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Modulation of connexin signaling by bacterial pathogens and their toxins

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Abstract
Inherent to their pivotal tasks in the maintenance of cellular homeostasis, gap junctions, connexin hemichannels, and pannexin hemichannels are frequently involved in the dysregulation of this critical balance. The present paper specifically focuses on their roles in bacterial infection and disease. In particular, the reported biological outcome of clinically important bacteria including Escherichia coli, Shigella flexneri, Yersinia enterocolitica, Helicobacter pylori, Bordetella pertussis, Aggregatibacter actinomycetemcomitans, Pseudomonas aeruginosa, Citrobacter rodentium, Clostridium species, Streptococcus pneumoniae, and Staphylococcus aureus and their toxic products on connexin- and pannexin-related signaling in host cells is reviewed. Particular attention is paid to the underlying molecular mechanisms of these effects as well as to the actual biological relevance of these findings.
Keywords
Pannexin, Hemichannel, Connexin, Gap junction, Bacteria, Toxin, HELICOBACTER-PYLORI INFECTION, GAP-JUNCTION CHANNELS, TUMOR-NECROSIS-FACTOR, OF-THE-LITERATURE, MICROVASCULAR ENDOTHELIAL-CELLS, BORDETELLA-PERTUSSIS INFECTION, GASTRIC EPITHELIAL-CELLS, ESCHERICHIA-COLI, INTERCELLULAR COMMUNICATION, ACTINOBACILLUS-ACTINOMYCETEMCOMITANS

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Chicago
Ceelen, Liesbeth, Freddy Haesebrouck, Tamara Vanhaecke, Vera Rogiers, and Mathieu Vinken. 2011. “Modulation of Connexin Signaling by Bacterial Pathogens and Their Toxins.” Cellular and Molecular Life Sciences 68 (18): 3047–3064.
APA
Ceelen, Liesbeth, Haesebrouck, F., Vanhaecke, T., Rogiers, V., & Vinken, M. (2011). Modulation of connexin signaling by bacterial pathogens and their toxins. CELLULAR AND MOLECULAR LIFE SCIENCES, 68(18), 3047–3064.
Vancouver
1.
Ceelen L, Haesebrouck F, Vanhaecke T, Rogiers V, Vinken M. Modulation of connexin signaling by bacterial pathogens and their toxins. CELLULAR AND MOLECULAR LIFE SCIENCES. 2011;68(18):3047–64.
MLA
Ceelen, Liesbeth, Freddy Haesebrouck, Tamara Vanhaecke, et al. “Modulation of Connexin Signaling by Bacterial Pathogens and Their Toxins.” CELLULAR AND MOLECULAR LIFE SCIENCES 68.18 (2011): 3047–3064. Print.
@article{2064067,
  abstract     = {Inherent to their pivotal tasks in the maintenance of cellular homeostasis, gap junctions, connexin hemichannels, and pannexin hemichannels are frequently involved in the dysregulation of this critical balance. The present paper specifically focuses on their roles in bacterial infection and disease. In particular, the reported biological outcome of clinically important bacteria including Escherichia coli, Shigella flexneri, Yersinia enterocolitica, Helicobacter pylori, Bordetella pertussis, Aggregatibacter actinomycetemcomitans, Pseudomonas aeruginosa, Citrobacter rodentium, Clostridium species, Streptococcus pneumoniae, and Staphylococcus aureus and their toxic products on connexin- and pannexin-related signaling in host cells is reviewed. Particular attention is paid to the underlying molecular mechanisms of these effects as well as to the actual biological relevance of these findings.},
  author       = {Ceelen, Liesbeth and Haesebrouck, Freddy and Vanhaecke, Tamara and Rogiers, Vera and Vinken, Mathieu},
  issn         = {1420-682X},
  journal      = {CELLULAR AND MOLECULAR LIFE SCIENCES},
  keyword      = {Pannexin,Hemichannel,Connexin,Gap junction,Bacteria,Toxin,HELICOBACTER-PYLORI INFECTION,GAP-JUNCTION CHANNELS,TUMOR-NECROSIS-FACTOR,OF-THE-LITERATURE,MICROVASCULAR ENDOTHELIAL-CELLS,BORDETELLA-PERTUSSIS INFECTION,GASTRIC EPITHELIAL-CELLS,ESCHERICHIA-COLI,INTERCELLULAR COMMUNICATION,ACTINOBACILLUS-ACTINOMYCETEMCOMITANS},
  language     = {eng},
  number       = {18},
  pages        = {3047--3064},
  title        = {Modulation of connexin signaling by bacterial pathogens and their toxins},
  url          = {http://dx.doi.org/10.1007/s00018-011-0737-z},
  volume       = {68},
  year         = {2011},
}

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