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More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients

Jurgen De Kimpe, Rita Cornelis (UGent) , L. Mees, Stijn Van Lierde and Raymond Vanholder (UGent)
(1993) AMERICAN JOURNAL OF NEPHROLOGY. 13(6). p.429-434
Author
Organization
Abstract
Arsenic concentrations were determined in serum and packed cells of 7 chronic hemodialysis patients, in fresh dialysate and in a heparin solution. The analytical technique was radiochemical neutron activation analysis. The accuracy of the method was tested by the analysis of As in certified reference materials. Patients showed elevated serum and packed cell arsenic concentrations compared with controls (serum, range: 2.3-79.8 ng As/ml, median: 11.5 ng As/ml; versus range: 0.132-4.783 ng As/ml, median: 0.38 ng As/ml; packed cells, range: 2.1-68.4 ng As/g, median: 9.5 ng As/g; versus range: 0.51-14.44 ng As/g, median: 3.17 ng As/g). Arsenic concentrations remained unaltered, before versus after a single hemodialysis treatment. The arsenic contents of serum and packed cells were significantly correlated (n = 7, r = 0.96, p < 0.05). No arsenic could be detected in the heparin solution or in the dialysate.
Keywords
ARSENIC, CHRONIC RENAL FAILURE, CHRONIC HEMODIALYSIS, SERUM, PACKED CELLS, RADIOCHEMICAL NEUTRON ACTIVATION ANALYSIS, BIOLOGICAL REFERENCE MATERIAL, TRACE-ELEMENTS

Citation

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MLA
De Kimpe, Jurgen, et al. “More than Tenfold Increase of Arsenic in Serum and Packed Cells of Chronic Hemodialysis Patients.” AMERICAN JOURNAL OF NEPHROLOGY, vol. 13, no. 6, 1993, pp. 429–34, doi:10.1159/000168658.
APA
De Kimpe, J., Cornelis, R., Mees, L., Van Lierde, S., & Vanholder, R. (1993). More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients. AMERICAN JOURNAL OF NEPHROLOGY, 13(6), 429–434. https://doi.org/10.1159/000168658
Chicago author-date
De Kimpe, Jurgen, Rita Cornelis, L. Mees, Stijn Van Lierde, and Raymond Vanholder. 1993. “More than Tenfold Increase of Arsenic in Serum and Packed Cells of Chronic Hemodialysis Patients.” AMERICAN JOURNAL OF NEPHROLOGY 13 (6): 429–34. https://doi.org/10.1159/000168658.
Chicago author-date (all authors)
De Kimpe, Jurgen, Rita Cornelis, L. Mees, Stijn Van Lierde, and Raymond Vanholder. 1993. “More than Tenfold Increase of Arsenic in Serum and Packed Cells of Chronic Hemodialysis Patients.” AMERICAN JOURNAL OF NEPHROLOGY 13 (6): 429–434. doi:10.1159/000168658.
Vancouver
1.
De Kimpe J, Cornelis R, Mees L, Van Lierde S, Vanholder R. More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients. AMERICAN JOURNAL OF NEPHROLOGY. 1993;13(6):429–34.
IEEE
[1]
J. De Kimpe, R. Cornelis, L. Mees, S. Van Lierde, and R. Vanholder, “More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients,” AMERICAN JOURNAL OF NEPHROLOGY, vol. 13, no. 6, pp. 429–434, 1993.
@article{196975,
  abstract     = {{Arsenic concentrations were determined in serum and packed cells of 7 chronic hemodialysis patients, in fresh dialysate and in a heparin solution. The analytical technique was radiochemical neutron activation analysis. The accuracy of the method was tested by the analysis of As in certified reference materials. Patients showed elevated serum and packed cell arsenic concentrations compared with controls (serum, range: 2.3-79.8 ng As/ml, median: 11.5 ng As/ml; versus range: 0.132-4.783 ng As/ml, median: 0.38 ng As/ml; packed cells, range: 2.1-68.4 ng As/g, median: 9.5 ng As/g; versus range: 0.51-14.44 ng As/g, median: 3.17 ng As/g). Arsenic concentrations remained unaltered, before versus after a single hemodialysis treatment. The arsenic contents of serum and packed cells were significantly correlated (n = 7, r = 0.96, p < 0.05). No arsenic could be detected in the heparin solution or in the dialysate.}},
  author       = {{De Kimpe, Jurgen and Cornelis, Rita and Mees, L. and Van Lierde, Stijn and Vanholder, Raymond}},
  issn         = {{0250-8095}},
  journal      = {{AMERICAN JOURNAL OF NEPHROLOGY}},
  keywords     = {{ARSENIC,CHRONIC RENAL FAILURE,CHRONIC HEMODIALYSIS,SERUM,PACKED CELLS,RADIOCHEMICAL NEUTRON ACTIVATION ANALYSIS,BIOLOGICAL REFERENCE MATERIAL,TRACE-ELEMENTS}},
  language     = {{eng}},
  number       = {{6}},
  pages        = {{429--434}},
  title        = {{More than tenfold increase of arsenic in serum and packed cells of chronic hemodialysis patients}},
  url          = {{http://doi.org/10.1159/000168658}},
  volume       = {{13}},
  year         = {{1993}},
}
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