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Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees

Dries Cardoen, Ulrich R Ernst, Matthias Van Vaerenbergh UGent, Bart Boerjan, Dirk de Graaf UGent, Tom Wenseleers, Liliane Schoofs and Peter Verleyen (2011) PLOS ONE. 6(6).
abstract
The eusocial societies of honeybees, where the queen is the only fertile female among tens of thousands sterile worker bees, have intrigued scientists for centuries. The proximate factors, which cause the inhibition of worker bee ovaries, remain largely unknown; as are the factors which cause the activation of worker ovaries upon the loss of queen and brood in the colony. In an attempt to reveal key players in the regulatory network, we made a proteomic comparison of hemolymph profiles of workers with completely activated ovaries vs. rudimentary ovaries. An unexpected finding of this study is the correlation between age matched worker sterility and the enrichment of Picorna-like virus proteins. Fertile workers, on the other hand, show the upregulation of potential components of the immune system. It remains to be investigated whether viral infections contribute to worker sterility directly or are the result of a weaker immune system of sterile workers.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
DEFORMED-WING-VIRUS, JUVENILE-HORMONE, BRAIN GENE-EXPRESSION, PICORNA-LIKE VIRUS, APIS-MELLIFERA L., GENOME-WIDE ANALYSIS, OVARY DEVELOPMENT, THIOREDOXIN PEROXIDASE, VARROA DESTRUCTOR, INSECT SOCIETIES
journal title
PLOS ONE
PLoS One
volume
6
issue
6
article_number
e20043
pages
7 pages
Web of Science type
Article
Web of Science id
000291730000007
JCR category
BIOLOGY
JCR impact factor
4.092 (2011)
JCR rank
12/84 (2011)
JCR quartile
1 (2011)
ISSN
1932-6203
DOI
10.1371/journal.pone.0020043
language
English
UGent publication?
yes
classification
A1
copyright statement
I have retained and own the full copyright for this publication
id
2059348
handle
http://hdl.handle.net/1854/LU-2059348
date created
2012-03-05 12:40:17
date last changed
2012-03-14 15:19:10
@article{2059348,
  abstract     = {The eusocial societies of honeybees, where the queen is the only fertile female among tens of thousands sterile worker bees, have intrigued scientists for centuries. The proximate factors, which cause the inhibition of worker bee ovaries, remain largely unknown; as are the factors which cause the activation of worker ovaries upon the loss of queen and brood in the colony. In an attempt to reveal key players in the regulatory network, we made a proteomic comparison of hemolymph profiles of workers with completely activated ovaries vs. rudimentary ovaries. An unexpected finding of this study is the correlation between age matched worker sterility and the enrichment of Picorna-like virus proteins. Fertile workers, on the other hand, show the upregulation of potential components of the immune system. It remains to be investigated whether viral infections contribute to worker sterility directly or are the result of a weaker immune system of sterile workers.},
  articleno    = {e20043},
  author       = {Cardoen, Dries and Ernst, Ulrich R and Van Vaerenbergh, Matthias and Boerjan, Bart and de Graaf, Dirk and Wenseleers, Tom and Schoofs, Liliane and Verleyen, Peter},
  issn         = {1932-6203},
  journal      = {PLOS ONE},
  keyword      = {DEFORMED-WING-VIRUS,JUVENILE-HORMONE,BRAIN GENE-EXPRESSION,PICORNA-LIKE VIRUS,APIS-MELLIFERA L.,GENOME-WIDE ANALYSIS,OVARY DEVELOPMENT,THIOREDOXIN PEROXIDASE,VARROA DESTRUCTOR,INSECT SOCIETIES},
  language     = {eng},
  number       = {6},
  pages        = {7},
  title        = {Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees},
  url          = {http://dx.doi.org/10.1371/journal.pone.0020043},
  volume       = {6},
  year         = {2011},
}

Chicago
Cardoen, Dries, Ulrich R Ernst, Matthias Van Vaerenbergh, Bart Boerjan, Dirk de Graaf, Tom Wenseleers, Liliane Schoofs, and Peter Verleyen. 2011. “Differential Proteomics in Dequeened Honeybee Colonies Reveals Lower Viral Load in Hemolymph of Fertile Worker Bees.” Plos One 6 (6).
APA
Cardoen, D., Ernst, U. R., Van Vaerenbergh, M., Boerjan, B., de Graaf, D., Wenseleers, T., Schoofs, L., et al. (2011). Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees. PLOS ONE, 6(6).
Vancouver
1.
Cardoen D, Ernst UR, Van Vaerenbergh M, Boerjan B, de Graaf D, Wenseleers T, et al. Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees. PLOS ONE. 2011;6(6).
MLA
Cardoen, Dries, Ulrich R Ernst, Matthias Van Vaerenbergh, et al. “Differential Proteomics in Dequeened Honeybee Colonies Reveals Lower Viral Load in Hemolymph of Fertile Worker Bees.” PLOS ONE 6.6 (2011): n. pag. Print.