Ghent University Academic Bibliography

Advanced

Virological surveillance and preliminary antigenic characterization of influenza viruses in pigs in five European countries from 2006 to 2008

CS Kyriakis, IH Brown, E Foni, G Kuntz-Simon, J Maldonado, F Madec, SC Essen, C Chiapponi and Kristien Van Reeth UGent (2011) ZOONOSES AND PUBLIC HEALTH. 58(2). p.93-101
abstract
This study presents the results of the virological surveillance for swine influenza viruses (SIVs) in Belgium, UK, Italy, France and Spain from 2006 to 2008. Our major aims were to clarify the occurrence of the three SIV subtypes - H1N1, H3N2 and H1N2 - at regional levels, to identify novel reassortant viruses and to antigenically compare SIVs with human H1N1 and H3N2 influenza viruses. Lung tissue and/or nasal swabs from outbreaks of acute respiratory disease in pigs were investigated by virus isolation. The hemagglutinin (HA) and neuraminidase (NA) subtypes were determined using standard methods. Of the total 169 viruses, 81 were classified as 'avian-like' H1N1, 36 as human-like H3N2 and 47 as human-like H1N2. Only five novel reassortant viruses were identified: two H1N1 viruses had a human-like HA and three H1N2 viruses an avian-like HA. All three SIV subtypes were detected in Belgium, Italy and Spain, while only H1N1 and H1N2 viruses were found in UK and Northwestern France. Cross-hemagglutination inhibition (HI) tests with hyperimmune sera against selected older and recent human influenza viruses showed a strong antigenic relationship between human H1N1 and H3N2 viruses from the 1980s and H1N2 and H3N2 human-like SIVs, confirming their common origin. However, antisera against human viruses isolated during the last decade did not react with currently circulating H1 or H3 SIVs, suggesting that especially young people may be, to some degree, susceptible to SIV infections.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
keyword
BELGIUM, DISEASE, PROTECTION, SWINE INFLUENZA, A VIRUS, Europe, GREAT-BRITAIN, antigenic characterization, virological surveillance, pigs, Swine influenza virus, VACCINATION, H3N2, EVOLUTION, H1N2 SUBTYPE
journal title
ZOONOSES AND PUBLIC HEALTH
Zoonoses Public Health
volume
58
issue
2
pages
93 - 101
Web of Science type
Article
Web of Science id
000287146800003
JCR category
VETERINARY SCIENCES
JCR impact factor
1.895 (2011)
JCR rank
21/141 (2011)
JCR quartile
1 (2011)
ISSN
1863-1959
DOI
10.1111/j.1863-2378.2009.01301.x
language
English
UGent publication?
yes
classification
A1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1983191
handle
http://hdl.handle.net/1854/LU-1983191
date created
2012-01-11 11:42:57
date last changed
2012-01-16 14:22:09
@article{1983191,
  abstract     = {This study presents the results of the virological surveillance for swine influenza viruses (SIVs) in Belgium, UK, Italy, France and Spain from 2006 to 2008. Our major aims were to clarify the occurrence of the three SIV subtypes - H1N1, H3N2 and H1N2 - at regional levels, to identify novel reassortant viruses and to antigenically compare SIVs with human H1N1 and H3N2 influenza viruses. Lung tissue and/or nasal swabs from outbreaks of acute respiratory disease in pigs were investigated by virus isolation. The hemagglutinin (HA) and neuraminidase (NA) subtypes were determined using standard methods. Of the total 169 viruses, 81 were classified as 'avian-like' H1N1, 36 as human-like H3N2 and 47 as human-like H1N2. Only five novel reassortant viruses were identified: two H1N1 viruses had a human-like HA and three H1N2 viruses an avian-like HA. All three SIV subtypes were detected in Belgium, Italy and Spain, while only H1N1 and H1N2 viruses were found in UK and Northwestern France. Cross-hemagglutination inhibition (HI) tests with hyperimmune sera against selected older and recent human influenza viruses showed a strong antigenic relationship between human H1N1 and H3N2 viruses from the 1980s and H1N2 and H3N2 human-like SIVs, confirming their common origin. However, antisera against human viruses isolated during the last decade did not react with currently circulating H1 or H3 SIVs, suggesting that especially young people may be, to some degree, susceptible to SIV infections.},
  author       = {Kyriakis, CS and Brown, IH and Foni, E and Kuntz-Simon, G and Maldonado, J and Madec, F and Essen, SC and Chiapponi, C and Van Reeth, Kristien},
  issn         = {1863-1959},
  journal      = {ZOONOSES AND PUBLIC HEALTH},
  keyword      = {BELGIUM,DISEASE,PROTECTION,SWINE INFLUENZA,A VIRUS,Europe,GREAT-BRITAIN,antigenic characterization,virological surveillance,pigs,Swine influenza virus,VACCINATION,H3N2,EVOLUTION,H1N2 SUBTYPE},
  language     = {eng},
  number       = {2},
  pages        = {93--101},
  title        = {Virological surveillance and preliminary antigenic characterization of influenza viruses in pigs in five European countries from 2006 to 2008},
  url          = {http://dx.doi.org/10.1111/j.1863-2378.2009.01301.x},
  volume       = {58},
  year         = {2011},
}

Chicago
Kyriakis, CS, IH Brown, E Foni, G Kuntz-Simon, J Maldonado, F Madec, SC Essen, C Chiapponi, and Kristien Van Reeth. 2011. “Virological Surveillance and Preliminary Antigenic Characterization of Influenza Viruses in Pigs in Five European Countries from 2006 to 2008.” Zoonoses and Public Health 58 (2): 93–101.
APA
Kyriakis, C., Brown, I., Foni, E., Kuntz-Simon, G., Maldonado, J., Madec, F., Essen, S., et al. (2011). Virological surveillance and preliminary antigenic characterization of influenza viruses in pigs in five European countries from 2006 to 2008. ZOONOSES AND PUBLIC HEALTH, 58(2), 93–101.
Vancouver
1.
Kyriakis C, Brown I, Foni E, Kuntz-Simon G, Maldonado J, Madec F, et al. Virological surveillance and preliminary antigenic characterization of influenza viruses in pigs in five European countries from 2006 to 2008. ZOONOSES AND PUBLIC HEALTH. 2011;58(2):93–101.
MLA
Kyriakis, CS, IH Brown, E Foni, et al. “Virological Surveillance and Preliminary Antigenic Characterization of Influenza Viruses in Pigs in Five European Countries from 2006 to 2008.” ZOONOSES AND PUBLIC HEALTH 58.2 (2011): 93–101. Print.