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Vaccination against EHEC : insights from model in sheep

Maryam Atef Yekta (UGent) , Kris Vande Walle (UGent) , Bruno Goddeeris (UGent) , Daisy Vanrompay (UGent) and Eric Cox (UGent)
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Abstract
Enterohaemorrhagic Escherichia coli O157:H7 are zoonotic pathogens associated with haemorrhagic colitis (HC) and the haemolytic uremic syndrome (HUS). Ruminants are the main reservoir of this organism and most outbreaks of E. coli O157:H7 infections are food borne. Food contamination by ruminant manure has been reported as the primary source of human infection, therefore inhibition of E. coli O157:H7 colonization and shedding in ruminants could control the risk of human exposure to this pathogen. In the present study a vaccine based on the translocon proteins EspA and EspB and the outer membrane adhesion factor intiminγ significantly reduced faecal shedding of E. coli O157:H7 by orally infected sheep.

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Citation

Please use this url to cite or link to this publication:

MLA
Atef Yekta, Maryam et al. “Vaccination Against EHEC : Insights from Model in Sheep.” ECMIS, Abstracts. 2011. Print.
APA
Atef Yekta, M., Vande Walle, K., Goddeeris, B., Vanrompay, D., & Cox, E. (2011). Vaccination against EHEC : insights from model in sheep. ECMIS, Abstracts. Presented at the ECMIS 2011 : Escherichia coli and the Mucosal Immune System : interaction, modulation and vaccination.
Chicago author-date
Atef Yekta, Maryam, Kris Vande Walle, Bruno Goddeeris, Daisy Vanrompay, and Eric Cox. 2011. “Vaccination Against EHEC : Insights from Model in Sheep.” In ECMIS, Abstracts.
Chicago author-date (all authors)
Atef Yekta, Maryam, Kris Vande Walle, Bruno Goddeeris, Daisy Vanrompay, and Eric Cox. 2011. “Vaccination Against EHEC : Insights from Model in Sheep.” In ECMIS, Abstracts.
Vancouver
1.
Atef Yekta M, Vande Walle K, Goddeeris B, Vanrompay D, Cox E. Vaccination against EHEC : insights from model in sheep. ECMIS, Abstracts. 2011.
IEEE
[1]
M. Atef Yekta, K. Vande Walle, B. Goddeeris, D. Vanrompay, and E. Cox, “Vaccination against EHEC : insights from model in sheep,” in ECMIS, Abstracts, Ghent, Belgium, 2011.
@inproceedings{2000123,
  abstract     = {{Enterohaemorrhagic Escherichia coli O157:H7 are zoonotic pathogens associated with haemorrhagic colitis (HC) and the haemolytic uremic syndrome (HUS). Ruminants are the main reservoir of this organism and most outbreaks of E. coli O157:H7 infections are food borne. Food contamination by ruminant manure has been reported as the primary source of human infection, therefore inhibition of E. coli O157:H7 colonization and shedding in ruminants could control the risk of human exposure to this pathogen. In the present study a vaccine based on the translocon proteins EspA and EspB and the outer membrane adhesion factor intiminγ significantly reduced faecal shedding of E. coli O157:H7 by orally infected sheep.}},
  author       = {{Atef Yekta, Maryam and Vande Walle, Kris and Goddeeris, Bruno and Vanrompay, Daisy and Cox, Eric}},
  booktitle    = {{ECMIS, Abstracts}},
  language     = {{eng}},
  location     = {{Ghent, Belgium}},
  title        = {{Vaccination against EHEC : insights from model in sheep}},
  year         = {{2011}},
}