Ghent University Academic Bibliography

@article{1984182,
  abstract     = {The engagement of inhibitory receptors specific for major histocompatibility complex class I (MHC-I) molecules educates natural killer (NK) cells, meaning the improvement of the response of activation receptors to subsequent stimulation. It is not known whether inhibitory MHC-I receptors educate only NK cells or whether they improve the responsiveness of all cell types, which express them. To address this issue, we analyzed the expression of inhibitory MHC-I receptors on intestinal intraepithelial lymphocytes (iIELs) and show that T-cell receptor (TCR)-alpha beta CD8 alpha alpha iIELs express multiple inhibitory receptors specific for MHC-I molecules, including CD94/NKG2A, Ly49A, and Ly49G2. However, the presence of MHC-I ligand for these receptors did not improve the response of iIELs to activation via the TCR. The absence of iIEL education by MHC-I receptors was not related to a lack of inhibitory function of these receptors in iIELs and a failure of these receptors to couple to the TCR. Thus, unlike NK cells, iIELs do not undergo an MHC-I-guided education process. These data suggest that education is an NK cell-specific function of inhibitory MHC-I receptors.},
  author       = {Taveirne, Sylvie and Filtjens, Jessica and Van Ammel, Els and De Colvenaer, Veerle and Kerre, Tessa and Taghon, Tom and Vandekerckhove, Bart and Plum, Jean and Held, Werner and Leclercq, Georges},
  issn         = {0006-4971},
  journal      = {BLOOD},
  keyword      = {MOLECULES,RESPONSIVENESS,EXPRESSION,LY49 RECEPTORS,SELF-TOLERANCE,NATURAL-KILLER-CELLS,GUT,CIS,IDENTIFICATION,ENVIRONMENT},
  language     = {eng},
  number       = {2},
  pages        = {339--347},
  title        = {Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8\ensuremath{\alpha}\ensuremath{\alpha} intestinal intraepithelial T lymphocytes},
  url          = {http://dx.doi.org/10.1182/blood-2011-01-331124},
  volume       = {118},
  year         = {2011},
}

Chicago

Taveirne, Sylvie, Jessica Filtjens, Els Van Ammel, Veerle De Colvenaer, Tessa Kerre, Tom Taghon, Bart Vandekerckhove, Jean Plum, Werner Held, and Georges Leclercq. 2011. “Inhibitory Receptors Specific for MHC Class I Educate Murine NK Cells but Not CD8αα Intestinal Intraepithelial T Lymphocytes.” Blood 118 (2): 339–347.

APA

Taveirne, S., Filtjens, J., Van Ammel, E., De Colvenaer, V., Kerre, T., Taghon, T., Vandekerckhove, B., et al. (2011). Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes. BLOOD, 118(2), 339–347.

Vancouver

1.

Taveirne S, Filtjens J, Van Ammel E, De Colvenaer V, Kerre T, Taghon T, et al. Inhibitory receptors specific for MHC class I educate murine NK cells but not CD8αα intestinal intraepithelial T lymphocytes. BLOOD. 2011;118(2):339–47.

MLA

Taveirne, Sylvie, Jessica Filtjens, Els Van Ammel, et al. “Inhibitory Receptors Specific for MHC Class I Educate Murine NK Cells but Not CD8αα Intestinal Intraepithelial T Lymphocytes.” BLOOD 118.2 (2011): 339–347. Print.