Ghent University Academic Bibliography

Advanced

TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation

Paras K Anand, Stephen WG Tait, Mohamed Lamkanfi UGent, Amal O Amer, Gabriel Nunez, Gilles Pagès, Jacques Pouysségur, Maureen A McGargill, Douglas R Green and Thirumala-Devi Kanneganti (2011) JOURNAL OF BIOLOGICAL CHEMISTRY. 286(50). p.42981-42991
abstract
Background: Listeria monocytogenes is an intracellular pathogen that invades the host cytoplasm. Results: Cells deficient in TLR2 and NOD2 show defective autophagy of Listeria monocytogenes. Conclusion: Autophagy of Listeria is dependent on ERK pathway that is perturbed in TLR2- and NOD2-deficient cells. Significance: Our study establishes the role of innate immune receptors in autophagy of intracellular pathogens.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
ADAPTIVE IMMUNITY, CRYOPYRIN INFLAMMASOME, EPITHELIAL-CELLS, CROHN-DISEASE, HOST-DEFENSE, EARLY PHASE, INFECTION, INTRACELLULAR PATHOGENS, INNATE IMMUNITY, GENOME-WIDE ASSOCIATION
journal title
JOURNAL OF BIOLOGICAL CHEMISTRY
J. Biol. Chem.
volume
286
issue
50
pages
42981 - 42991
Web of Science type
Article
Web of Science id
000298351300019
JCR category
BIOCHEMISTRY & MOLECULAR BIOLOGY
JCR impact factor
4.773 (2011)
JCR rank
66/286 (2011)
JCR quartile
1 (2011)
ISSN
0021-9258
DOI
10.1074/jbc.M111.310599
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
2054453
handle
http://hdl.handle.net/1854/LU-2054453
date created
2012-03-01 10:31:06
date last changed
2012-03-08 10:07:07
@article{2054453,
  abstract     = {Background: Listeria monocytogenes is an intracellular pathogen that invades the host cytoplasm.
Results: Cells deficient in TLR2 and NOD2 show defective autophagy of Listeria monocytogenes.
Conclusion: Autophagy of Listeria is dependent on ERK pathway that is perturbed in TLR2- and NOD2-deficient cells.
Significance: Our study establishes the role of innate immune receptors in autophagy of intracellular pathogens.},
  author       = {Anand, Paras K and Tait, Stephen WG and Lamkanfi, Mohamed and Amer, Amal O and Nunez, Gabriel and Pag{\`e}s, Gilles and Pouyss{\'e}gur, Jacques and McGargill, Maureen A and Green, Douglas R and Kanneganti, Thirumala-Devi},
  issn         = {0021-9258},
  journal      = {JOURNAL OF BIOLOGICAL CHEMISTRY},
  keyword      = {ADAPTIVE IMMUNITY,CRYOPYRIN INFLAMMASOME,EPITHELIAL-CELLS,CROHN-DISEASE,HOST-DEFENSE,EARLY PHASE,INFECTION,INTRACELLULAR PATHOGENS,INNATE IMMUNITY,GENOME-WIDE ASSOCIATION},
  language     = {eng},
  number       = {50},
  pages        = {42981--42991},
  title        = {TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation},
  url          = {http://dx.doi.org/10.1074/jbc.M111.310599},
  volume       = {286},
  year         = {2011},
}

Chicago
Anand, Paras K, Stephen WG Tait, Mohamed Lamkanfi, Amal O Amer, Gabriel Nunez, Gilles Pagès, Jacques Pouysségur, Maureen A McGargill, Douglas R Green, and Thirumala-Devi Kanneganti. 2011. “TLR2 and RIP2 Pathways Mediate Autophagy of Listeria Monocytogenes via Extracellular Signal-regulated Kinase (ERK) Activation.” Journal of Biological Chemistry 286 (50): 42981–42991.
APA
Anand, P. K., Tait, S. W., Lamkanfi, M., Amer, A. O., Nunez, G., Pagès, G., Pouysségur, J., et al. (2011). TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation. JOURNAL OF BIOLOGICAL CHEMISTRY, 286(50), 42981–42991.
Vancouver
1.
Anand PK, Tait SW, Lamkanfi M, Amer AO, Nunez G, Pagès G, et al. TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation. JOURNAL OF BIOLOGICAL CHEMISTRY. 2011;286(50):42981–91.
MLA
Anand, Paras K, Stephen WG Tait, Mohamed Lamkanfi, et al. “TLR2 and RIP2 Pathways Mediate Autophagy of Listeria Monocytogenes via Extracellular Signal-regulated Kinase (ERK) Activation.” JOURNAL OF BIOLOGICAL CHEMISTRY 286.50 (2011): 42981–42991. Print.