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Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study

(2011) TRANSPLANT INTERNATIONAL. 24(12). p.1239-1245
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Abstract
Patients with end-stage isolated polycystic liver disease (PCLD) suffer from incapacitating symptoms because of very large liver volumes. Liver transplantation (LT) is the only curative option. This study assesses the feasibility of LT in PCLD. We used the European Liver Transplant Registry (ELTR) database to extract demographics and outcomes of 58 PCLD patients. We used Kaplan-Meier survival analysis for survival rates. Severe abdominal pain (75%) was the most prominent symptom, while portal hypertension (35%) was the most common complication in PCLD. The explantation of the polycystic liver was extremely difficult in 38% of patients, because of presence of adhesions from prior therapy (17%). Karnofsky score following LT was 90%. The 1- and 5-year graft survival rate was 94.3% and 87.5%, while patient survival rate was 94.8% and 92.3%, respectively. Survival rates after LT for PCLD are good.
Keywords
FENESTRATION, MANAGEMENT, liver cyst, polycystic liver disease, liver transplantation, KIDNEY-TRANSPLANTATION, treatment, VOLUME, CYSTS

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Chicago
van Keimpema, Loes, Frederik Nevens, Rene Adam, Robert J Porte, Panagiotis Fikatas, Thomas Becker, Preben Kirkegaard, et al. 2011. “Excellent Survival After Liver Transplantation for Isolated Polycystic Liver Disease: An European Liver Transplant Registry Study.” Transplant International 24 (12): 1239–1245.
APA
van Keimpema, L., Nevens, F., Adam, R., Porte, R. J., Fikatas, P., Becker, T., Kirkegaard, P., et al. (2011). Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study. TRANSPLANT INTERNATIONAL, 24(12), 1239–1245.
Vancouver
1.
van Keimpema L, Nevens F, Adam R, Porte RJ, Fikatas P, Becker T, et al. Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study. TRANSPLANT INTERNATIONAL. 2011;24(12):1239–45.
MLA
van Keimpema, Loes, Frederik Nevens, Rene Adam, et al. “Excellent Survival After Liver Transplantation for Isolated Polycystic Liver Disease: An European Liver Transplant Registry Study.” TRANSPLANT INTERNATIONAL 24.12 (2011): 1239–1245. Print.
@article{2077401,
  abstract     = {Patients with end-stage isolated polycystic liver disease (PCLD) suffer from incapacitating symptoms because of very large liver volumes. Liver transplantation (LT) is the only curative option. This study assesses the feasibility of LT in PCLD. We used the European Liver Transplant Registry (ELTR) database to extract demographics and outcomes of 58 PCLD patients. We used Kaplan-Meier survival analysis for survival rates. Severe abdominal pain (75\%) was the most prominent symptom, while portal hypertension (35\%) was the most common complication in PCLD. The explantation of the polycystic liver was extremely difficult in 38\% of patients, because of presence of adhesions from prior therapy (17\%). Karnofsky score following LT was 90\%. The 1- and 5-year graft survival rate was 94.3\% and 87.5\%, while patient survival rate was 94.8\% and 92.3\%, respectively. Survival rates after LT for PCLD are good.},
  author       = {van Keimpema, Loes and Nevens, Frederik and Adam, Rene and Porte, Robert J and Fikatas, Panagiotis and Becker, Thomas and Kirkegaard, Preben and Metselaar, Herold J and Drenth, Joost PH and European Liver and Intestine Transplant Association (ELITA), the and Van Vlierberghe, Hans},
  issn         = {0934-0874},
  journal      = {TRANSPLANT INTERNATIONAL},
  keyword      = {FENESTRATION,MANAGEMENT,liver cyst,polycystic liver disease,liver transplantation,KIDNEY-TRANSPLANTATION,treatment,VOLUME,CYSTS},
  language     = {eng},
  number       = {12},
  pages        = {1239--1245},
  title        = {Excellent survival after liver transplantation for isolated polycystic liver disease: an European Liver Transplant Registry study},
  url          = {http://dx.doi.org/10.1111/j.1432-2277.2011.01360.x},
  volume       = {24},
  year         = {2011},
}

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