Advanced search

The human keratinocyte two-dimensional gel protein database (update 1992): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases

(1992) ELECTROPHORESIS. 13(12). p.893-959
Author
Organization
Abstract
The master two-dimensional gel database of human keratinocytes currently lists 2980 cellular proteins (2098 isoelectric focusing, IEF; and 882 nonequilibrium pH gradient electrophoresis, NEPHGE) many of which correspond to posttranslational modifications. About 20% of all recorded proteins have been identified (protein name, organelle components, etc.) and they are listed in alphabetical order together with their M(r), pI, cellular localization and credit to the investigator (s) that aided in the identification. Also, we have listed 145 microsequenced proteins that are recorded in this database. As an aid in localizing the polypeptides we have included blow-ups of the master images (IEF, NEPHGE) displaying all the protein numbers. In the long run, the master keratinocyte database is expected to link protein and DNA sequencing and mapping information (Human Genome Program) and to provide an integrated picture of the expression levels and properties of the thousands of proteins that orchestrate various keratinocyte functions both in health and disease.
Keywords
DNA-SEQUENCE DATA, ACIDIC PROTEINS, ELECTROPHORESIS, PATTERNS, LINK, WELL

Citation

Please use this url to cite or link to this publication:

Chicago
Celis, Julio E, Hanne Holm Rasmussen, Peder Madsen, Henrik Leffers, Bent Honoré, Kurt Dejgaard, Borbala Gesser, et al. 1992. “The Human Keratinocyte Two-dimensional Gel Protein Database (update 1992): Towards an Integrated Approach to the Study of Cell Proliferation, Differentiation and Skin Diseases.” Electrophoresis 13 (12): 893–959.
APA
Celis, J. E., Rasmussen, H. H., Madsen, P., Leffers, H., Honoré, B., Dejgaard, K., Gesser, B., et al. (1992). The human keratinocyte two-dimensional gel protein database (update 1992): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases. ELECTROPHORESIS, 13(12), 893–959.
Vancouver
1.
Celis JE, Rasmussen HH, Madsen P, Leffers H, Honoré B, Dejgaard K, et al. The human keratinocyte two-dimensional gel protein database (update 1992): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases. ELECTROPHORESIS. 1992;13(12):893–959.
MLA
Celis, Julio E, Hanne Holm Rasmussen, Peder Madsen, et al. “The Human Keratinocyte Two-dimensional Gel Protein Database (update 1992): Towards an Integrated Approach to the Study of Cell Proliferation, Differentiation and Skin Diseases.” ELECTROPHORESIS 13.12 (1992): 893–959. Print.
@article{200776,
  abstract     = {The master two-dimensional gel database of human keratinocytes currently lists 2980 cellular proteins (2098 isoelectric focusing, IEF; and 882 nonequilibrium pH gradient electrophoresis, NEPHGE) many of which correspond to posttranslational modifications. About 20\% of all recorded proteins have been identified (protein name, organelle components, etc.) and they are listed in alphabetical order together with their M(r), pI, cellular localization and credit to the investigator (s) that aided in the identification. Also, we have listed 145 microsequenced proteins that are recorded in this database. As an aid in localizing the polypeptides we have included blow-ups of the master images (IEF, NEPHGE) displaying all the protein numbers. In the long run, the master keratinocyte database is expected to link protein and DNA sequencing and mapping information (Human Genome Program) and to provide an integrated picture of the expression levels and properties of the thousands of proteins that orchestrate various keratinocyte functions both in health and disease.},
  author       = {Celis, Julio E and Rasmussen, Hanne Holm and Madsen, Peder and Leffers, Henrik and Honor{\'e}, Bent and Dejgaard, Kurt and Gesser, Borbala and Olsen, Eydfinnur and Gromov, Paul and Hoffmann, Hans J and Nielsen, Morten and Celis, Ariana and Basse, Bodil and Lauridsen, Jette B and Ratz, Gitte P and Nielsen, Helle and Andersen, Annette H and Walbum, Else and Kj{\ae}rgaard, Inge and Puype, Magda and Van Damme, Jozef and Vandekerckhove, Jo{\"e}l},
  issn         = {0173-0835},
  journal      = {ELECTROPHORESIS},
  keyword      = {DNA-SEQUENCE DATA,ACIDIC PROTEINS,ELECTROPHORESIS,PATTERNS,LINK,WELL},
  language     = {eng},
  number       = {12},
  pages        = {893--959},
  title        = {The human keratinocyte two-dimensional gel protein database (update 1992): towards an integrated approach to the study of cell proliferation, differentiation and skin diseases},
  url          = {http://dx.doi.org/10.1002/elps.11501301198},
  volume       = {13},
  year         = {1992},
}

Altmetric
View in Altmetric