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Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites

Aleksandrs Versilovskis UGent, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger UGent and A Callebaut (2011) FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 28(12). p.1687-1693
abstract
Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, alpha-zearalenol, beta-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
immunoaffinity columns, deoxynivalenol, VALIDATION, MYCOTOXINS, CLEANUP, Fusarium toxins, EGGS, MAIZE, zearalenone, cross-reactivity, multi analyte UPLC-MS/MS, conjugated mycotoxins, PERFORMANCE LIQUID-CHROMATOGRAPHY
journal title
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT
Food Addit. Contam. Part A-Chem.
volume
28
issue
12
pages
1687 - 1693
Web of Science type
Article
Web of Science id
000298286300007
JCR category
FOOD SCIENCE & TECHNOLOGY
JCR impact factor
1.765 (2011)
JCR rank
42/128 (2011)
JCR quartile
2 (2011)
ISSN
1944-0049
DOI
10.1080/19440049.2011.603364
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
2079520
handle
http://hdl.handle.net/1854/LU-2079520
date created
2012-04-03 10:58:42
date last changed
2012-04-12 13:10:18
@article{2079520,
  abstract     = {Seven commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns (IACs) were tested for cross-reactivity to conjugated forms (3-acetyl-deoxynivalenol, 15-acetyl-deoxynivalenol, DON-3-glucoside, DON-3-glucuronide, ZEN-glucosides, ZEN-glucuronide) and metabolites (de-epoxydeoxynivalenol, alpha-zearalenol, beta-zearalenol) and nivalenol (NIV), using a semi-quantitative multi-mycotoxin ultra-performance liquid chromatography-tandem mass spectrometry method. The DON IACs showed cross-reactivity for nearly all DON derivatives tested. The ZEN IACs showed limited cross-reactivity to some of the ZEN derivatives. The IACs were evaluated for their potential use as sample clean-up for mycotoxins in serum.},
  author       = {Versilovskis, Aleksandrs and Huybrecht, B and Tangni, EK and Pussemier, L and De Saeger, Sarah and Callebaut, A},
  issn         = {1944-0049},
  journal      = {FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE \& RISK ASSESSMENT},
  keyword      = {immunoaffinity columns,deoxynivalenol,VALIDATION,MYCOTOXINS,CLEANUP,Fusarium toxins,EGGS,MAIZE,zearalenone,cross-reactivity,multi analyte UPLC-MS/MS,conjugated mycotoxins,PERFORMANCE LIQUID-CHROMATOGRAPHY},
  language     = {eng},
  number       = {12},
  pages        = {1687--1693},
  title        = {Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites},
  url          = {http://dx.doi.org/10.1080/19440049.2011.603364},
  volume       = {28},
  year         = {2011},
}

Chicago
Versilovskis, Aleksandrs, B Huybrecht, EK Tangni, L Pussemier, Sarah De Saeger, and A Callebaut. 2011. “Cross-reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-conjugated Forms and Metabolites.” Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment 28 (12): 1687–1693.
APA
Versilovskis, A., Huybrecht, B., Tangni, E., Pussemier, L., De Saeger, S., & Callebaut, A. (2011). Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 28(12), 1687–1693.
Vancouver
1.
Versilovskis A, Huybrecht B, Tangni E, Pussemier L, De Saeger S, Callebaut A. Cross-reactivity of some commercially available deoxynivalenol (DON) and zearalenone (ZEN) immunoaffinity columns to DON- and ZEN-conjugated forms and metabolites. FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT. 2011;28(12):1687–93.
MLA
Versilovskis, Aleksandrs, B Huybrecht, EK Tangni, et al. “Cross-reactivity of Some Commercially Available Deoxynivalenol (DON) and Zearalenone (ZEN) Immunoaffinity Columns to DON- and ZEN-conjugated Forms and Metabolites.” FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT 28.12 (2011): 1687–1693. Print.