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α,α-Cyclobisalkylation of aldehydes via ω-haloaldimines

(1994) TETRAHEDRON LETTERS. 35(22). p.3763-3766
Author
Organization
Abstract
The construction of a cycloalkyl ring at the alpha-position of aldehydes by cyclization of omega-haloaldimines is described. Alkylation of the corresponding aldimines with alpha,omega-dihaloalkanes followed by treatment with LDA results in a convenient access to alpha,alpha-cyclobisalkylated aldimines which are hydrolyzed to the alpha,alpha-cycloalkylaldehydes.

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Chicago
Stevens, Christian, Norbert De Kimpe, and Alan R Katritzky. 1994. “α,α-Cyclobisalkylation of Aldehydes via Ω-haloaldimines.” Tetrahedron Letters 35 (22): 3763–3766.
APA
Stevens, Christian, De Kimpe, N., & Katritzky, A. R. (1994). α,α-Cyclobisalkylation of aldehydes via ω-haloaldimines. TETRAHEDRON LETTERS, 35(22), 3763–3766.
Vancouver
1.
Stevens C, De Kimpe N, Katritzky AR. α,α-Cyclobisalkylation of aldehydes via ω-haloaldimines. TETRAHEDRON LETTERS. 1994;35(22):3763–6.
MLA
Stevens, Christian, Norbert De Kimpe, and Alan R Katritzky. “α,α-Cyclobisalkylation of Aldehydes via Ω-haloaldimines.” TETRAHEDRON LETTERS 35.22 (1994): 3763–3766. Print.
@article{198100,
  abstract     = {The construction of a cycloalkyl ring at the alpha-position of aldehydes by cyclization of omega-haloaldimines is described. Alkylation of the corresponding aldimines with alpha,omega-dihaloalkanes followed by treatment with LDA results in a convenient access to alpha,alpha-cyclobisalkylated aldimines which are hydrolyzed to the alpha,alpha-cycloalkylaldehydes.},
  author       = {Stevens, Christian and De Kimpe, Norbert and Katritzky, Alan R},
  issn         = {0040-4039},
  journal      = {TETRAHEDRON LETTERS},
  language     = {eng},
  number       = {22},
  pages        = {3763--3766},
  title        = {\ensuremath{\alpha},\ensuremath{\alpha}-Cyclobisalkylation of aldehydes via \ensuremath{\omega}-haloaldimines},
  url          = {http://dx.doi.org/10.1016/S0040-4039(00)73093-0},
  volume       = {35},
  year         = {1994},
}

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