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Lung dendritic cell-epithelial cell crosstalk in Th2 responses to allergens

Monique Willart and Hamida Hammad UGent (2011) CURRENT OPINION IN IMMUNOLOGY. 23(6). p.772-777
abstract
Dendritic cells (DC) have been shown to be responsible for the initiation and maintenance of adaptive Th2 responses in asthma. It is increasingly clear that DC functions are strongly influenced by crosstalk with neighboring cells like epithelial cells, which can release a number of innate cytokines promoting Th2 responses. Clinically relevant allergens often interfere directly or indirectly with the innate immune functions of airway epithelial cells and DC. A better understanding of these interactions might lead to a better prevention and ultimately to new treatments for asthma.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (review)
publication status
published
subject
keyword
IMMUNE-RESPONSES, AIRWAY INFLAMMATION, INHALED ANTIGEN, GM-CSF, INTERLEUKIN-1 FAMILY, DEPENDENT PATHWAYS, GERMAN-COCKROACH FRASS, NF-KAPPA-B, HOUSE-DUST MITE, THYMIC STROMAL LYMPHOPOIETIN
journal title
CURRENT OPINION IN IMMUNOLOGY
Curr. Opin. Immunol.
volume
23
issue
6
pages
772 - 777
Web of Science type
Review
Web of Science id
000298623100012
JCR category
IMMUNOLOGY
JCR impact factor
9.522 (2011)
JCR rank
9/138 (2011)
JCR quartile
1 (2011)
ISSN
0952-7915
DOI
10.1016/j.coi.2011.09.008
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
2022727
handle
http://hdl.handle.net/1854/LU-2022727
date created
2012-02-07 16:47:25
date last changed
2016-12-19 15:39:43
@article{2022727,
  abstract     = {Dendritic cells (DC) have been shown to be responsible for the initiation and maintenance of adaptive Th2 responses in asthma. It is increasingly clear that DC functions are strongly influenced by crosstalk with neighboring cells like epithelial cells, which can release a number of innate cytokines promoting Th2 responses. Clinically relevant allergens often interfere directly or indirectly with the innate immune functions of airway epithelial cells and DC. A better understanding of these interactions might lead to a better prevention and ultimately to new treatments for asthma.},
  author       = {Willart, Monique and Hammad, Hamida},
  issn         = {0952-7915},
  journal      = {CURRENT OPINION IN IMMUNOLOGY},
  keyword      = {IMMUNE-RESPONSES,AIRWAY INFLAMMATION,INHALED ANTIGEN,GM-CSF,INTERLEUKIN-1 FAMILY,DEPENDENT PATHWAYS,GERMAN-COCKROACH FRASS,NF-KAPPA-B,HOUSE-DUST MITE,THYMIC STROMAL LYMPHOPOIETIN},
  language     = {eng},
  number       = {6},
  pages        = {772--777},
  title        = {Lung dendritic cell-epithelial cell crosstalk in Th2 responses to allergens},
  url          = {http://dx.doi.org/10.1016/j.coi.2011.09.008},
  volume       = {23},
  year         = {2011},
}

Chicago
Willart, Monique, and Hamida Hammad. 2011. “Lung Dendritic Cell-epithelial Cell Crosstalk in Th2 Responses to Allergens.” Current Opinion in Immunology 23 (6): 772–777.
APA
Willart, M., & Hammad, H. (2011). Lung dendritic cell-epithelial cell crosstalk in Th2 responses to allergens. CURRENT OPINION IN IMMUNOLOGY, 23(6), 772–777.
Vancouver
1.
Willart M, Hammad H. Lung dendritic cell-epithelial cell crosstalk in Th2 responses to allergens. CURRENT OPINION IN IMMUNOLOGY. 2011;23(6):772–7.
MLA
Willart, Monique, and Hamida Hammad. “Lung Dendritic Cell-epithelial Cell Crosstalk in Th2 Responses to Allergens.” CURRENT OPINION IN IMMUNOLOGY 23.6 (2011): 772–777. Print.