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Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection

Asli Kumcu (UGent) , Ljiljana Platisa (UGent) , Ivana Despotovic (UGent) , Ewout Vansteenkiste (UGent) , Aleksandra Pizurica (UGent) , Karel Deblaere (UGent) and Wilfried Philips (UGent)
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Abstract
In this work we aim to improve the detection of Focal Cortical Dysplasia on MRI images using a multimodal approach. We propose to estimate the thickness of the cortex jointly using partial volume maps of T1-weighted MPRAGE and T2- weighted FLAIR images by fitting spheres into the gray matter of the brain such that the amount of probability-weighted gray matter contained in each sphere is maximized. Results on nine patients show that the FCD lesions for all patients could be detected using the multimodal approach compared to T1 alone (FCD detected in only 7 patients) and Freesurfer (4 patients).
Keywords
FCD, MRI

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Citation

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Chicago
Kumcu, Asli, Ljiljana Platisa, Ivana Despotovic, Ewout Vansteenkiste, Aleksandra Pizurica, Karel Deblaere, and Wilfried Philips. 2012. “Multi-modal Measurement of Cortical Thickness in Brain MRI for Focal Cortical Dysplasia Detection.” In Fourth Annual Meeting of the ISMRM Benelux Chapter, 70–70.
APA
Kumcu, A., Platisa, L., Despotovic, I., Vansteenkiste, E., Pizurica, A., Deblaere, K., & Philips, W. (2012). Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection. Fourth annual meeting of the ISMRM Benelux Chapter (pp. 70–70). Presented at the 4th Annual meeting of the ISMRM Benelux Chapter.
Vancouver
1.
Kumcu A, Platisa L, Despotovic I, Vansteenkiste E, Pizurica A, Deblaere K, et al. Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection. Fourth annual meeting of the ISMRM Benelux Chapter. 2012. p. 70–70.
MLA
Kumcu, Asli, Ljiljana Platisa, Ivana Despotovic, et al. “Multi-modal Measurement of Cortical Thickness in Brain MRI for Focal Cortical Dysplasia Detection.” Fourth Annual Meeting of the ISMRM Benelux Chapter. 2012. 70–70. Print.
@inproceedings{1995464,
  abstract     = {In this work we aim to improve the detection of Focal Cortical Dysplasia on MRI images using a multimodal approach. We propose to estimate the thickness of the cortex jointly using partial volume maps of T1-weighted MPRAGE and T2- weighted FLAIR images by fitting spheres into the gray matter of the brain such that the amount of probability-weighted gray matter contained in each sphere is maximized.  Results on nine patients show that the FCD lesions for all patients could be detected using the multimodal approach compared to T1 alone (FCD detected in only 7 patients) and Freesurfer (4 patients).},
  articleno    = {abstract PT1-18},
  author       = {Kumcu, Asli and Platisa, Ljiljana and Despotovic, Ivana and Vansteenkiste, Ewout and Pizurica, Aleksandra and Deblaere, Karel and Philips, Wilfried},
  booktitle    = {Fourth annual meeting of the ISMRM Benelux Chapter},
  keyword      = {FCD,MRI},
  language     = {eng},
  location     = {Leuven, Belgium},
  pages        = {abstract PT1-18:70--abstract PT1-18:70},
  title        = {Multi-modal measurement of cortical thickness in brain MRI for Focal Cortical Dysplasia detection},
  year         = {2012},
}