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Unbreakable codes in electrospun fibers to stop medicine counterfeiting

Chaobo Huang, Bart Lucas UGent, Chris Vervaet UGent, Kevin Braeckmans UGent, Serge Van Calenbergh UGent, Izet Karalic UGent, Mado Vandewoestyne UGent, Dieter Deforce UGent, Jo Demeester UGent and Stefaan De Smedt UGent (2010) JOURNAL OF CONTROLLED RELEASE. 148(1). p.e13-e15
abstract
Health organizations claim that there should be 'zero tolerance' for counterfeit medicines, yet the problem is growing worldwide [1-3]. This report proposes one viable solution: digitally encode polymers, which already form a major class of pharmaceutical excipients, and place them within tablets. Fluorescent polymer solutions can easily be electrospun into micron sized fibers and subsequently encoded by a photobleaching process. We have shown that, provided the physicochemical interactions between the fluorophore and the polymer are favourable, amorphous polymer fibers can be encoded with long lasting digital codes.
Please use this url to cite or link to this publication:
author
organization
year
type
conference (meetingAbstract)
publication status
published
subject
in
JOURNAL OF CONTROLLED RELEASE
J. Control. Release
volume
148
issue
1
pages
e13 - e15
Web of Science type
Meeting Abstract
Web of Science id
000296426400006
JCR category
PHARMACOLOGY & PHARMACY
JCR impact factor
7.164 (2010)
JCR rank
10/249 (2010)
JCR quartile
1 (2010)
ISSN
0168-3659
DOI
10.1016/j.jconrel.2010.07.007
language
English
UGent publication?
yes
classification
C3
copyright statement
I have transferred the copyright for this publication to the publisher
id
1978585
handle
http://hdl.handle.net/1854/LU-1978585
date created
2012-01-05 10:35:54
date last changed
2016-12-19 15:36:40
@inproceedings{1978585,
  abstract     = {Health organizations claim that there should be 'zero tolerance' for counterfeit medicines, yet the problem is growing worldwide [1-3]. This report proposes one viable solution: digitally encode polymers, which already form a major class of pharmaceutical excipients, and place them within tablets. Fluorescent polymer solutions can easily be electrospun into micron sized fibers and subsequently encoded by a photobleaching process. We have shown that, provided the physicochemical interactions between the fluorophore and the polymer are favourable, amorphous polymer fibers can be encoded with long lasting digital codes.},
  author       = {Huang, Chaobo and Lucas, Bart and Vervaet, Chris and Braeckmans, Kevin and Van Calenbergh, Serge and Karalic, Izet and Vandewoestyne, Mado and Deforce, Dieter and Demeester, Jo and De Smedt, Stefaan},
  booktitle    = {JOURNAL OF CONTROLLED RELEASE},
  issn         = {0168-3659},
  language     = {eng},
  number       = {1},
  pages        = {e13--e15},
  title        = {Unbreakable codes in electrospun fibers to stop medicine counterfeiting},
  url          = {http://dx.doi.org/10.1016/j.jconrel.2010.07.007},
  volume       = {148},
  year         = {2010},
}

Chicago
Huang, Chaobo, Bart Lucas, Chris Vervaet, Kevin Braeckmans, Serge Van Calenbergh, Izet Karalic, Mado Vandewoestyne, Dieter Deforce, Jo Demeester, and Stefaan De Smedt. 2010. “Unbreakable Codes in Electrospun Fibers to Stop Medicine Counterfeiting.” In Journal of Controlled Release, 148:e13–e15.
APA
Huang, Chaobo, Lucas, B., Vervaet, C., Braeckmans, K., Van Calenbergh, S., Karalic, I., Vandewoestyne, M., et al. (2010). Unbreakable codes in electrospun fibers to stop medicine counterfeiting. JOURNAL OF CONTROLLED RELEASE (Vol. 148, pp. e13–e15).
Vancouver
1.
Huang C, Lucas B, Vervaet C, Braeckmans K, Van Calenbergh S, Karalic I, et al. Unbreakable codes in electrospun fibers to stop medicine counterfeiting. JOURNAL OF CONTROLLED RELEASE. 2010. p. e13–e15.
MLA
Huang, Chaobo, Bart Lucas, Chris Vervaet, et al. “Unbreakable Codes in Electrospun Fibers to Stop Medicine Counterfeiting.” Journal of Controlled Release. Vol. 148. 2010. e13–e15. Print.