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Evaluation of a propofol and remifentanil interaction model for predictive control of anesthesia induction

Clara-Mihaela Ionescu UGent, Robain De Keyser UGent and Michel Struys UGent (2011) 2011 50th IEEE Conference on decision and control and European control conference (CDC-ECC). p.7374-7379
abstract
This paper introduces a simplified linear interaction model between two drugs, namely Propofol and Remifentanil, which will be used in a model based predictive control algorithm for (nonlinear) automatic induction and regulation of DOA. Depth of anesthesia (DOA) is evaluated by means of the Bispectral index (BIS). The simulation tests are performed on a set of 24 virtually generated realistic patient models. The results are promising and the performance of the controller shows a high-efficiency, optimal dosage of the two drugs in order to achieve the desired BIS reference.
Please use this url to cite or link to this publication:
author
organization
year
type
conference
publication status
published
subject
keyword
DRUG-DELIVERY, BISPECTRAL INDEX, PHARMACODYNAMICS, PHARMACOKINETICS, AGE
in
2011 50th IEEE Conference on decision and control and European control conference (CDC-ECC)
pages
7374 - 7379
publisher
IEEE
place of publication
New York, NY, USA
conference name
50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC)
conference location
Orlando, FL, USA
conference start
2011-12-12
conference end
2011-12-15
Web of Science type
Proceedings Paper
Web of Science id
000303506208001
ISBN
9781612848013
9781612847993
language
English
UGent publication?
yes
classification
P1
copyright statement
I have transferred the copyright for this publication to the publisher
id
1981555
handle
http://hdl.handle.net/1854/LU-1981555
date created
2012-01-10 11:50:29
date last changed
2013-07-18 10:58:00
@inproceedings{1981555,
  abstract     = {This paper introduces a simplified linear interaction model between two drugs, namely Propofol and Remifentanil, which will be used in a model based predictive control algorithm for (nonlinear) automatic induction and regulation of DOA. Depth of anesthesia (DOA) is evaluated by means of the Bispectral index (BIS). The simulation tests are performed on a set of 24 virtually generated realistic patient models. The results are promising and the performance of the controller shows a high-efficiency, optimal dosage of the two drugs in order to achieve the desired BIS reference.},
  author       = {Ionescu, Clara-Mihaela and De Keyser, Robain and Struys, Michel},
  booktitle    = {2011 50th IEEE Conference on decision and control and European control conference (CDC-ECC)},
  isbn         = {9781612848013},
  keyword      = {DRUG-DELIVERY,BISPECTRAL INDEX,PHARMACODYNAMICS,PHARMACOKINETICS,AGE},
  language     = {eng},
  location     = {Orlando, FL, USA},
  pages        = {7374--7379},
  publisher    = {IEEE},
  title        = {Evaluation of a propofol and remifentanil interaction model for predictive control of anesthesia induction},
  year         = {2011},
}

Chicago
Ionescu, Clara-Mihaela, Robain De Keyser, and Michel Struys. 2011. “Evaluation of a Propofol and Remifentanil Interaction Model for Predictive Control of Anesthesia Induction.” In 2011 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC), 7374–7379. New York, NY, USA: IEEE.
APA
Ionescu, C.-M., De Keyser, R., & Struys, M. (2011). Evaluation of a propofol and remifentanil interaction model for predictive control of anesthesia induction. 2011 50th IEEE Conference on decision and control and European control conference (CDC-ECC) (pp. 7374–7379). Presented at the 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC), New York, NY, USA: IEEE.
Vancouver
1.
Ionescu C-M, De Keyser R, Struys M. Evaluation of a propofol and remifentanil interaction model for predictive control of anesthesia induction. 2011 50th IEEE Conference on decision and control and European control conference (CDC-ECC). New York, NY, USA: IEEE; 2011. p. 7374–9.
MLA
Ionescu, Clara-Mihaela, Robain De Keyser, and Michel Struys. “Evaluation of a Propofol and Remifentanil Interaction Model for Predictive Control of Anesthesia Induction.” 2011 50th IEEE Conference on Decision and Control and European Control Conference (CDC-ECC). New York, NY, USA: IEEE, 2011. 7374–7379. Print.