Ghent University Academic Bibliography

Advanced

Wavelet-based functional mixed models for the analysis of lateralized readiness potentials

Tom Loeys UGent, Johan Steen UGent and Björn Van Loy UGent (2010) 20th annual meeting of the international society for clinical biostatistics, Abstracts.
abstract
Event-related potentials recorded from the human scalp using EEG can provide important information about how the human brain processes information. To unravel cognitive processes, the so-called lateralized readiness potential (LRP) has become an especially useful temporal marker within the area of chrono-psychophysiology. Simple parametric modeling of such LRP-curves is unsufficient and nonparametric approaches allowing for arbitrary functional forms are warranted. Smoothing methods using global bandwidths and penalties are often used to model such longitudinal data with curves but fail to capture spatial heterogeneity and local features like peaks. Using kernels with local bandwidths and adaptive penalties can address these issues in the single-function setting, but are not easily generalized to the multiple-function setting. Wavelet-based functional mixed models (WFMM) as proposed by Morris and Carroll (JRSS B, 2006, Vol.68, pp179-199) may offer a valuable alternative in this setting. We aim to illustrate WFMM to LRP-data from a task switching study. More specifically we are interested to determine the timepoint/latency at which a consistent divergence in LRP-signals between task repetitions and task switches can be observed and to investigate whether this latency is influenced by other factors (such as cuing type, indication requirement, ...). Repeated testing at different timepoints induces a multiple testing problem (MTP). We compare the performance of different multiple testing procedures using the pointwise posterior credible intervals versus inference from the joint posterior credible interval.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
keyword
Lateralized readiness potential (LRP), Multiple testing problem (MTP), Wavelet-based functional mixed models (WFMM)
in
20th annual meeting of the international society for clinical biostatistics, Abstracts
conference name
20th Annual Meeting of the International Society for Clinical Biostatistics (ISCB - 2010)
conference location
Montpellier, France
conference start
2010-08-29
conference end
2010-09-02
language
English
UGent publication?
yes
classification
C3
copyright statement
I have retained and own the full copyright for this publication
id
2005200
handle
http://hdl.handle.net/1854/LU-2005200
date created
2012-01-26 16:17:26
date last changed
2012-01-30 13:31:07
@inproceedings{2005200,
  abstract     = {Event-related potentials recorded from the human scalp using EEG can provide important information about how the human brain processes information. To unravel cognitive processes, the so-called lateralized readiness potential (LRP) has become an especially useful temporal marker within the area of chrono-psychophysiology. Simple parametric modeling of such LRP-curves is unsufficient and nonparametric approaches allowing for arbitrary functional forms are warranted. Smoothing methods using global bandwidths and penalties are often used to model such longitudinal data with curves but fail to capture spatial heterogeneity and local features like peaks. Using kernels with local bandwidths and adaptive penalties can address these issues in the single-function setting, but are not easily generalized to the multiple-function setting. Wavelet-based functional mixed models (WFMM) as proposed by Morris and Carroll (JRSS B, 2006, Vol.68, pp179-199) may offer a valuable alternative in this setting. We aim to illustrate WFMM to LRP-data from a task switching study. More specifically we are interested to determine the timepoint/latency at which a consistent divergence in LRP-signals between task repetitions and task switches can be observed and to investigate whether this latency is influenced by other factors (such as cuing type, indication requirement, ...). Repeated testing at different timepoints induces a multiple testing problem (MTP). We compare the performance of different multiple testing procedures using the pointwise posterior credible intervals versus inference from the joint posterior credible interval.},
  author       = {Loeys, Tom and Steen, Johan and Van Loy, Bj{\"o}rn},
  booktitle    = {20th annual meeting of the international society for clinical biostatistics, Abstracts},
  keyword      = {Lateralized readiness potential (LRP),Multiple testing problem (MTP),Wavelet-based functional mixed models (WFMM)},
  language     = {eng},
  location     = {Montpellier, France},
  title        = {Wavelet-based functional mixed models for the analysis of lateralized readiness potentials},
  year         = {2010},
}

Chicago
Loeys, Tom, Johan Steen, and Björn Van Loy. 2010. “Wavelet-based Functional Mixed Models for the Analysis of Lateralized Readiness Potentials.” In 20th Annual Meeting of the International Society for Clinical Biostatistics, Abstracts.
APA
Loeys, T., Steen, J., & Van Loy, B. (2010). Wavelet-based functional mixed models for the analysis of lateralized readiness potentials. 20th annual meeting of the international society for clinical biostatistics, Abstracts. Presented at the 20th Annual Meeting of the International Society for Clinical Biostatistics (ISCB - 2010).
Vancouver
1.
Loeys T, Steen J, Van Loy B. Wavelet-based functional mixed models for the analysis of lateralized readiness potentials. 20th annual meeting of the international society for clinical biostatistics, Abstracts. 2010.
MLA
Loeys, Tom, Johan Steen, and Björn Van Loy. “Wavelet-based Functional Mixed Models for the Analysis of Lateralized Readiness Potentials.” 20th Annual Meeting of the International Society for Clinical Biostatistics, Abstracts. 2010. Print.