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Limitations of quantitative radionuclide bone scanning in the evaluation of total knee replacement

H Verlooy, Jan Victor UGent, L Renson, A vandecruys, P Drent, L Mortelmans and M De Roo (1993) CLINICAL NUCLEAR MEDICINE. 18(8). p.671-674
abstract
To establish the value of quantitative radionuclide bone scanning after total knee replacement, 21 patients were scheduled for examination. Eight patients were scanned more than 1 year after surgery (group 1), and 13 within the first postsurgical year (group 2). Ratios were calculated for three regions of interest. The ratio was defined as the counts per pixel for each region of interest, normalized by dividing them by the counts per pixel of the ipsilateral femoral shaft. There was no significant difference in uptake between control subjects and patients in group 2, indicating that the test was not reliable within this time period. No statistical difference was found between the uptake scores in groups 1 and 2, demonstrating that an uninterpretable period of 1 year is perhaps too short. Using a ratio of more than three, seen more than 1 year after surgery as pathologic, a sensitivity of 100%, a specificity of 33%, and an accuracy of 75% was found. Quantitative bone scanning is a very sensitive test for detecting complications, but it is nonspecific in diagnosing loosening of total knee arthroplasties. The value of quantitative scanning presumably lies in the follow-up of patients as an objective method for the evaluation of sequential scanning. Nevertheless, radionuclide data need to be interpreted in correlation with clinical and radiologic findings.
Please use this url to cite or link to this publication:
author
organization
year
type
journalArticle (original)
publication status
published
subject
journal title
CLINICAL NUCLEAR MEDICINE
Clin. Nucl. Med.
volume
18
issue
8
pages
671 - 674
Web of Science type
Article
ISSN
0363-9762
DOI
10.1097/00003072-199308000-00010
language
English
UGent publication?
no
classification
A1
id
1967920
handle
http://hdl.handle.net/1854/LU-1967920
date created
2011-12-15 12:03:47
date last changed
2016-12-19 15:45:31
@article{1967920,
  abstract     = {To establish the value of quantitative radionuclide bone scanning after total knee replacement, 21 patients were scheduled for examination. Eight patients were scanned more than 1 year after surgery (group 1), and 13 within the first postsurgical year (group 2). Ratios were calculated for three regions of interest. The ratio was defined as the counts per pixel for each region of interest, normalized by dividing them by the counts per pixel of the ipsilateral femoral shaft. There was no significant difference in uptake between control subjects and patients in group 2, indicating that the test was not reliable within this time period. No statistical difference was found between the uptake scores in groups 1 and 2, demonstrating that an uninterpretable period of 1 year is perhaps too short. Using a ratio of more than three, seen more than 1 year after surgery as pathologic, a sensitivity of 100\%, a specificity of 33\%, and an accuracy of 75\% was found. Quantitative bone scanning is a very sensitive test for detecting complications, but it is nonspecific in diagnosing loosening of total knee arthroplasties. The value of quantitative scanning presumably lies in the follow-up of patients as an objective method for the evaluation of sequential scanning. Nevertheless, radionuclide data need to be interpreted in correlation with clinical and radiologic findings.},
  author       = {Verlooy, H and Victor, Jan and Renson, L and vandecruys, A and Drent, P and Mortelmans, L and De Roo, M},
  issn         = {0363-9762},
  journal      = {CLINICAL NUCLEAR MEDICINE},
  language     = {eng},
  number       = {8},
  pages        = {671--674},
  title        = {Limitations of quantitative radionuclide bone scanning in the evaluation of total knee replacement},
  url          = {http://dx.doi.org/10.1097/00003072-199308000-00010},
  volume       = {18},
  year         = {1993},
}

Chicago
Verlooy, H, Jan Victor, L Renson, A vandecruys, P Drent, L Mortelmans, and M De Roo. 1993. “Limitations of Quantitative Radionuclide Bone Scanning in the Evaluation of Total Knee Replacement.” Clinical Nuclear Medicine 18 (8): 671–674.
APA
Verlooy, H., Victor, J., Renson, L., vandecruys, A., Drent, P., Mortelmans, L., & De Roo, M. (1993). Limitations of quantitative radionuclide bone scanning in the evaluation of total knee replacement. CLINICAL NUCLEAR MEDICINE, 18(8), 671–674.
Vancouver
1.
Verlooy H, Victor J, Renson L, vandecruys A, Drent P, Mortelmans L, et al. Limitations of quantitative radionuclide bone scanning in the evaluation of total knee replacement. CLINICAL NUCLEAR MEDICINE. 1993;18(8):671–4.
MLA
Verlooy, H, Jan Victor, L Renson, et al. “Limitations of Quantitative Radionuclide Bone Scanning in the Evaluation of Total Knee Replacement.” CLINICAL NUCLEAR MEDICINE 18.8 (1993): 671–674. Print.