687-1693

Mark

abstract: Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, alpha-zearalenol, beta-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.

Please use this url to cite or link to this publication: http://hdl.handle.net/1854/LU-2079520

author

Aleksandrs Versilovskis UGent, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger UGent and A Callebaut

organization

Department of Bio-analysis

year

2011

type

journalArticle (original)

publication status

published

subject

Chemistry

keyword

immunoaffinity columns, deoxynivalenol, VALIDATION, MYCOTOXINS, CLEANUP, Fusarium toxins, EGGS, MAIZE, zearalenone, cross-reactivity, multi analyte UPLC-MS/MS, conjugated mycotoxins, PERFORMANCE LIQUID-CHROMATOGRAPHY

journal title

FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT

Food Addit. Contam. Part A-Chem.

volume

issue

pages

1687 - 1693

Web of Science type

Article

Web of Science id

000298286300007

JCR category

FOOD SCIENCE & TECHNOLOGY

JCR impact factor

1.765 (2011)

JCR rank

42/128 (2011)

JCR quartile

2 (2011)

ISSN

1944-0049

DOI

10.1080/19440049.2011.603364

language

English

UGent publication?

yes

classification

copyright statement

I have transferred the copyright for this publication to the publisher

id

2079520

handle

http://hdl.handle.net/1854/LU-2079520

date created

2012-04-03 10:58:42

date last changed

2016-12-19 15:46:24

@article{2079520,
  abstract     = {Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, alpha-zearalenol, beta-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.},
  author       = {Versilovskis, Aleksandrs and Huybrecht, B and Tangni, EK and Pussemier, L and De Saeger, Sarah and Callebaut, A},
  issn         = {1944-0049},
  journal      = {FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE \& RISK ASSESSMENT},
  keyword      = {immunoaffinity columns,deoxynivalenol,VALIDATION,MYCOTOXINS,CLEANUP,Fusarium toxins,EGGS,MAIZE,zearalenone,cross-reactivity,multi analyte UPLC-MS/MS,conjugated mycotoxins,PERFORMANCE LIQUID-CHROMATOGRAPHY},
  language     = {eng},
  number       = {12},
  pages        = {1687--1693},
  title        = {Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites},
  url          = {http://dx.doi.org/10.1080/19440049.2011.603364},
  volume       = {28},
  year         = {2011},
}

Chicago: Versilovskis, Aleksandrs, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger, and A Callebaut. 2011. “Cross-reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-conjugated Forms and Metabolites.” Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment 28 (12): 1687–1693.
APA: Versilovskis, A., Huybrecht, B., Tangni, E., Pussemier, L., De Saeger, S., & Callebaut, A. (2011). Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 28(12), 1687–1693.
Vancouver: 1.
Versilovskis A, Huybrecht B, Tangni E, Pussemier L, De Saeger S, Callebaut A. Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 2011;28(12):1687–93.
MLA: Versilovskis, Aleksandrs, B Huybrecht, EK Tangni, et al. “Cross-reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-conjugated Forms and Metabolites.” FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 28.12 (2011): 1687–1693. Print.