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Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so-gradual process

Megan Andriankaja (UGent) , Stijn Dhondt (UGent) , Stefanie De Bodt (UGent) , Hannes Vanhaeren (UGent) , Frederik Coppens (UGent) , Liesbeth De Milde (UGent) , Per Mühlenbock (UGent) , Aleksandra Skirycz (UGent) , Nathalie Gonzalez Sanchez (UGent) , Gerrit Beemster (UGent) , et al.
(2012) DEVELOPMENTAL CELL. 22(1). p.64-78
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Biotechnology for a sustainable economy (Bio-Economy)
Abstract
Early leaf growth is sustained by cell proliferation and subsequent cell expansion that initiates at the leaf tip and proceeds in a basipetal direction. Using detailed kinematic and gene expression studies to map these stages during early development of the third leaf of Arabidopsis thaliana, we showed that the cell-cycle arrest front did not progress gradually down the leaf, but rather was established and abolished abruptly. Interestingly, leaf greening and stomatal patterning followed a similar basipetal pattern, but proliferative pavement cell and formative meristemoid divisions were uncoordinated in respect to onset and persistence. Genes differentially expressed during the transition from cell proliferation to expansion were enriched in genes involved in cell cycle, photosynthesis, and chloroplast retrograde signaling. Proliferating primordia treated with norflurazon, a chemical inhibitor of retrograde signaling, showed inhibited onset of cell expansion. Hence, differentiation of the photosynthetic machinery is important for regulating the exit from proliferation.
Keywords
PLANT ORGAN SIZE, GENOME-WIDE ANALYSIS, NUCLEAR-DNA REPLICATION, CELL-CYCLE, GENE-EXPRESSION, STOMATAL DEVELOPMENT, DEVELOPING LEAVES, SHOOT APEX, GROWTH, MORPHOGENESIS

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Citation

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Chicago
Andriankaja, Megan, Stijn Dhondt, Stefanie De Bodt, Hannes Vanhaeren, Frederik Coppens, Liesbeth De Milde, Per Mühlenbock, et al. 2012. “Exit from Proliferation During Leaf Development in Arabidopsis Thaliana: a Not-so-gradual Process.” Developmental Cell 22 (1): 64–78.
APA
Andriankaja, M., Dhondt, S., De Bodt, S., Vanhaeren, H., Coppens, F., De Milde, L., Mühlenbock, P., et al. (2012). Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so-gradual process. DEVELOPMENTAL CELL, 22(1), 64–78.
Vancouver
1.
Andriankaja M, Dhondt S, De Bodt S, Vanhaeren H, Coppens F, De Milde L, et al. Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so-gradual process. DEVELOPMENTAL CELL. 2012;22(1):64–78.
MLA
Andriankaja, Megan, Stijn Dhondt, Stefanie De Bodt, et al. “Exit from Proliferation During Leaf Development in Arabidopsis Thaliana: a Not-so-gradual Process.” DEVELOPMENTAL CELL 22.1 (2012): 64–78. Print.
@article{2042304,
  abstract     = {Early leaf growth is sustained by cell proliferation and subsequent cell expansion that initiates at the leaf tip and proceeds in a basipetal direction. Using detailed kinematic and gene expression studies to map these stages during early development of the third leaf of Arabidopsis thaliana, we showed that the cell-cycle arrest front did not progress gradually down the leaf, but rather was established and abolished abruptly. Interestingly, leaf greening and stomatal patterning followed a similar basipetal pattern, but proliferative pavement cell and formative meristemoid divisions were uncoordinated in respect to onset and persistence. Genes differentially expressed during the transition from cell proliferation to expansion were enriched in genes involved in cell cycle, photosynthesis, and chloroplast retrograde signaling. Proliferating primordia treated with norflurazon, a chemical inhibitor of retrograde signaling, showed inhibited onset of cell expansion. Hence, differentiation of the photosynthetic machinery is important for regulating the exit from proliferation.},
  author       = {Andriankaja, Megan and Dhondt, Stijn and De Bodt, Stefanie and Vanhaeren, Hannes and Coppens, Frederik and De Milde, Liesbeth and M{\"u}hlenbock, Per and Skirycz, Aleksandra and Gonzalez Sanchez, Nathalie and Beemster, Gerrit and Inz{\'e}, Dirk},
  issn         = {1534-5807},
  journal      = {DEVELOPMENTAL CELL},
  keyword      = {PLANT ORGAN SIZE,GENOME-WIDE ANALYSIS,NUCLEAR-DNA REPLICATION,CELL-CYCLE,GENE-EXPRESSION,STOMATAL DEVELOPMENT,DEVELOPING LEAVES,SHOOT APEX,GROWTH,MORPHOGENESIS},
  language     = {eng},
  number       = {1},
  pages        = {64--78},
  title        = {Exit from proliferation during leaf development in Arabidopsis thaliana: a not-so-gradual process},
  url          = {http://dx.doi.org/10.1016/j.devcel.2011.11.011},
  volume       = {22},
  year         = {2012},
}

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