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Effect of radiation dose on the prevalence of apical periodontitis: a dosimetric analysis

Geert Hommez UGent, Gert De Meerleer UGent, Wilfried De Neve UGent and Roeland De Moor UGent (2012) CLINICAL ORAL INVESTIGATIONS. 16(6). p.1543-1547
abstract
Objectives : The objective of this study is to analyse the effect of the radiation dose of oral radiotherapy for cancer on the presence of apical periodontitis in patients without dental pre-screening or specific preventive measures. Materials and methods : All selected patients had been diagnosed with cancer in the head and neck region and presented in the dental clinic post radiotherapy with side effects (mainly radiation caries). The panoramic radiographs of these patients were examined for several parameters, including tooth decay and apical periodontitis. The total radiation dose per tooth was determined. Results : A total of 36 patient files were included, which accounted for 628 teeth to be scored. Tooth decay was present in 88.2% of teeth. Radiographic signs of apical periodontitis were found in 9.1% of the teeth. Teeth with apical periodontitis had significantly more caries present. The radiation dose was significantly higher for teeth with apical periodontitis (37.2 vs. 24.9 Gy). Binary logistic regression found the radiation dose to be the only explanatory variable in the presence of apical periodontitis. Conclusions : This study found that in zones with higher radiation dose, inflammation of the jawbone due to bacterial infection of the root canal is more likely to develop. This is probably due to bone changes post radiotherapy. Clinical relevance : An increase of this prevalance of apical periodontitis in irradiated bone found in this study needs to be taken into account in the dental evaluation before the start of radiotherapy.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
Radiotherapy, Head and neck cancer, Apical periodontitis, Root canal, Side effects, Bone inflammation, ROOT-FILLED TEETH, PANORAMIC RADIOGRAPHY, PERIAPICAL STATUS, POPULATION, RADIOTHERAPY, MICROFLORA, HEAD, MICROORGANISMS, IRRADIATION, XEROSTOMIA
journal title
CLINICAL ORAL INVESTIGATIONS
Clin. Oral Investig.
volume
16
issue
6
pages
1543 - 1547
Web of Science type
Article
Web of Science id
000311362300005
JCR category
DENTISTRY, ORAL SURGERY & MEDICINE
JCR impact factor
2.2 (2012)
JCR rank
19/81 (2012)
JCR quartile
1 (2012)
ISSN
1432-6981
DOI
10.1007/s00784-011-0665-1
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
2028844
handle
http://hdl.handle.net/1854/LU-2028844
date created
2012-02-13 17:35:47
date last changed
2013-07-09 13:52:44
@article{2028844,
  abstract     = {Objectives : The objective of this study is to analyse the effect of the radiation dose of oral radiotherapy for cancer on the presence of apical periodontitis in patients without dental pre-screening or specific preventive measures. 
Materials and methods : All selected patients had been diagnosed with cancer in the head and neck region and presented in the dental clinic post radiotherapy with side effects (mainly radiation caries). The panoramic radiographs of these patients were examined for several parameters, including tooth decay and apical periodontitis. The total radiation dose per tooth was determined. 
Results : A total of 36 patient files were included, which accounted for 628 teeth to be scored. Tooth decay was present in 88.2\% of teeth. Radiographic signs of apical periodontitis were found in 9.1\% of the teeth. Teeth with apical periodontitis had significantly more caries present. The radiation dose was significantly higher for teeth with apical periodontitis (37.2 vs. 24.9 Gy). Binary logistic regression found the radiation dose to be the only explanatory variable in the presence of apical periodontitis. 
Conclusions : This study found that in zones with higher radiation dose, inflammation of the jawbone due to bacterial infection of the root canal is more likely to develop. This is probably due to bone changes post radiotherapy. 
Clinical relevance : An increase of this prevalance of apical periodontitis in irradiated bone found in this study needs to be taken into account in the dental evaluation before the start of radiotherapy.},
  author       = {Hommez, Geert and De Meerleer, Gert and De Neve, Wilfried and De Moor, Roeland},
  issn         = {1432-6981},
  journal      = {CLINICAL ORAL INVESTIGATIONS},
  keyword      = {Radiotherapy,Head and neck cancer,Apical periodontitis,Root canal,Side effects,Bone inflammation,ROOT-FILLED TEETH,PANORAMIC RADIOGRAPHY,PERIAPICAL STATUS,POPULATION,RADIOTHERAPY,MICROFLORA,HEAD,MICROORGANISMS,IRRADIATION,XEROSTOMIA},
  language     = {eng},
  number       = {6},
  pages        = {1543--1547},
  title        = {Effect of radiation dose on the prevalence of apical periodontitis: a dosimetric analysis},
  url          = {http://dx.doi.org/10.1007/s00784-011-0665-1},
  volume       = {16},
  year         = {2012},
}

Chicago
Hommez, Geert, Gert De Meerleer, Wilfried De Neve, and Roeland De Moor. 2012. “Effect of Radiation Dose on the Prevalence of Apical Periodontitis: a Dosimetric Analysis.” Clinical Oral Investigations 16 (6): 1543–1547.
APA
Hommez, G., De Meerleer, G., De Neve, W., & De Moor, R. (2012). Effect of radiation dose on the prevalence of apical periodontitis: a dosimetric analysis. CLINICAL ORAL INVESTIGATIONS, 16(6), 1543–1547.
Vancouver
1.
Hommez G, De Meerleer G, De Neve W, De Moor R. Effect of radiation dose on the prevalence of apical periodontitis: a dosimetric analysis. CLINICAL ORAL INVESTIGATIONS. 2012;16(6):1543–7.
MLA
Hommez, Geert, Gert De Meerleer, Wilfried De Neve, et al. “Effect of Radiation Dose on the Prevalence of Apical Periodontitis: a Dosimetric Analysis.” CLINICAL ORAL INVESTIGATIONS 16.6 (2012): 1543–1547. Print.