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Unbreakable codes in electrospun fibers to stop medicine counterfeiting

Chaobo Huang (UGent) , Bart Lucas (UGent) , Chris Vervaet (UGent) , Kevin Braeckmans (UGent) , Serge Van Calenbergh (UGent) , Izet Karalic (UGent) , Mado Vandewoestyne (UGent) , Dieter Deforce (UGent) , Jo Demeester (UGent) and Stefaan De Smedt (UGent)
(2010) JOURNAL OF CONTROLLED RELEASE. 148(1). p.e13-e15
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Abstract
Health organizations claim that there should be 'zero tolerance' for counterfeit medicines, yet the problem is growing worldwide [1-3]. This report proposes one viable solution: digitally encode polymers, which already form a major class of pharmaceutical excipients, and place them within tablets. Fluorescent polymer solutions can easily be electrospun into micron sized fibers and subsequently encoded by a photobleaching process. We have shown that, provided the physicochemical interactions between the fluorophore and the polymer are favourable, amorphous polymer fibers can be encoded with long lasting digital codes.

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Chicago
Huang, Chaobo, Bart Lucas, Chris Vervaet, Kevin Braeckmans, Serge Van Calenbergh, Izet Karalic, Mado Vandewoestyne, Dieter Deforce, Jo Demeester, and Stefaan De Smedt. 2010. “Unbreakable Codes in Electrospun Fibers to Stop Medicine Counterfeiting.” In Journal of Controlled Release, 148:e13–e15.
APA
Huang, Chaobo, Lucas, B., Vervaet, C., Braeckmans, K., Van Calenbergh, S., Karalic, I., Vandewoestyne, M., et al. (2010). Unbreakable codes in electrospun fibers to stop medicine counterfeiting. JOURNAL OF CONTROLLED RELEASE (Vol. 148, pp. e13–e15).
Vancouver
1.
Huang C, Lucas B, Vervaet C, Braeckmans K, Van Calenbergh S, Karalic I, et al. Unbreakable codes in electrospun fibers to stop medicine counterfeiting. JOURNAL OF CONTROLLED RELEASE. 2010. p. e13–e15.
MLA
Huang, Chaobo, Bart Lucas, Chris Vervaet, et al. “Unbreakable Codes in Electrospun Fibers to Stop Medicine Counterfeiting.” Journal of Controlled Release. Vol. 148. 2010. e13–e15. Print.
@inproceedings{1978585,
  abstract     = {Health organizations claim that there should be 'zero tolerance' for counterfeit medicines, yet the problem is growing worldwide [1-3]. This report proposes one viable solution: digitally encode polymers, which already form a major class of pharmaceutical excipients, and place them within tablets. Fluorescent polymer solutions can easily be electrospun into micron sized fibers and subsequently encoded by a photobleaching process. We have shown that, provided the physicochemical interactions between the fluorophore and the polymer are favourable, amorphous polymer fibers can be encoded with long lasting digital codes.},
  author       = {Huang, Chaobo and Lucas, Bart and Vervaet, Chris and Braeckmans, Kevin and Van Calenbergh, Serge and Karalic, Izet and Vandewoestyne, Mado and Deforce, Dieter and Demeester, Jo and De Smedt, Stefaan},
  booktitle    = {JOURNAL OF CONTROLLED RELEASE},
  issn         = {0168-3659},
  language     = {eng},
  number       = {1},
  pages        = {e13--e15},
  title        = {Unbreakable codes in electrospun fibers to stop medicine counterfeiting},
  url          = {http://dx.doi.org/10.1016/j.jconrel.2010.07.007},
  volume       = {148},
  year         = {2010},
}

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