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Molecular cytogenetic analysis of XX males using Y-specific DNA-sequences, including SRY

B Van der Auwera, Nadine Van Roy UGent, Anne De Paepe UGent, JR Hawkins, I Liebaers, S Castedo, J Dumon and Franki Speleman UGent (1992) HUMAN GENETICS. 89(1). p.23-28
abstract
XX maleness is the most common condition in which testes develop in the absence of a cytogenetically detectable Y chromosome. Using molecular techniques, it is possible to detect Yp sequences in the majority of XX males. In this study, we could detect Y-specific sequences, including the sex-determining region of the Y chromosome (SRY), using fluorescence in situ hybridization. In 5 out of 6 previously unpublished XX males, SRY was translocated onto the terminal part of an X chromosome. This is the first report in which translocation of an SRY-bearing fragment to an X chromosome in XX males could be directly demonstrated.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
SHORT ARM, SEX-DETERMINING REGION, INSITU HYBRIDIZATION, CHROMOSOME SEQUENCES, TRUE HERMAPHRODITES, REPEAT FAMILY, XY FEMALE, LOCALIZATION, INTERCHANGE, 46, XX
journal title
HUMAN GENETICS
Hum. Genet.
volume
89
issue
1
pages
23 - 28
Web of Science type
Article
ISSN
0340-6717
DOI
10.1007/BF00207036
language
English
UGent publication?
yes
classification
A1
additional info
gtdt ; dubbel was: http://hdl.handle.net/1854/LU-234940
id
205469
handle
http://hdl.handle.net/1854/LU-205469
date created
2004-01-14 13:42:00
date last changed
2016-12-19 15:38:27
@article{205469,
  abstract     = {XX maleness is the most common condition in which testes develop in the absence of a cytogenetically detectable Y chromosome. Using molecular techniques, it is possible to detect Yp sequences in the majority of XX males. In this study, we could detect Y-specific sequences, including the sex-determining region of the Y chromosome (SRY), using fluorescence in situ hybridization. In 5 out of 6 previously unpublished XX males, SRY was translocated onto the terminal part of an X chromosome. This is the first report in which translocation of an SRY-bearing fragment to an X chromosome in XX males could be directly demonstrated.},
  author       = {Van der Auwera, B and Van Roy, Nadine and De Paepe, Anne and Hawkins, JR and Liebaers, I and Castedo, S and Dumon, J and Speleman, Franki},
  issn         = {0340-6717},
  journal      = {HUMAN GENETICS},
  keyword      = {SHORT ARM,SEX-DETERMINING REGION,INSITU HYBRIDIZATION,CHROMOSOME SEQUENCES,TRUE HERMAPHRODITES,REPEAT FAMILY,XY FEMALE,LOCALIZATION,INTERCHANGE,46,XX},
  language     = {eng},
  number       = {1},
  pages        = {23--28},
  title        = {Molecular cytogenetic analysis of XX males using Y-specific DNA-sequences, including SRY},
  url          = {http://dx.doi.org/10.1007/BF00207036},
  volume       = {89},
  year         = {1992},
}

Chicago
Van der Auwera, B, Nadine Van Roy, Anne De Paepe, JR Hawkins, I Liebaers, S Castedo, J Dumon, and Franki Speleman. 1992. “Molecular Cytogenetic Analysis of XX Males Using Y-specific DNA-sequences, Including SRY.” Human Genetics 89 (1): 23–28.
APA
Van der Auwera, B., Van Roy, N., De Paepe, A., Hawkins, J., Liebaers, I., Castedo, S., Dumon, J., et al. (1992). Molecular cytogenetic analysis of XX males using Y-specific DNA-sequences, including SRY. HUMAN GENETICS, 89(1), 23–28.
Vancouver
1.
Van der Auwera B, Van Roy N, De Paepe A, Hawkins J, Liebaers I, Castedo S, et al. Molecular cytogenetic analysis of XX males using Y-specific DNA-sequences, including SRY. HUMAN GENETICS. 1992;89(1):23–8.
MLA
Van der Auwera, B, Nadine Van Roy, Anne De Paepe, et al. “Molecular Cytogenetic Analysis of XX Males Using Y-specific DNA-sequences, Including SRY.” HUMAN GENETICS 89.1 (1992): 23–28. Print.