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Diversity-oriented synthesis of substituted furo[2,3-b]pyrazines

Vaibhav Pravinchandra Mehta, Sachin G Modha, Denis Ermolat'ev, Kristof Van Hecke UGent, Luc Van Meervelt and Erik V Van der Eycken (2009) AUSTRALIAN JOURNAL OF CHEMISTRY. 62(1). p.27-41
abstract
A highly efficient method for the synthesis of diversely substituted furo[2,3-b] pyrazines has been elaborated. The Ag(+)- or iodine-mediated electrophilic cyclization of readily generated 5-chloro-3-substituted ethynyl-1-(4-methoxybenzyl)pyrazin-2(1H)-ones affords substituted furo[2,3-b] pyrazines, which undergo various palladium catalyzed reactions to generate a library of difficult to attain diversely substituted furo[2,3-b] pyrazines.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
ELECTROPHILIC CYCLIZATION, PALLADIUM-CATALYZED ANNULATION, AROMATIC HETEROCYCLES, 2-SUBSTITUTED DERIVATIVES, 5-ENDO-DIG CYCLIZATIONS, COUPLING REACTIONS, CRYSTAL-STRUCTURE, TERMINAL ALKYNES, O-ALKYNYLPHENOLS, BETA-IODOFURANS
journal title
AUSTRALIAN JOURNAL OF CHEMISTRY
Aust. J. Chem.
volume
62
issue
1
pages
27 - 41
Web of Science type
Article
Web of Science id
000262656200004
JCR category
CHEMISTRY, MULTIDISCIPLINARY
JCR impact factor
1.959 (2009)
JCR rank
44/137 (2009)
JCR quartile
2 (2009)
ISSN
0004-9425
DOI
10.1071/CH08376
language
English
UGent publication?
no
classification
A1
id
2045663
handle
http://hdl.handle.net/1854/LU-2045663
date created
2012-02-27 11:02:18
date last changed
2018-01-29 12:12:31
@article{2045663,
  abstract     = {A highly efficient method for the synthesis of diversely substituted furo[2,3-b] pyrazines has been elaborated. The Ag(+)- or iodine-mediated electrophilic cyclization of readily generated 5-chloro-3-substituted ethynyl-1-(4-methoxybenzyl)pyrazin-2(1H)-ones affords substituted furo[2,3-b] pyrazines, which undergo various palladium catalyzed reactions to generate a library of difficult to attain diversely substituted furo[2,3-b] pyrazines.},
  author       = {Mehta, Vaibhav Pravinchandra and Modha, Sachin G and Ermolat'ev, Denis and Van Hecke, Kristof and Van Meervelt, Luc and Van der Eycken, Erik V},
  issn         = {0004-9425},
  journal      = {AUSTRALIAN JOURNAL OF CHEMISTRY},
  keyword      = {ELECTROPHILIC CYCLIZATION,PALLADIUM-CATALYZED ANNULATION,AROMATIC HETEROCYCLES,2-SUBSTITUTED DERIVATIVES,5-ENDO-DIG CYCLIZATIONS,COUPLING REACTIONS,CRYSTAL-STRUCTURE,TERMINAL ALKYNES,O-ALKYNYLPHENOLS,BETA-IODOFURANS},
  language     = {eng},
  number       = {1},
  pages        = {27--41},
  title        = {Diversity-oriented synthesis of substituted furo[2,3-b]pyrazines},
  url          = {http://dx.doi.org/10.1071/CH08376},
  volume       = {62},
  year         = {2009},
}

Chicago
Mehta, Vaibhav Pravinchandra, Sachin G Modha, Denis Ermolat’ev, Kristof Van Hecke, Luc Van Meervelt, and Erik V Van der Eycken. 2009. “Diversity-oriented Synthesis of Substituted Furo[2,3-b]pyrazines.” Australian Journal of Chemistry 62 (1): 27–41.
APA
Mehta, V. P., Modha, S. G., Ermolat’ev, D., Van Hecke, K., Van Meervelt, L., & Van der Eycken, E. V. (2009). Diversity-oriented synthesis of substituted furo[2,3-b]pyrazines. AUSTRALIAN JOURNAL OF CHEMISTRY, 62(1), 27–41.
Vancouver
1.
Mehta VP, Modha SG, Ermolat’ev D, Van Hecke K, Van Meervelt L, Van der Eycken EV. Diversity-oriented synthesis of substituted furo[2,3-b]pyrazines. AUSTRALIAN JOURNAL OF CHEMISTRY. 2009;62(1):27–41.
MLA
Mehta, Vaibhav Pravinchandra, Sachin G Modha, Denis Ermolat’ev, et al. “Diversity-oriented Synthesis of Substituted Furo[2,3-b]pyrazines.” AUSTRALIAN JOURNAL OF CHEMISTRY 62.1 (2009): 27–41. Print.