Ghent University Academic Bibliography

Advanced

Symptom fluctuations and daily physical activity in patients with chronic fatigue syndrome: a case-control study

Mira Meeus UGent, Inge Van Eupen, Ellen Van Baarle, Valérie De Boeck, Anke Luyckx, Daphne Kos UGent and Jo Nijs (2011) ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION. 92(11). p.1820-1826
abstract
Objectives: To compare the activity pattern of patients with chronic fatigue syndrome (CFS) with healthy sedentary subjects and examine the relationship between the different parameters of performed activity (registered by an accelerometer device) and symptom severity and fluctuation (registered by questionnaires) in patients with CFS. Design: Case-control study. Participants were asked to wear an accelerometer device on the nondominant hand for 6 consecutive days. Every morning, afternoon, and evening patients scored the intensity of their pain, fatigue, and concentration difficulties on a visual analog scale. Setting: Patients were recruited from a specialized chronic fatigue clinic in the university hospital, where all subjects were invited for 2 appointments (for questionnaire and accelerometer adjustments). In between, activity data were collected in the subject's normal home environment. Participants: Female patients (n=67) with CFS and female age-matched healthy sedentary controls. Interventions: Not applicable. Main Outcome Measures: Accelerometry (average activity counts, peak activity counts, ratio peak/average, minutes spent per activity category) and symptom severity (intensity of pain, fatigue, and concentration difficulties). Results: Patients with CFS were less active, spent more time sedentary, and less time lightly active (P<.05). The course of the activity level during the registration period (P interaction>.05), peak activity, and the staggering of activities (ratio peak/average) on 1 day were not different between groups (P>.05). Negative correlations (-.242 varying to -.307) were observed for sedentary activity and the ratio with symptom severity and variation on the same and the next day. Light, moderate, and vigorous, as well as the average activity and the peak activity, were positively correlated (.242 varying to .421) with symptom severity and variation. Conclusions: The more patients with CFS are sedentary and the better activity is dispersed, the fewer symptoms and variations they experience on the same and next day. Inversely, more symptoms and variability is experienced when patients were more active that day or the previous day. The direction of these relations cannot be determined in a cross-sectional study and requires further study.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
ambulatory, Signs and symptoms, Monitoring, chronic, Fatigue syndrome, Rehabilitation, Motor activity
journal title
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
Arch. Phys. Med. Rehabil.
volume
92
issue
11
pages
1820 - 1826
Web of Science type
Article
Web of Science id
000296934600013
JCR category
REHABILITATION
JCR impact factor
2.282 (2011)
JCR rank
10/57 (2011)
JCR quartile
1 (2011)
ISSN
0003-9993
DOI
10.1016/j.apmr.2011.06.023
language
English
UGent publication?
no
classification
A1
id
2014583
handle
http://hdl.handle.net/1854/LU-2014583
date created
2012-02-01 12:05:42
date last changed
2012-02-10 14:30:51
@article{2014583,
  abstract     = {Objectives: To compare the activity pattern of patients with chronic fatigue syndrome (CFS) with healthy sedentary subjects and examine the relationship between the different parameters of performed activity (registered by an accelerometer device) and symptom severity and fluctuation (registered by questionnaires) in patients with CFS. 
Design: Case-control study. Participants were asked to wear an accelerometer device on the nondominant hand for 6 consecutive days. Every morning, afternoon, and evening patients scored the intensity of their pain, fatigue, and concentration difficulties on a visual analog scale. 
Setting: Patients were recruited from a specialized chronic fatigue clinic in the university hospital, where all subjects were invited for 2 appointments (for questionnaire and accelerometer adjustments). In between, activity data were collected in the subject's normal home environment. 
Participants: Female patients (n=67) with CFS and female age-matched healthy sedentary controls. 
Interventions: Not applicable. 
Main Outcome Measures: Accelerometry (average activity counts, peak activity counts, ratio peak/average, minutes spent per activity category) and symptom severity (intensity of pain, fatigue, and concentration difficulties). 
Results: Patients with CFS were less active, spent more time sedentary, and less time lightly active (P{\textlangle}.05). The course of the activity level during the registration period (P interaction{\textrangle}.05), peak activity, and the staggering of activities (ratio peak/average) on 1 day were not different between groups (P{\textrangle}.05). Negative correlations (-.242 varying to -.307) were observed for sedentary activity and the ratio with symptom severity and variation on the same and the next day. Light, moderate, and vigorous, as well as the average activity and the peak activity, were positively correlated (.242 varying to .421) with symptom severity and variation. 
Conclusions: The more patients with CFS are sedentary and the better activity is dispersed, the fewer symptoms and variations they experience on the same and next day. Inversely, more symptoms and variability is experienced when patients were more active that day or the previous day. The direction of these relations cannot be determined in a cross-sectional study and requires further study.},
  author       = {Meeus, Mira and Van Eupen, Inge and Van Baarle, Ellen and De Boeck, Val{\'e}rie and Luyckx, Anke and Kos, Daphne and Nijs, Jo},
  issn         = {0003-9993},
  journal      = {ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION},
  keyword      = {ambulatory,Signs and symptoms,Monitoring,chronic,Fatigue syndrome,Rehabilitation,Motor activity},
  language     = {eng},
  number       = {11},
  pages        = {1820--1826},
  title        = {Symptom fluctuations and daily physical activity in patients with chronic fatigue syndrome: a case-control study},
  url          = {http://dx.doi.org/10.1016/j.apmr.2011.06.023},
  volume       = {92},
  year         = {2011},
}

Chicago
Meeus, Mira, Inge Van Eupen, Ellen Van Baarle, Valérie De Boeck, Anke Luyckx, Daphne Kos, and Jo Nijs. 2011. “Symptom Fluctuations and Daily Physical Activity in Patients with Chronic Fatigue Syndrome: a Case-control Study.” Archives of Physical Medicine and Rehabilitation 92 (11): 1820–1826.
APA
Meeus, M., Van Eupen, I., Van Baarle, E., De Boeck, V., Luyckx, A., Kos, D., & Nijs, J. (2011). Symptom fluctuations and daily physical activity in patients with chronic fatigue syndrome: a case-control study. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION, 92(11), 1820–1826.
Vancouver
1.
Meeus M, Van Eupen I, Van Baarle E, De Boeck V, Luyckx A, Kos D, et al. Symptom fluctuations and daily physical activity in patients with chronic fatigue syndrome: a case-control study. ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION. 2011;92(11):1820–6.
MLA
Meeus, Mira, Inge Van Eupen, Ellen Van Baarle, et al. “Symptom Fluctuations and Daily Physical Activity in Patients with Chronic Fatigue Syndrome: a Case-control Study.” ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION 92.11 (2011): 1820–1826. Print.