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Intestinal protection against challenge with transmissible gastroenteritis virus of pigs immune after infection with the porcine respiratory coronavirus

Eric Cox UGent, Maurice Pensaert and Paul Callebaut (1993) VACCINE. 11(2). p.267-272
abstract
An infection of pigs with the porcine respiratory coronavirus (PRCV) induces antibodies which neutralize the enteropathogenic transmissible gastroenteritis virus (TGEV) and PRCV to the same titre. In the present study, 10-week-old seronegative pigs (n = 8), pigs immune following TGEV inoculation (n = 4) or pigs immune following aerosol (n = 8) or intragastric inoculation (n = 4) with PRCV were challenged with TGEV. Whereas TGEV-immune pigs were completely protected against challenge, all PRCV-immune pigs showed serological evidence of TGE V replication. Nevertheless, the aerosol or intragastric inoculation with PRCV primed the humoral immune system against TGEV and the TGEV challenge induced a secondary antibody response in most PRCV-immune pigs. Furthermore, all PRCV-immune pigs showed a decrease in the duration of the excretion of infectious TGEV (0-4 days) in comparison with the duration of the virus excretion by seronegative pigs (5-6 days).
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
TRANSMISSIBLE GASTROENTERITIS VIRUS, PORCINE RESPIRATORY CORONAVIRUS, CHALLENGE, PROTECTION, IMMUNE RESPONSE, SWINE, DIFFERENTIATION, VACCINATION, SERUM
journal title
VACCINE
Vaccine
volume
11
issue
2
pages
267 - 272
Web of Science type
Article
ISSN
0264-410X
DOI
10.1016/0264-410X(93)90028-V
language
English
UGent publication?
yes
classification
A1
id
200605
handle
http://hdl.handle.net/1854/LU-200605
date created
2004-01-14 13:42:00
date last changed
2017-04-12 11:36:38
@article{200605,
  abstract     = {An infection of pigs with the porcine respiratory coronavirus (PRCV) induces antibodies which neutralize the enteropathogenic transmissible gastroenteritis virus (TGEV) and PRCV to the same titre. In the present study, 10-week-old seronegative pigs (n = 8), pigs immune following TGEV inoculation (n = 4) or pigs immune following aerosol (n = 8) or intragastric inoculation (n = 4) with PRCV were challenged with TGEV. Whereas TGEV-immune pigs were completely protected against challenge, all PRCV-immune pigs showed serological evidence of TGE V replication. Nevertheless, the aerosol or intragastric inoculation with PRCV primed the humoral immune system against TGEV and the TGEV challenge induced a secondary antibody response in most PRCV-immune pigs. Furthermore, all PRCV-immune pigs showed a decrease in the duration of the excretion of infectious TGEV (0-4 days) in comparison with the duration of the virus excretion by seronegative pigs (5-6 days).},
  author       = {Cox, Eric and Pensaert, Maurice and Callebaut, Paul},
  issn         = {0264-410X},
  journal      = {VACCINE},
  keyword      = {TRANSMISSIBLE GASTROENTERITIS VIRUS,PORCINE RESPIRATORY CORONAVIRUS,CHALLENGE,PROTECTION,IMMUNE RESPONSE,SWINE,DIFFERENTIATION,VACCINATION,SERUM},
  language     = {eng},
  number       = {2},
  pages        = {267--272},
  title        = {Intestinal protection against challenge with transmissible gastroenteritis virus of pigs immune after infection with the porcine respiratory coronavirus},
  url          = {http://dx.doi.org/10.1016/0264-410X(93)90028-V},
  volume       = {11},
  year         = {1993},
}

Chicago
Cox, Eric, Maurice Pensaert, and Paul Callebaut. 1993. “Intestinal Protection Against Challenge with Transmissible Gastroenteritis Virus of Pigs Immune After Infection with the Porcine Respiratory Coronavirus.” Vaccine 11 (2): 267–272.
APA
Cox, E., Pensaert, M., & Callebaut, P. (1993). Intestinal protection against challenge with transmissible gastroenteritis virus of pigs immune after infection with the porcine respiratory coronavirus. VACCINE, 11(2), 267–272.
Vancouver
1.
Cox E, Pensaert M, Callebaut P. Intestinal protection against challenge with transmissible gastroenteritis virus of pigs immune after infection with the porcine respiratory coronavirus. VACCINE. 1993;11(2):267–72.
MLA
Cox, Eric, Maurice Pensaert, and Paul Callebaut. “Intestinal Protection Against Challenge with Transmissible Gastroenteritis Virus of Pigs Immune After Infection with the Porcine Respiratory Coronavirus.” VACCINE 11.2 (1993): 267–272. Print.