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Reproducibility of 3D 1H MR spectroscopic imaging of the prostate at 1.5T

Miriam W Lagemaat, Christian M Zechmann, Jurgen J Futterer, Elisabeth Weiland, Jianping Lu, Geert Villeirs UGent, Barbara A Holshouser, Paul van Hecke, Marc Lemort and Heinz-Peter Schlemmer, et al. (2012) JOURNAL OF MAGNETIC RESONANCE IMAGING. 35(1). p.166-173
abstract
Purpose: To determine the reproducibility of 3D proton magnetic resonance spectroscopic imaging (1H-MRSI) of the human prostate in a multicenter setting at 1.5T. Materials and Methods: Fourteen subjects were measured twice with 3D point-resolved spectroscopy (PRESS) (1)H-MRSI using an endorectal coil. MRSI voxels were selected in the peripheral zone and combined central gland at the same location in the prostate in both measurements. Voxels with approved spectral quality were included to calculate Bland-Altman parameters for reproducibility from the choline plus creatine to citrate ratio (CC/C). The repeated spectroscopic data were also evaluated with a standardized clinical scoring system. Results: A total of 74 voxels were included for reproducibility analysis. The complete range of biologically interesting CC/C ratios was covered. The overall within-voxel standard deviation (SD) of the CC/C ratio of the repeated measurements was 0.13. This value is equal to the between-subject SD of noncancer prostate tissue. In >90% of the voxels the standardized clinical score did not differ relevantly between the measurements. Conclusion: Repeated measurements of in vivo 3D (1)H-MRSI of the complete prostate at 1.5T produce equal and quantitative results. The reproducibility of the technique is high enough to provide it as a reliable tool in assessing tumor presence in the prostate.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
3T, TISSUE, SEXTANT LOCALIZATION, CANCER LOCALIZATION, reproducibility, MAGNETIC-RESONANCE-SPECTROSCOPY, HUMAN BRAIN, prostate cancer, magnetic resonance spectroscopic imaging
journal title
JOURNAL OF MAGNETIC RESONANCE IMAGING
J. Magn. Reson. Imaging
volume
35
issue
1
pages
166 - 173
Web of Science type
Article
Web of Science id
000298093200019
JCR category
RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
JCR impact factor
2.566 (2012)
JCR rank
38/119 (2012)
JCR quartile
2 (2012)
ISSN
1053-1807
DOI
10.1002/jmri.22827
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
2018524
handle
http://hdl.handle.net/1854/LU-2018524
date created
2012-02-03 13:30:55
date last changed
2012-03-20 15:34:27
@article{2018524,
  abstract     = {Purpose: To determine the reproducibility of 3D proton magnetic resonance spectroscopic imaging (1H-MRSI) of the human prostate in a multicenter setting at 1.5T. 
Materials and Methods: Fourteen subjects were measured twice with 3D point-resolved spectroscopy (PRESS) (1)H-MRSI using an endorectal coil. MRSI voxels were selected in the peripheral zone and combined central gland at the same location in the prostate in both measurements. Voxels with approved spectral quality were included to calculate Bland-Altman parameters for reproducibility from the choline plus creatine to citrate ratio (CC/C). The repeated spectroscopic data were also evaluated with a standardized clinical scoring system. 
Results: A total of 74 voxels were included for reproducibility analysis. The complete range of biologically interesting CC/C ratios was covered. The overall within-voxel standard deviation (SD) of the CC/C ratio of the repeated measurements was 0.13. This value is equal to the between-subject SD of noncancer prostate tissue. In {\textrangle}90\% of the voxels the standardized clinical score did not differ relevantly between the measurements. 
Conclusion: Repeated measurements of in vivo 3D (1)H-MRSI of the complete prostate at 1.5T produce equal and quantitative results. The reproducibility of the technique is high enough to provide it as a reliable tool in assessing tumor presence in the prostate.},
  author       = {Lagemaat, Miriam W and Zechmann, Christian M and Futterer, Jurgen J and Weiland, Elisabeth and Lu, Jianping and Villeirs, Geert and Holshouser, Barbara A and van Hecke, Paul and Lemort, Marc and Schlemmer, Heinz-Peter and Barentsz, Jelle O and Roell, Stefan O and Heerschap, Arend and Scheenen, Tom WJ},
  issn         = {1053-1807},
  journal      = {JOURNAL OF MAGNETIC RESONANCE IMAGING},
  keyword      = {3T,TISSUE,SEXTANT LOCALIZATION,CANCER LOCALIZATION,reproducibility,MAGNETIC-RESONANCE-SPECTROSCOPY,HUMAN BRAIN,prostate cancer,magnetic resonance spectroscopic imaging},
  language     = {eng},
  number       = {1},
  pages        = {166--173},
  title        = {Reproducibility of 3D 1H MR spectroscopic imaging of the prostate at 1.5T},
  url          = {http://dx.doi.org/10.1002/jmri.22827},
  volume       = {35},
  year         = {2012},
}

Chicago
Lagemaat, Miriam W, Christian M Zechmann, Jurgen J Futterer, Elisabeth Weiland, Jianping Lu, Geert Villeirs, Barbara A Holshouser, et al. 2012. “Reproducibility of 3D 1H MR Spectroscopic Imaging of the Prostate at 1.5T.” Journal of Magnetic Resonance Imaging 35 (1): 166–173.
APA
Lagemaat, M. W., Zechmann, C. M., Futterer, J. J., Weiland, E., Lu, J., Villeirs, G., Holshouser, B. A., et al. (2012). Reproducibility of 3D 1H MR spectroscopic imaging of the prostate at 1.5T. JOURNAL OF MAGNETIC RESONANCE IMAGING, 35(1), 166–173.
Vancouver
1.
Lagemaat MW, Zechmann CM, Futterer JJ, Weiland E, Lu J, Villeirs G, et al. Reproducibility of 3D 1H MR spectroscopic imaging of the prostate at 1.5T. JOURNAL OF MAGNETIC RESONANCE IMAGING. 2012;35(1):166–73.
MLA
Lagemaat, Miriam W, Christian M Zechmann, Jurgen J Futterer, et al. “Reproducibility of 3D 1H MR Spectroscopic Imaging of the Prostate at 1.5T.” JOURNAL OF MAGNETIC RESONANCE IMAGING 35.1 (2012): 166–173. Print.