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Synthesis of novel β-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure

Tamara Meiresonne UGent, Sven Mangelinckx UGent and Norbert De Kimpe UGent (2011) ORGANIC & BIOMOLECULAR CHEMISTRY. 9(20). p.7085-7091
abstract
Novel beta-aminocyclobutanecarboxylic acid derivatives were prepared via a sequential solvent-free aza-Michael addition of benzophenone imine across 3-halopropylidenemalonates and base-induced ring closure. These highly substituted cyclobutanedicarboxylic acid derivatives were subjected to a reactivity study which demonstrated the tendency of these donor-acceptor substituted four-membered rings to be converted into their corresponding ring-opened products.
Please use this url to cite or link to this publication:
author
organization
alternative title
Synthesis of novel beta-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure
year
type
journalArticle (original)
publication status
published
subject
keyword
2-AMINOCYCLOBUTANECARBOXYLIC ACID, URACIL DERIVATIVES, AMINO-ACIDS, DIPEPTIDES, TRANSFORMATION, PHOTOCYCLOADDITION, CHEMISTRY, TETRAPEPTIDE, GAMMA-PEPTIDES, FOLDAMERS
journal title
ORGANIC & BIOMOLECULAR CHEMISTRY
Org. Biomol. Chem.
volume
9
issue
20
pages
7085 - 7091
Web of Science type
Article
Web of Science id
000295889900034
JCR category
CHEMISTRY, ORGANIC
JCR impact factor
3.696 (2011)
JCR rank
11/56 (2011)
JCR quartile
1 (2011)
ISSN
1477-0520
DOI
10.1039/c1ob05872j
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1997584
handle
http://hdl.handle.net/1854/LU-1997584
date created
2012-01-19 21:09:07
date last changed
2012-07-14 00:30:43
@article{1997584,
  abstract     = {Novel beta-aminocyclobutanecarboxylic acid derivatives were prepared via a sequential solvent-free aza-Michael addition of benzophenone imine across 3-halopropylidenemalonates and base-induced ring closure. These highly substituted cyclobutanedicarboxylic acid derivatives were subjected to a reactivity study which demonstrated the tendency of these donor-acceptor substituted four-membered rings to be converted into their corresponding ring-opened products.},
  author       = {Meiresonne, Tamara and Mangelinckx, Sven and De Kimpe, Norbert},
  issn         = {1477-0520},
  journal      = {ORGANIC \& BIOMOLECULAR CHEMISTRY},
  keyword      = {2-AMINOCYCLOBUTANECARBOXYLIC ACID,URACIL DERIVATIVES,AMINO-ACIDS,DIPEPTIDES,TRANSFORMATION,PHOTOCYCLOADDITION,CHEMISTRY,TETRAPEPTIDE,GAMMA-PEPTIDES,FOLDAMERS},
  language     = {eng},
  number       = {20},
  pages        = {7085--7091},
  title        = {Synthesis of novel \ensuremath{\beta}-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure},
  url          = {http://dx.doi.org/10.1039/c1ob05872j},
  volume       = {9},
  year         = {2011},
}

Chicago
Meiresonne, Tamara, Sven Mangelinckx, and Norbert De Kimpe. 2011. “Synthesis of Novel Β-aminocyclobutanecarboxylic Acid Derivatives by a Solvent-free aza-Michael Addition and Subsequent Ring Closure.” Organic & Biomolecular Chemistry 9 (20): 7085–7091.
APA
Meiresonne, T., Mangelinckx, S., & De Kimpe, N. (2011). Synthesis of novel β-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure. ORGANIC & BIOMOLECULAR CHEMISTRY, 9(20), 7085–7091.
Vancouver
1.
Meiresonne T, Mangelinckx S, De Kimpe N. Synthesis of novel β-aminocyclobutanecarboxylic acid derivatives by a solvent-free aza-Michael addition and subsequent ring closure. ORGANIC & BIOMOLECULAR CHEMISTRY. 2011;9(20):7085–91.
MLA
Meiresonne, Tamara, Sven Mangelinckx, and Norbert De Kimpe. “Synthesis of Novel Β-aminocyclobutanecarboxylic Acid Derivatives by a Solvent-free aza-Michael Addition and Subsequent Ring Closure.” ORGANIC & BIOMOLECULAR CHEMISTRY 9.20 (2011): 7085–7091. Print.