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The importance of sample size in the determination of a flock-level antimicrobial resistance profile for Escherichia coli in broilers

(2011) MICROBIAL DRUG RESISTANCE. 17(4). p.513-519
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Abstract
Determining herd- or flock-specific antimicrobial resistance profiles is important to guide therapeutic use of antimicrobials and to assess risk factors for the development and spread of antimicrobial resistance. As such, it is of utmost importance to optimize the sampling strategy for the determination of herd-specific antimicrobial resistance profiles. However, the multitude of prevalences measured at the same time as well as the presence of variation both at the level of the animal and the bacterial population of concern make it impossible to use conventional sample size determination methods. In this article, the use of bootstrapping techniques for sample size determination was explored. In particular, one-stage and two-stage bootstrap samplings were used to determine the optimal number of animals and the optimal number of isolates within one animal. Results show that focus should be on the number of animals sampled rather than on the number of isolates tested within one animal.
Keywords
VARIABILITY, IMPACT, CHICKENS, SUSCEPTIBILITY, FOOD, VARIANCE COMPONENT ESTIMATION, BACTERIA, PREVALENCE, ANIMALS, STRAINS

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Citation

Please use this url to cite or link to this publication:

Chicago
Persoons, Davy, Kaatje Bollaerts, Annemieke Smet, Lieve Herman, Marc Heyndrickx, An Martel, Patrick Butaye, Boudewijn Catry, Freddy Haesebrouck, and Jeroen Dewulf. 2011. “The Importance of Sample Size in the Determination of a Flock-level Antimicrobial Resistance Profile for Escherichia Coli in Broilers.” Microbial Drug Resistance 17 (4): 513–519.
APA
Persoons, D., Bollaerts, K., Smet, A., Herman, L., Heyndrickx, M., Martel, A., Butaye, P., et al. (2011). The importance of sample size in the determination of a flock-level antimicrobial resistance profile for Escherichia coli in broilers. MICROBIAL DRUG RESISTANCE, 17(4), 513–519.
Vancouver
1.
Persoons D, Bollaerts K, Smet A, Herman L, Heyndrickx M, Martel A, et al. The importance of sample size in the determination of a flock-level antimicrobial resistance profile for Escherichia coli in broilers. MICROBIAL DRUG RESISTANCE. 2011;17(4):513–9.
MLA
Persoons, Davy, Kaatje Bollaerts, Annemieke Smet, et al. “The Importance of Sample Size in the Determination of a Flock-level Antimicrobial Resistance Profile for Escherichia Coli in Broilers.” MICROBIAL DRUG RESISTANCE 17.4 (2011): 513–519. Print.
@article{2053613,
  abstract     = {Determining herd- or flock-specific antimicrobial resistance profiles is important to guide therapeutic use of antimicrobials and to assess risk factors for the development and spread of antimicrobial resistance. As such, it is of utmost importance to optimize the sampling strategy for the determination of herd-specific antimicrobial resistance profiles. However, the multitude of prevalences measured at the same time as well as the presence of variation both at the level of the animal and the bacterial population of concern make it impossible to use conventional sample size determination methods. In this article, the use of bootstrapping techniques for sample size determination was explored. In particular, one-stage and two-stage bootstrap samplings were used to determine the optimal number of animals and the optimal number of isolates within one animal. Results show that focus should be on the number of animals sampled rather than on the number of isolates tested within one animal.},
  author       = {Persoons, Davy and Bollaerts, Kaatje and Smet, Annemieke and Herman, Lieve and Heyndrickx, Marc and Martel, An and Butaye, Patrick and Catry, Boudewijn and Haesebrouck, Freddy and Dewulf, Jeroen},
  issn         = {1076-6294},
  journal      = {MICROBIAL DRUG RESISTANCE},
  keyword      = {VARIABILITY,IMPACT,CHICKENS,SUSCEPTIBILITY,FOOD,VARIANCE COMPONENT ESTIMATION,BACTERIA,PREVALENCE,ANIMALS,STRAINS},
  language     = {eng},
  number       = {4},
  pages        = {513--519},
  title        = {The importance of sample size in the determination of a flock-level antimicrobial resistance profile for Escherichia coli in broilers},
  url          = {http://dx.doi.org/10.1089/mdr.2011.0048},
  volume       = {17},
  year         = {2011},
}

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