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Micro-computed tomography of the head and dentition in cadavers of clinically normal rabbits

Lieve De Rycke (UGent) , Matthieu Boone (UGent) , Annemie Van Caelenberg (UGent) , Manuel Dierick (UGent) , Luc Van Hoorebeke (UGent) , Henri van Bree (UGent) and Ingrid Gielen (UGent)
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Abstract
Objective-To describe the anatomic features of dentition and surrounding structures of the head in rabbits assessed by use of a newly developed micro-computed tomography (CT) device. Sample-Cadavers of 7 clinically normal adult Dendermonde White domestic rabbits raised for human consumption. Procedures-The rabbits were slaughtered in a slaughterhouse, flayed, and decapitated; the rabbit heads were frozen for micro-CT examination. Transverse images were obtained from the nares to the occipital condyles with a custom-designed micro-CT scanner built at the Ghent University Centre for X-ray Tomography. Scan settings were chosen to highlight bony structures on the basis of the designers' experience. The micro-CT images were reviewed, and all recognizable anatomic features were labeled. Afterward, micro-CT images were used to create 3-D reconstructions by use of a custom-developed reconstruction package and 3-D rendering with dedicated software. Results-Microstructures of the bones and teeth were clearly visible on micro-CT images. Conversely, soft tissue contrast was relatively poor on these images. Conclusions and Clinical Relevance-Micro-CT appeared to be a promising technique for appropriate diagnosis of dental disease in rabbits. Further research is needed to determine the clinical applications of micro-CT imaging.
Keywords
GUINEA-PIG, VIRTUAL HISTOLOGY, MICROCOMPUTED TOMOGRAPHY, PET RABBITS, BONE ARCHITECTURE, DENTAL DISEASE, CT, DIAGNOSIS, VISUALIZATION, CHINCHILLA

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Chicago
De Rycke, Lieve, Matthieu Boone, Annemie Van Caelenberg, Manuel Dierick, Luc Van Hoorebeke, Henri van Bree, and Ingrid Gielen. 2012. “Micro-computed Tomography of the Head and Dentition in Cadavers of Clinically Normal Rabbits.” American Journal of Veterinary Research 73 (2): 227–232.
APA
De Rycke, Lieve, Boone, M., Van Caelenberg, A., Dierick, M., Van Hoorebeke, L., van Bree, H., & Gielen, I. (2012). Micro-computed tomography of the head and dentition in cadavers of clinically normal rabbits. AMERICAN JOURNAL OF VETERINARY RESEARCH, 73(2), 227–232.
Vancouver
1.
De Rycke L, Boone M, Van Caelenberg A, Dierick M, Van Hoorebeke L, van Bree H, et al. Micro-computed tomography of the head and dentition in cadavers of clinically normal rabbits. AMERICAN JOURNAL OF VETERINARY RESEARCH. 2012;73(2):227–32.
MLA
De Rycke, Lieve, Matthieu Boone, Annemie Van Caelenberg, et al. “Micro-computed Tomography of the Head and Dentition in Cadavers of Clinically Normal Rabbits.” AMERICAN JOURNAL OF VETERINARY RESEARCH 73.2 (2012): 227–232. Print.
@article{1999507,
  abstract     = {Objective-To describe the anatomic features of dentition and surrounding structures of the head in rabbits assessed by use of a newly developed micro-computed tomography (CT) device. 
Sample-Cadavers of 7 clinically normal adult Dendermonde White domestic rabbits raised for human consumption. 
Procedures-The rabbits were slaughtered in a slaughterhouse, flayed, and decapitated; the rabbit heads were frozen for micro-CT examination. Transverse images were obtained from the nares to the occipital condyles with a custom-designed micro-CT scanner built at the Ghent University Centre for X-ray Tomography. Scan settings were chosen to highlight bony structures on the basis of the designers' experience. The micro-CT images were reviewed, and all recognizable anatomic features were labeled. Afterward, micro-CT images were used to create 3-D reconstructions by use of a custom-developed reconstruction package and 3-D rendering with dedicated software. 
Results-Microstructures of the bones and teeth were clearly visible on micro-CT images. Conversely, soft tissue contrast was relatively poor on these images. 
Conclusions and Clinical Relevance-Micro-CT appeared to be a promising technique for appropriate diagnosis of dental disease in rabbits. Further research is needed to determine the clinical applications of micro-CT imaging.},
  author       = {De Rycke, Lieve and Boone, Matthieu and Van Caelenberg, Annemie and Dierick, Manuel and Van Hoorebeke, Luc and van Bree, Henri and Gielen, Ingrid},
  issn         = {0002-9645},
  journal      = {AMERICAN JOURNAL OF VETERINARY RESEARCH},
  keyword      = {GUINEA-PIG,VIRTUAL HISTOLOGY,MICROCOMPUTED TOMOGRAPHY,PET RABBITS,BONE ARCHITECTURE,DENTAL DISEASE,CT,DIAGNOSIS,VISUALIZATION,CHINCHILLA},
  language     = {eng},
  number       = {2},
  pages        = {227--232},
  title        = {Micro-computed tomography of the head and dentition in cadavers of clinically normal rabbits},
  url          = {http://dx.doi.org/10.2460/ajvr.73.2.227},
  volume       = {73},
  year         = {2012},
}

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