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Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity

Lies De Bock, Koen Boussery (UGent) , Pieter Colin (UGent) , Julie De Smet (UGent) , Huybrecht T'jollyn (UGent) and Jan Van Bocxlaer (UGent)
(2012) TALANTA. 89. p.209-216
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Ultra high performance liquid chromatography-mass spectrometry, Cytochrome P450, Validation, TANDEM MASS-SPECTROMETRY, LIQUID-CHROMATOGRAPHY, INHIBITION ASSAYS, LC-MS/MS, ENZYMES, STRATEGIES, LIVER, COCKTAIL, P450S, Drug metabolism, Human liver microsomes

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Chicago
De Bock, Lies, Koen Boussery, Pieter Colin, Julie De Smet, Huybrecht T’jollyn, and Jan Van Bocxlaer. 2012. “Development and Validation of a Fast and Sensitive UPLC-MS/MS Method for the Quantification of Six Probe Metabolites for the in Vitro Determination of Cytochrome P450 Activity.” Talanta 89: 209–216.
APA
De Bock, Lies, Boussery, K., Colin, P., De Smet, J., T’jollyn, H., & Van Bocxlaer, J. (2012). Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity. TALANTA, 89, 209–216.
Vancouver
1.
De Bock L, Boussery K, Colin P, De Smet J, T’jollyn H, Van Bocxlaer J. Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity. TALANTA. 2012;89:209–16.
MLA
De Bock, Lies, Koen Boussery, Pieter Colin, et al. “Development and Validation of a Fast and Sensitive UPLC-MS/MS Method for the Quantification of Six Probe Metabolites for the in Vitro Determination of Cytochrome P450 Activity.” TALANTA 89 (2012): 209–216. Print.
@article{2044821,
  author       = {De Bock, Lies and Boussery, Koen and Colin, Pieter and De Smet, Julie and T'jollyn, Huybrecht and Van Bocxlaer, Jan},
  issn         = {0039-9140},
  journal      = {TALANTA},
  keyword      = {Ultra high performance liquid chromatography-mass spectrometry,Cytochrome P450,Validation,TANDEM MASS-SPECTROMETRY,LIQUID-CHROMATOGRAPHY,INHIBITION ASSAYS,LC-MS/MS,ENZYMES,STRATEGIES,LIVER,COCKTAIL,P450S,Drug metabolism,Human liver microsomes},
  language     = {eng},
  pages        = {209--216},
  title        = {Development and validation of a fast and sensitive UPLC-MS/MS method for the quantification of six probe metabolites for the in vitro determination of cytochrome P450 activity},
  url          = {http://dx.doi.org/10.1016/j.talanta.2011.11.083},
  volume       = {89},
  year         = {2012},
}

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