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Divergent synthetic approach to 6''-modified α-GalCer analogues

(2011) ORGANIC & BIOMOLECULAR CHEMISTRY. 9(24). p.8413-8421
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Abstract
A synthetic approach is presented for the synthesis of galacturonic acid and D-fucosyl modified KRN7000. The approach allows for late-stage functionalisation of both the sugar 6 ''-OH and the sphingosine amino groups, which enables convenient synthesis of promising 6 ''-modified KRN7000 analogues.
Keywords
KRN7000, CELL STIMULATING PROPERTIES, KILLER T-CELLS, NKT CELLS, RHAMNOGALACTURONAN-I, GALACTOSYL CERAMIDE, RECOGNITION, GLYCOLIPIDS, PHASE-I, INKT CELLS

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MLA
Pauwels, Nora, et al. “Divergent Synthetic Approach to 6"-Modified α-GalCer Analogues.” ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, no. 24, 2011, pp. 8413–21, doi:10.1039/c1ob06235b.
APA
Pauwels, N., ASPESLAGH, S., Vanhoenacker, G., Sandra, K., Yu, E. D., Zajonc, D. M., … Van Calenbergh, S. (2011). Divergent synthetic approach to 6"-modified α-GalCer analogues. ORGANIC & BIOMOLECULAR CHEMISTRY, 9(24), 8413–8421. https://doi.org/10.1039/c1ob06235b
Chicago author-date
Pauwels, Nora, SANDRINE ASPESLAGH, Gerd Vanhoenacker, Koen Sandra, Esther D Yu, Dirk M Zajonc, Dirk Elewaut, Bruno Linclau, and Serge Van Calenbergh. 2011. “Divergent Synthetic Approach to 6"-Modified α-GalCer Analogues.” ORGANIC & BIOMOLECULAR CHEMISTRY 9 (24): 8413–21. https://doi.org/10.1039/c1ob06235b.
Chicago author-date (all authors)
Pauwels, Nora, SANDRINE ASPESLAGH, Gerd Vanhoenacker, Koen Sandra, Esther D Yu, Dirk M Zajonc, Dirk Elewaut, Bruno Linclau, and Serge Van Calenbergh. 2011. “Divergent Synthetic Approach to 6"-Modified α-GalCer Analogues.” ORGANIC & BIOMOLECULAR CHEMISTRY 9 (24): 8413–8421. doi:10.1039/c1ob06235b.
Vancouver
1.
Pauwels N, ASPESLAGH S, Vanhoenacker G, Sandra K, Yu ED, Zajonc DM, et al. Divergent synthetic approach to 6"-modified α-GalCer analogues. ORGANIC & BIOMOLECULAR CHEMISTRY. 2011;9(24):8413–21.
IEEE
[1]
N. Pauwels et al., “Divergent synthetic approach to 6"-modified α-GalCer analogues,” ORGANIC & BIOMOLECULAR CHEMISTRY, vol. 9, no. 24, pp. 8413–8421, 2011.
@article{1976065,
  abstract     = {{A synthetic approach is presented for the synthesis of galacturonic acid and D-fucosyl modified KRN7000. The approach allows for late-stage functionalisation of both the sugar 6 ''-OH and the sphingosine amino groups, which enables convenient synthesis of promising 6 ''-modified KRN7000 analogues.}},
  author       = {{Pauwels, Nora and ASPESLAGH, SANDRINE and Vanhoenacker, Gerd and Sandra, Koen and Yu, Esther D and Zajonc, Dirk M and Elewaut, Dirk and Linclau, Bruno and Van Calenbergh, Serge}},
  issn         = {{1477-0520}},
  journal      = {{ORGANIC & BIOMOLECULAR CHEMISTRY}},
  keywords     = {{KRN7000,CELL STIMULATING PROPERTIES,KILLER T-CELLS,NKT CELLS,RHAMNOGALACTURONAN-I,GALACTOSYL CERAMIDE,RECOGNITION,GLYCOLIPIDS,PHASE-I,INKT CELLS}},
  language     = {{eng}},
  number       = {{24}},
  pages        = {{8413--8421}},
  title        = {{Divergent synthetic approach to 6''-modified α-GalCer analogues}},
  url          = {{http://dx.doi.org/10.1039/c1ob06235b}},
  volume       = {{9}},
  year         = {{2011}},
}

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